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The DNA, RNA, and Histone Methylomes
This book reviews the chemical, regulatory, and physiological mechanisms of protein arginine and lysine methyltransferases, as well as nucleic acid methylations and methylating enzymes. Protein and nucleic acid methylation play key and diverse roles in cellular signalling and regulating macromolecular cell functions. Protein arginine and lysine methyltransferases are the predominant enzymes that catalyse S-adenosylmethionine (SAM)-dependent methylation of protein substrates. These enzymes catalyse a nucleophilic substitution of a methyl group to an arginine or lysine side chain nitrogen (N) atom. Cells also have additional protein methyltransferases, which target other amino acids in peptidy...
Advancement of GI-Science and Sustainable Agriculture
This book describes the contributing aspects of contemporary developments related to sustainable agricultural resources and assessment of sustainable agriculture in developing nations. The issues like food crisis and declining agro-productivity, post-pandemic food security, zonation and mapping technique viewing food crisis, biotechnology and sustainable agricultural, scaling hunger indices, health hazard and food crisis, changing climate and food availability, consumer load and fertilizer usage, growing demand and increasing usage of harmful chemical in agro-fields are regarded as serious concerns. Thereafter, the scope of sustainable agricultural potentiality (SAP) modeling, amidst the are...
Shields Textbook of Glaucoma
Thoroughly updated, and now in full color, Shields' Textbook of Glaucoma, Sixth Edition is a clinically focused and practical textbook for general ophthalmologists treating patients with glaucoma. This classic text offers a rational approach to the medical and surgical management of glaucoma and presents a total care plan for the patient. This edition has five new or reconfigured chapters—management of the glaucoma patient/approach to the patient; principles of medical therapy; adrenergic agonists and antagonists; cholinergic stimulators and hyperosmotic agents; and neuroprotection and other investigational drugs. The book examines new technologies for intraocular pressure assessment and current diagnostic technologies such as optical coherence tomography, spectral domain optical coherence tomography, Heidelberg retinal tomograph, and GDx. Noted experts detail advances in surgical treatment of glaucoma including new glaucoma implants and angle surgery. Coverage also includes advances in genetics of glaucomatous diseases. A companion website includes the fully searchable text and an image bank.
Climate Change and Crop Production
Trends in population growth suggest that global food production is unlikely to satisfy future demand under predicted climate change scenarios unless rates of crop improvement are accelerated. This book provides an overview of the essential disciplines required for sustainable crop production in unpredictable environments.
Cell Biology and Translational Medicine, Volume 17
Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. This book series 'Cell Biology and Translational Medicine (CBTMED)' as part of Springer Nature’s longstanding and very successful Advances in Experimental Medicine and Biology book series, has the goal to accelerate advances by timely information exchange. Emerging areas of regenerative medicine and translational aspects of stem cells are covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the 17th volume of a continuing series.
16th European Symposium on Computer Aided Process Engineering and 9th International Symposium on Process Systems Engineering
This proceedings book contains the papers presented at the joint conference event of the 9th Symposium on Process Systems Engineering (PSE'2006) and the 16th European Symposium on Computer Aided Process Engineering (ESCAPE-16), held in Garmisch-Partenkirchen, Germany, from July 9 – July 13, 2006. The symposium follows the first joint event PSE'97 / ESCAPE-7 in Trondheim, Norway (1997). The last two venues of the ESCAPE symposia were Barcelona, Spain (2005) and Lisbon, Portugal (2004) and the most recent PSE symposia were held in Kunming, China (2003) and Keystone, Colorado, USA (2000). The purpose of both series is to bring together the international community of researchers engineers who ...
Improving Responses to Immunotherapy in Glioblastoma Multiforme
Glioblastoma multiforme (GBM) is a uniformly fatal primary brain tumour. Whilst many therapeutic interventions have been studied pre-clinically very few new therapies have been approved for the use of GBM therapy. These tumours present a unique challenge due to their location within the brain, making delivery of therapeutic interventions challenging. Active immunotherapy represents an attractive avenue for therapy, with activated immune cells being shown to cross the blood brain barrier and penetrate brain tumours. Despite several advances being made in numerous other cancer types, many immunotherapeutic interventions in GBM have failed to make it past phase 3 clinical trials and as of now (2022) no immunotherapeutic interventions have been approved for the therapy of GBM.
Index Medicus
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Ozone Air Pollution in the Sierra Nevada - Distribution and Effects on Forests
The book contains information on geology, climate and vegetation of the Sierra Nevada with a special emphasis on air pollution effects on the mixed conifer forests. A history of the extent of air pollution effects on mixed conifer forests, especially ponderosa and Jeffrey pines is provided. The physiological basis for ozone-type injury development in ponderosa pine, a discussion of ozone uptake by plants at different levels of biological organization and the effects of air pollution and other stresses on mountain forests are discussed. A considerable portion of the book is dedicated to development of statistical models and maps of ambient ozone distribution in the Sierra Nevada based on the ...
Physics Briefs
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