Welcome to our book review site go-pdf.online!
You may have to Search all our reviewed books and magazines, click the sign up button below to create a free account.
Drug Discovery and Evaluation: Methods in Clinical Pharmacology
Drug Discovery and Evaluation has become a more and more difficult, expensive and time-consuming process. The effect of a new compound has to be detected by in vitro and in vivo methods of pharmacology. The activity spectrum and the potency compared to existing drugs have to be determined. As these processes can be divided up stepwise we have designed a book series "Drug Discovery and Evaluation" in the form of a recommendation document. The methods to detect drug targets are described in the first volume of this series "Pharmacological Assays" comprising classical methods as well as new technologies. Before going to man, the most suitable compound has to be selected by pharmacokinetic studi...
Drug Discovery and Evaluation
This book is a landmark in the continuously changing world of drugs. It is essential reading for scientists and managers in the pharmaceutical industry who are involved in drug finding, drug development and decision making in the development process.
Drug Discovery and Evaluation
This reference book contains a comprehensive selection of the most frequently used assays for reliably detecting pharmacological effects of potential drugs, including tests for cardiovascular, analgesic, psychotropic, metabolic, endocrine, respiratory, renal, and immunomodulatory activities. Each of the over 700 assays comprises a detailed protocol with the purpose and rationale of the method, a description of the experimental procedure, a critical assessment of the results and their pharmacological and clinical relevance, and pertinent references. Identification of specific tests is facilitated by the enclosed CD-ROM which allows for a quick and full text research. An appendix with guidelines and legal regulations for animal experiments in various countries will help to plan these experiments properly in accordance with the welfare of laboratory animals.
Simulation, Modeling, and Programming for Autonomous Robots
Why are the many highly capable autonomous robots that have been promised for novel applications driven by society, industry, and research not available - day despite the tremendous progress in robotics science and systems achieved during the last decades? Unfortunately, steady improvements in speci?c robot abilities and robot hardware have not been matched by corresponding robot performance in real world environments. This is mainly due to the lack of - vancements in robot software that master the development of robotic systems of ever increasing complexity. In addition, fundamental open problems are still awaiting sound answers while the development of new robotics applications s- fersfrom...
Road Test
None
Im Kielwasser der Wikinger und Hanseaten
Kapitän Hans-Jürgen Zydek hat so manches erlebt: Im fünften Band seiner Erinnerungen erzählt er von seinem bewegten Leben erst in der Rheinschifffahrt und dann, endlich als Kapitän seines eigenen Schiffes Jirina, auf dem Meer; von den Küsten und Häfen Nordeuropas, von waghalsigen Manövern in Stürmen und Eis, turbulenten Tagen und Nächten - und von Zeiten der Ruhe und des Glücks, die oft mit seiner Familie zu tun haben. "Ebbe und Flut", so sagt er selber, "das waren die Gezeiten meines Lebens." Auf seinen abenteuerlichen Fahrten folgt er nicht nur den Routen der Wikinger und Hanseaten, sondern er begibt sich auch auf die Spuren seines eigenen Vaters, als er, inzwischen Rentner, zusammen mit seinem Bruder auf dem norwegischen Olavsweg nach Trondheim pilgert. Eine Seefahrt ist nicht immer lustig - aber ziemlich oft. Im Kilewasser der Wikinger und Hanseaten ist ein Buch voller Abenteuer und unvergesslicher Geschichten, in denen man hautnah mitbekommt, wie das Leben in der See- und Binnenschifffahrt so spielt. Wieder ein echter Zydek.
Basic Course in Race Car Technology
The focus of the book is on the driving dynamics of racing vehicles. The interaction of the tyre, the aerodynamics, of the chassis and the limited slip differential specific to racing vehicles is dealt with. A chapter on the basics of vehicle dynamics makes it possible to get started with this topic even without prior automotive engineering training. A historical review and a consideration of the essential safety aspects create an understanding of higher-level requirements, which are specified, for example, by the technical regulations.
Synthesis and Applications of Isotopically Labelled Compounds
This volume provides an authoritative and comprehensive coverage of the most recent advances in the production, synthesis, analysis and applications of isotopically labelled compounds. It focuses especially on areas of significant growth since the immediately preceding Seventh International Isotope Society Meeting held in Dresden, Germany in June 2000. Contributions are drawn from major research groups around the world, providing valuable information to research community with interests in the following areas: New methodologies in the production of isotopes Novel synthetic and biosynthetic approaches to isotopically labelled compounds Analysis of isotopically labeled compounds Application of isotopically labelled compounds in medical, agricultural, nutritional and environmental research and development Investigation and elucidation or organic and bioorganic mechanisms and pathways Regulatory and safety perspectives The next Symposium in this series will be held at Edinburgh, Scotland in the summer of 2006.
