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Recent advances in the fields of genomics and bioinformatics have made it increasingly clear that genetic sequence alone cannot explain how the genome regulates the development and function of complex multicellular organisms both in health and disease. This inference has led to the expansion of epigenetics as a discipline. Epigenetics refers to the way in which the environment in the wide sense participates in the regulation of gene expression. Several studies show that the well-known beneficial role of a healthy lifestyle over a number of pathologies or as a pre-emptive therapy is at least in part exerted through epigenetic mechanisms, thus giving rise to a new paradigm of preventive medici...
This book looks at where stem cell technology is presently and how it is instrumental in advancing the field of disease modeling and cell transplantation. By focusing on major human disorders such as Alzheimer’s disease, cancer, and heart disorders, the book summarizes the major findings in the field of human stem cells and dissect the current limitations on our understanding of stem cells biology. The chapters focus on the genetics, genomics, epigenetics and physiology of stem cells models, together with technological advances on molecular biology such as CRISPR/Cas9 or epigenetic editing, that will be instrumental in the future of human disease modeling and treatment. In base of the limi...
Covering a broad and novel approach on the subject of MODYs, this book looks into the future of molecular genetic and biochemical research in this area. It is recommended reading for basic research scientists in the area of diabetes mellitus, academically oriented endocrinologists and clinical researchers.
Mystery illness can be helped, and this book lays the groundwork for it! Can a water-damaged building ruin your health and cause debilitating exhaustion, chronic pain, insomnia, anxiety, obesity and "brain fog?" Could a flood or wet basement make you sick even if it has long dried out? Building on its predecessor, Nutrition and Integrative Medicine for Clinicians: Volume Two is an essential, peer-reviewed resource for practitioners to help patients with various illnesses found in society, including those contracted from water-damaged structures, that can lay the groundwork for a healthy road to recovery. Written by authors at the forefront of their respective fields, this book presents infor...
This second edition volume expands on the previous edition with updated methodologies and practical tips to overcome obstacles associated with experimentation pertaining to chemistry, biology, physiology, pathology, medical and dental sciences, and pharmacology of CCN proteins. The chapters in this book cover topics such as CCN4 immunofluorescence for tissue microarray; utilizing public molecular biological databases for CCN family research; the effects of CCN4 on pancreatic beta cell proliferation; gene expression analysis of CCNs; novel cell biological assays for measuring bone remodeling activities of CCN proteins; and the function of CCN2 in tubular epithelium cells with a focus on renal...
Passats cent anys del naixement de Joan Llacuna aquest llibre fixa i dóna conèixer per primera vegada la seva obra, completada amb una excel lent biografia de Jaume Farrés Cobeta, que permetrà aprofundir en el coneixement de la vida, el tarannà i la personalitat del poeta.
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