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Background; Salivary gland carcinomas (SGC) cover a heterogeneous group of malignancies with a lack of data of high-level evidence. Methods; Clinical data of 127 patients treated for SGC at a university cancer center between 2002 and 2017 were analyzed retrospectively. The association of clinicopathological characteristics, treatment modalities, adverse events, and outcome was assessed. Results: Patients received surgery (n)=)65), surgery followed by (chemo-)radiotherapy (n)=)56), or primary (chemo-)radiotherapy (n)=)6). Injury to the cranial nerves or their branches was the most frequent surgical complication affecting 40 patients (33.1%). Ten year overall and progression-free survival rates were 73.2% and 65.4%, respectively. Parotid tumor site, advanced tumor, and positive nodal stage remained independent negative prognostic factors for overall survival, loco-regional and distant tumor control in multivariate analysis. Conclusions: Optimizing treatment strategies for SGC, depending on distinct clinicopathological factors, remains challenging due to the low incidence rates of the disease.
West Germany and the Iron Curtain takes a fresh look at the history of the Federal Republic and the German re-unification process from the spatial perspective of the West German borderlands that emerged along the volatile inter-German border after 1945. The book is the first environmental history of the Iron Curtain.
Long trusted as the most comprehensive, up-to-date and user-friendly grammar available, HAMMER'S GERMAN GRAMMAR AND USAGE provides you with a complete guide to German as it is written and spoken today. This new edition includes: -concise descriptions of the main grammatical phenomena of German and their use -examples of grammar taken from contemporary German, helping you to understand the underlying grammatical principles more quickly -invaluable guidance on pronuciation and the German accent -discussion of new words from English roots such as 'zertweeten' ('to tweet'), helping you to communicate in German as used by Germans today -clarification on the spelling reform and current spellings of German, thus increasing your confidence while writing and reading in German. Praised for its clear layout and lucid explanations, this new edition distinguishes the most common forms of usage, both formal and informal, and offers you a combination of reference grammar and manual of current usage that you will find invaluable, whether a student or a teacher, at intermediate or advanced level.
The twentieth century has been scarred by political violence and genocide, reaching its extreme in the Holocaust. Yet, at the same time, the century has been marked by a growing commitment to human rights. This volume highlights the importance of history-
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