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Sustainable Waste Management
This volume presents part of the proceedings of two symposia held under the umbrella of Advances in Waste Management, an international meeting organised by the University of Dundees Concrete Technology Unit.
Drug Discovery and Evaluation: Pharmacological Assays
The new edition of this successful reference offers both cutting-edge and classic pharmacological methods. Thoroughly revised and expanded to two volumes, it offers an updated selection of the most frequently used assays for reliably detecting the pharmacological effects of potential drugs. Every chapter has been updated, and numerous assays have been added. Each of the more than 1,000 assays comprises a detailed protocol outlining purpose and rationale, and a critical assessment of the results and their pharmacological and clinical relevance.
Drug Discovery and Evaluation
This book is a landmark in the continuously changing world of drugs. It is essential reading for scientists and managers in the pharmaceutical industry who are involved in drug finding, drug development and decision making in the development process.
Drug Discovery and Evaluation: Methods in Clinical Pharmacology
Drug Discovery and Evaluation has become a more and more difficult, expensive and time-consuming process. The effect of a new compound has to be detected by in vitro and in vivo methods of pharmacology. The activity spectrum and the potency compared to existing drugs have to be determined. As these processes can be divided up stepwise we have designed a book series "Drug Discovery and Evaluation" in the form of a recommendation document. The methods to detect drug targets are described in the first volume of this series "Pharmacological Assays" comprising classical methods as well as new technologies. Before going to man, the most suitable compound has to be selected by pharmacokinetic studi...
Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays
Many aspects of drug safety have become an outstanding and even persistent issue and may occur during the process of both drug discovery and development. Until 15 years ago, drug discovery and evaluation was primarily a sequential process starting with the selection of the most pharmacologically active compound from a series of newly synthesized small molecule chemical series by means of distinctive pharmacological assays. Safety aspects were addressed by evaluation of the selected compound at high doses in a series of specific studies directed at indications other than the intended indication of the new compound. These tests are then followed by pharmacokinetic studies, which are primarily ...
Professional Paper
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GeNeDis 2016
The 2nd World Congress on Geriatrics and Neurodegenerative Disease Research (GeNeDis 2016), focuses on recent advances in geriatrics and neurodegeneration, ranging from basic science to clinical and pharmaceutical developments and provides an international forum for the latest scientific discoveries, medical practices and care initiatives. Advanced information technologies are discussed concerning the various research, implementation and policy, as well as European and global issues in the funding of long-term care and medico-social policies regarding elderly people. This volume focuses on the sessions from the conference on computational biology and bioinformatics.
