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Computational Systems Biology of Pathogen-Host Interactions
A thorough understanding of pathogenic microorganisms and their interactions with host organisms is crucial to prevent infectious threats due to the fact that Pathogen-Host Interactions (PHIs) have critical roles in initiating and sustaining infections. Therefore, the analysis of infection mechanisms through PHIs is indispensable to identify diagnostic biomarkers and next-generation drug targets and then to develop strategic novel solutions against drug-resistance and for personalized therapy. Traditional approaches are limited in capturing mechanisms of infection since they investigate hosts or pathogens individually. On the other hand, the systems biology approach focuses on the whole PHI ...
Systems Biology of Transcription Regulation
Transcription regulation is a complex process that can be considered and investigated from different perspectives. Traditionally and due to technical reasons (including the evolution of our understanding of the underlying processes) the main focus of the research was made on the regulation of expression through transcription factors (TFs), the proteins directly binding to DNA. On the other hand, intensive research is going on in the field of chromatin structure, remodeling and its involvement in the regulation. Whatever direction we select, we can speak about several levels of regulation. For instance, concentrating on TFs, we should consider multiple regulatory layers, starting with signali...
Advances in Intelligent Data Analysis X
This book constitutes the refereed proceedings of the 10th International Conference on Intelligent Data Analysis, IDA 2011, held in Porto, Portugal, in October 2011. The 19 revised full papers and 16 revised poster papers resented together with 3 invited papers were carefully reviewed and selected from 73 submissions. All current aspects of intelligent data analysis are addressed, particularly intelligent support for modeling and analyzing complex, dynamical systems. The papers offer intelligent support for understanding evolving scientific and social systems including data collection and acquisition, such as crowd sourcing; data cleaning, semantics and markup; searching for data and assembling datasets from multiple sources; data processing, including workflows, mixed-initiative data analysis, and planning; data and information fusion; incremental, mixed-initiative model development, testing and revision; and visualization and dissemination of results; etc.
Interventional Ultrasound
The first comprehensive, multi-specialty text on ultrasound guidance in interventional procedures, this book uses the authors' extensive clinical experience to provide a full overview of modern interventional ultrasound. For all practitioners, whether new to the procedures or already using them, Interventional Ultrasound offers expert advice and solutions to commonly encountered questions and problems. Special Features: Provides a complete approach to interventional ultrasound, beginning with essential basics on materials, equipment, setup requirements, informed consent issues, microbiologic aspects, and hygiene Covers specific, ultrasound-guided diagnostic and therapeutic interventions in t...
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Roman Ondák
Roman Ondák represents the Slovak Republic at the 2009 Venice Biennale. In this volume the Slovak artist Roman Ondák has brought together some of his works that deal with time, measurement, and surveying along with those that make visible what evades the visual, namely boundaries and experience. Alongside a complete documentation of the exhibition Measuring the Universe, where the museum attendants checked the body size of the visitors throughout its duration, one also finds Failed Fall (2008), a greenhouse's floor filled with dried autumn leaves, and Across that Place (2008), the story of the no longer existing Canal Zone by the Panama Canal. Whether working with installation, photography...
