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Introduction to Psychoneuroimmunology
Health is maintained by the coordinated operation of all the biological systems that make up the individual. The Introduction to Psychoneuroimmunology, Second Edition, presents an overview of what has been discovered by scientists regarding how bodily systems respond to environmental challenges and intercommunicate to sustain health. The book touches on the main findings from the current literature without being overly technical and complex. The result is a comprehensive overview of psychoneuroimmunology, which avoids oversimplification, but does not overwhelm the reader. - Single authored for consistency of breadth and depth, with no redundancy of coverage between chapters - Covers endocrine-immune modulation, neuro-immune modulation, and the enhancing or inhibiting processes of one or more systems on the others - Expanded use of figures, tables, and text boxes
The Handbook of Stress
The Handbook of Stress: Neuropsychological Effects on the Brain is an authoritative guide to the effects of stress on brain health, with a collection of articles that reflect the most recent findings in the field. Presents cutting edge findings on the effects of stress on brain health Examines stress influences on brain plasticity across the lifespan, including links to anxiety, PTSD, and clinical depression Features contributions by internationally recognized experts in the field of brain health Serves as an essential reference guide for scholars and advanced students
Brain, Behavior and Epigenetics
Biomedical research in the first decade of the 21st century has been marked by a rapidly growing interest in epigenetics. The reasons for this are numerous, but primarily it stems from the mounting realization that research programs focused solely on DNA sequence variation, despite their breadth and depth, are unlikely to address all fundamental aspects of human biology. Some questions are evident even to non-biologists. How does a single zygote develop into a complex multicellular organism composed of dozens of different tissues and hundreds of cell types, all genetically identical but performing very different functions? Why do monozygotic twins, despite their stunning external similaritie...
Cytokines, Stress, and Depression
Cytokines had been characterized in the early eighties as communication mole cules between immune cells, and between immunocytes and other peripheral cells, such as fibroblasts and endothelial cells. They play a key role in the regulation of the immune response and the coordination of the host response to infection. Based on these biological properties, nobody would have predicted that one decade later cytokines would burst upon neurosciences and permeate into several avenues of current research. In neurology, the connection between cytokines and inflammation, and the demonstration of a pivotal role of some of these molecules in cell death by apoptosis, prompted the investigation of their in...
Handbook of Microdialysis
Microdialysis is currently one of the most important in vivo sampling methods in physiology and pharmacology. It is used to determine the chemical components of the fluid in the extracellular space of tissues. The technique is now well established in neuroscience research and is used excessively in behavioral neuroscience to determine the concentrations and identities of molecules in brain tissues, and their change due to behavior, hormonal and transmitter changes in the nervous system. The book provides a detailed comprehensive overview of the technology and its applications, including application in pathology, drug development, and the application in the clinic. The authors are all well kn...
Epigenetics of Lifestyle
Recent advances in the fields of genomics and bioinformatics have made it increasingly clear that genetic sequence alone cannot explain how the genome regulates the development and function of complex multicellular organisms both in health and disease. This inference has led to the expansion of epigenetics as a discipline. Epigenetics refers to the way in which the environment in the wide sense participates in the regulation of gene expression. Several studies show that the well-known beneficial role of a healthy lifestyle over a number of pathologies or as a pre-emptive therapy is at least in part exerted through epigenetic mechanisms, thus giving rise to a new paradigm of preventive medici...
A Physiotherapist's Guide to Understanding and Managing ME/CFS
Myalgic encephalomyelitis, also known as Chronic Fatigue Syndrome, is a deeply complex and multi-system condition which has historically suffered from a lack of awareness within physiotherapy education and practice. Similarities in presentation between this condition and Long Covid make this comprehensive and evidence-based guide for physiotherapists even more timely and important. This guide includes an in-depth explanation and history of ME/CFS whilst also describing symptoms, varying degrees of severity, and how to manage ME/CFS in children. It also provides detailed management advice and discussion on how the information can directly inform physiotherapy practice, supplemented with patient case studies.
Immune Modulating Agents
Discussing the systemic immune response in the contexts of health, disease, and therapy, this unique resource-the only broadly based book of its kind available on the subject-offers comprehensive examinations of the pathways and agents that affect the human immune response and provides state-of-the-art presentations on practical methods of immune modulation. Focuses on the immune response and modulation in infectious diseases, such as HIV, hepatitis, and parasitic infections and highlights immune modulating agents in gastrointestinal diseases, sepsis, cancer, and autoimmunity! Written by over 50 international authorities representing distinguished institutions in nine countries, Immune Modul...
Motivation and Cognitive Control
Individuals do not always perform to their full capability on cognitive tasks. When this occurs, the usual explanation is that the individual was not properly motivated. But this begs the important question: How and why does motivation interact with and influence cognitive processing and the control processes that regulate it? What are the underlying mechanisms that govern such interactions? Motivation has been an important component of psychology and neuroscience throughout the history of the field, but has recently been rejuvenated by rapidly accelerating research interest in the nature of motivation-cognition interactions, particularly as they impact control processes and goal-directed be...
How Children Succeed
A foremost "New Yorker" and "New York Times" journalist reverses three decades of thinking about what creates successful children, solving the mysteries of why some succeed and others fail -- and of how to move individual children toward their full potential for success.
