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An Introduction to Population Genetics Theory
This text book, originally published in 1970, presents the field of population genetics, starting with elementary concepts and leading the reader well into the field. It is concerned mainly with population genetics in a strict sense and deals primarily with natural populations and less fully with the rather similar problems that arise in breading live stock and cul t i vat ed plans . The emphasis is on the behavior of genes and population attributes under natural selection where the most important measure is Darwinian fitness. This text is intended for graduatestudents and advanced undergraduates in genetics and population biology. This book steers a middle course between completely verbal biological arguments and the rigor of the mathematician. The first two-thirds of the book do not require advanced mathematical background. An ordinary knowledge of calculus will suffice. The latter parts of the book, which deal with population stochastically, use more advanced methods.
Choosing Selection
Describes the hypothesis that Darwin’s “natural selection,” reformulated by R.A. Fisher, J.B.S. Haldane, and S. Wright in the light of Mendelian genetics, is the exclusive mechanism for biological evolution. During the 1930s, alternatives such as Lamarchism, macromutations, and orthogenesis were rejected in favor of natural selection acting on small mutations, but there were disagreements about the role of random genetic drift in evolution. By the 1950s, research by T. Dobzhansky, E.B. Ford, and others persuaded leading evolutionists that natural selection was so powerful that drift was unimportant. This conclusion was accepted by most; however, some biology textbooks and popular articles mentioned drift in the late 1960s.
Evolution
Spanning evolutionary science from its inception to its latest findings, from discoveries and data to philosophy and history, this book is the most complete, authoritative, and inviting one-volume introduction to evolutionary biology available. Clear, informative, and comprehensive in scope, Evolution opens with a series of major essays dealing with the history and philosophy of evolutionary biology, with major empirical and theoretical questions in the science, from speciation to adaptation, from paleontology to evolutionary development (evo devo), and concluding with essays on the social and political significance of evolutionary biology today. A second encyclopedic section travels the spe...
Technical Bulletin
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Philosophy of Biology
Philosophy of Biology is a rapidly expanding field. It is concerned with explanatory concepts in evolution, genetics, and ecology. This collection of 25 essays by leading researchers provides an overview of the state of the field. These essays are wholly new; none of them could have been written even ten years ago. They demonstrate how philosophical analysis has been able to contribute to sometimes contested areas of scientific theory making.-Written by internationally acknowledged leaders in the field- Entries make original contributions as well as summarizing state of the art discoveries in the field- Easy to read and understand
Current Developments in Anthropological Genetics
The papers in this volume were presented as part of the University of Kansas Department of Anthropology Distinguished Lecture Program on Anthro pological Genetics. Consecutively, each contributor spent approximately a week on the campus at Lawrence participating in a seminar. The contributors to this volume were not on campus at one time, but visited us on alternating weeks; hence, a symposium-type interchange was not possible between all participants. However, the students and faculty of Kansas University acted as a sounding board. This volume can be considered a companion and continuation of Methods and Theories of Anthropological Genetics, which was based upon a symposium on the state of the art in 1971. This present volume reflects what we consider to be some of the advances and current developments in anthropological genetics since 1973. Emphasis has shifted, to some degree, away from population struc ture analysis (as depicted in Crawford and Workman) to genetic epidemiology. However, population structure still remains a fertile and ongoing area of research with many theoretical questions still remaining unanswered.
Theoretical Aspects of Population Genetics
To show the importance of stochastic processes in the change of gene frequencies, the authors discuss topics ranging from molecular evolution to two-locus problems in terms of diffusion models. Throughout their discussion, they come to grips with one of the most challenging problems in population genetics--the ways in which genetic variability is maintained in Mendelian populations. R.A. Fisher, J.B.S. Haldane, and Sewall Wright, in pioneering works, confirmed the usefulness of mathematical theory in population genetics. The synthesis their work achieved is recognized today as mathematical genetics, that branch of genetics whose aim is to investigate the laws governing the genetic structure of natural populations and, consequently, to clarify the mechanisms of evolution. For the benefit of population geneticists without advanced mathematical training, Professors Kimura and Ohta use verbal description rather than mathematical symbolism wherever practicable. A mathematical appendix is included.
A Century of Mendelism in Human Genetics
In 1901 William Bateson, Professor of Biology at Cambridge, published a renewed version of a lecture which he had delivered the year before to the Royal Horticultural Society in London (reprinted in the book as an appendix). In this lecture he recognized the importance of the work completed by Gregor Mendel in 1865, and brought it to the notice of
Population Genetics, Molecular Evolution, and the Neutral Theory
One of this century's leading evolutionary biologists, Motoo Kimura revolutionized the field with his random drift theory of molecular evolution—the neutral theory—and his groundbreaking theoretical work in population genetics. This volume collects 57 of Kimura's most important papers and covers forty years of his diverse and original contributions to our understanding of how genetic variation affects evolutionary change. Kimura's neutral theory, first presented in 1968, challenged the notion that natural selection was the sole directive force in evolution. Arguing that mutations and random drift account for variations at the level of DNA and amino acids, Kimura advanced a theory of evol...
