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Short-Term Bioassays in the Analysis of Complex Environmental Mixtures III
In the four years since the 1978 Symposium on the Application of Short-Term Bioassays in the Fractionation and Analysis of Complex Environmental Mixtures the use of short-term bioassays to evaluate potential health hazards of complex environmental mixtures has substantially increased. Increased research activity has been particularly noticeable in mobile source emissions, where initial observations on the mutagenic activity of diesel particulate extracts reported at the 1978 symposium stimulated the development of major research programs in government and industry. In the absence of appropriate reference materials, the U.S. Environmental Protection Agency initiated comparative genotoxicity s...
Short-Term Bioassays in the Analysis of Complex Environmental Mixtures IV
With this proceedings of the fourth symposium on complex mixtures, we continue to revise and extend our knowledge of genetic methods for the evaluation of chemical mixtures in the environment. The early chapters of this volume are devoted to new bioassay techniques that are directly applicable to the monitoring of environments contaminated with genotoxic chemicals. Microbiological methods have been further refined to meet the special needs of atmospheric monitoring so that very small samples may now be efficiently tested. New in situ methods utilizing green plants actually avoid many of the usual difficulties of sample collection and preparation and offer special advantages in monitoring was...
Short-Term Bioassays in the Analysis of Complex Environmental Mixtures II
More than one hundred short-term bioassays are now available for detecting the toxicity, mutagenicity, and potential carcinogenicity of chemicals. These bioassays were developed and validated with individual compounds, and their principal application was perceived to be in evaluating the health hazard of such materials. However, man is rarely exposed to single chemicals; his exposure to hazardous chemicals is more commonly a multifactorial phenomenon. Although chemical analysis can be used to detect known hazardous compounds, it would be a staggering and expensive task to analyze large numbers of samples for all known or suspected hazardous constituents. Furthermore, the biological activity ...
Risk Analysis
This volume of the series Advances in Risk Analysis consists of papers presented at the 1988 Annual Meeting of the Society for Risk Analysis, which was held October 30 through November 2 at the Mayflower Hotel in Washington, DC. The papers span the gamut of the increasing number of risk assessment topics addressed by the Society since it held its fIrst annual meeting in June 1981, also in Washington DC. Organized to promote interdisciplinary analyses, the Society approaches risks from three broad perspectives: (1) the impact of various risks on the health of the world's populations and on the environment; (2) the social and political implications of specifIc risks, and (3) the management and...
Effective and Safe Waste Management
Effective and safe waste management is dependent on the collaborative interaction of engineers, computer modeling specialists, toxicologists, risk assessment experts, soil scientists, biologists, geologists, chemists and professionals in many other disciplines. To meet the needs of this diverse group, this book covers effective and safe waste management topics in a holistic sense, including air monitoring as well as soil and water monitoring, site-specific evaluation and monitoring as well as generic management, and scientific and regulatory compliance issues as well as public interactions. It is an essential reference for all professionals involved in waste management, monitoring, and risk analysis.
Biodegradation of Nitroaromatic Compounds
During the past five years increased awareness of environmental contamination by nitroaromatic compounds has led to a dramatic increase in research on their biodegradation. The resulting discoveries have markedly extended our understanding of degradation mecha nisms and pathways in bacteria and fungi. Futhermore, this new basic knowledge promises the development of field applications of biodegradation systems for nitroaromatic com pounds. In May of 1994, an International Symposium on the Biodegradation of Nitro aromatic Compounds was held in Las Vegas, Nevada. This symposium brought together the scientists at the frontiers of research into the biodegradation of nitro aromatic compounds. The ...
In Situ Evaluation of Biological Hazards of Environmental Pollutants
The study of the relationship between environmental pollution and human health is in its infancy. The number of substances and mixtures that have been identified in uncontrolled hazardous waste sites or that have been in advertently released into the environment is large and data on how thes~ substances are modified as they interact with one another as they migrate through soil, air, and water are limited. There are also limits on our un derstanding of how these substances may be ingested, inhaled, or absorbed by people. The complexity of possible interactions between biological, chemical, and physical components in a given environment makes it virtually impossible to evaluate the potential ...
EPA Journal
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Research Priorities for Airborne Particulate Matter
In 1997, the U.S. Environmental Protection Agency (EPA) established regulatory standards to address health risks posed by inhaling tiny particles from smoke, vehicle exhaust, and other sources. At the same time, Congress and the EPA began a multimillion dollar research effort to better understand the sources of these airborne particles, the levels of exposure to people, and the ways that these particles cause disease. To provide independent guidance to the EPA, Congress asked the National Research Council to study the relevant issues. The result was a series of four reports on the particulate-matter research program. The first two books offered a conceptual framework for a national research ...
