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The Common Thread
John Sulston was director of the Sanger Centre in Cambridge from 1993 to 2000. There he led the British arm of the international team selected to map the entire human DNA sequence, a feat that was pulled off in record time by an extraordinary collaboration of scientists. Despite innumerable setbacks and challenges from outside competitors the ultimate success of the project can be attributed in large part to John Sulston's own determination, passion and scientific excellence. In this personal account he takes us behind the scenes of one of the largest international scientific operations ever undertaken. He is frank about the competition with Craig Venter and Celera Genomics, which threatened...
Curiosity Guides: The Human Genome
The DNA sequence that comprises the human genome--the genetic blueprint found in each of our cells--is undoubtedly the greatest code ever to be broken. Completed at the dawn of a new millennium, the feat electrified both the scientific community and the general public with its tantalizing promise of new and better treatments for countless diseases, including Alzheimer's, cancer, diabetes, and Parkinson's. Yet what is arguably the most important discovery of our time has also opened a Pandora's box of questions about who we are as humans and how the unique information stored in our genomes can and might be used, making it all the more important for everyone to understand the new science of ge...
Won for All
This is the story of the sequencing of the fly genome as told by one of the participants, Michael Ashburner. Written in a diary-like form, half the story is told in numerous footnotes. Ashburner has written a delightful, candid, irreverent, on-the-scene tale filled with eccentric personalities all focused on a single goal. The book also contains an Epilogue that puts Drosophilaas a model system in historical context, and an Afterword that discusses the impact the genome sequence has had on the study of Drosophila.Also included are portraits by Lewis Miller of some of the principal characters. About the author:Michael Ashburner is Professor of Biology in the Department of Genetics at the University of Cambridge. By training and inclination, he is a Drosophilageneticist, although for more than a decade, he has not been where he belongs – the lab bench – but in front of computer screens. He spent six years at the European Bioinformatics Institute, first as the Institute's Research Programme Coordinator, and then as its Joint-Head. He is a Fellow of the Royal Society and an Honorary Foreign Member of the American Academy of Arts and Sciences.
Reinventing Discovery
"Reinventing Discovery argues that we are in the early days of the most dramatic change in how science is done in more than 300 years. This change is being driven by new online tools, which are transforming and radically accelerating scientific discovery"--
Sydney Brenner's 10-on-10: The Chronicles Of Evolution
Humans now wield a greater influence on the planet than any other species in history, and human-developed technologies like genetic engineering and artificial intelligence stand poised to overtake biological evolution. Just how did we arrive at this unique moment in human history, 14 billion years after the birth of the universe Sydney Brenner's 10-on-10: The Chronicles of Evolution brings together 24 prominent scientists and thinkers to trace the story of evolution through ten logarithmic scales of time. Through expert insights, this unique volume considers how humans found our place in the cosmos, and imagines what lies ahead.Published by Wildtype Books and distributed by World Scientific Publishing Co.
The Life Scientific: Explorers
Inspiring life stories from BBC Radio 4's hit series The Life Scientific 'In showing non-scientists why science offers so many paths to discovery it has no equal' Gillian Reynolds, Telegraph Based on Jim Al-Khalili's ground-breaking interviews, The Life Scientific: Explorers takes science out of its box and introduces us to the men and women who make it happen. The explorers featured in this volume include: Michele Dougherty, the mathematician who persuaded the Cassini mission to Saturn to make a diversion; Richard Fortey on his love of trilobites; Monica Grady, Meteorite Lady; neurosurgeon Henry Marsh on slicing through our thoughts; the Director of the British Antarctic Survey, Jane Francis; Jocelyn Bell Burnell describing how she missed out on a Nobel Prize; Brian Cox on quantum mechanics; and Nobel Prize winner John Sulston on why he thought it would be a good idea to sequence the human genome.
Bird Migration across the Himalayas
The first reference to demonstrate how birds survive the high-altitude Central Asian Flyway and the threats to this unique migration.
C. Elegans II
Defines the current status of research in the genetics, anatomy, and development of the nematode C. elegans, providing a detailed molecular explanation of how development is regulated and how the nervous system specifies varied aspects of behavior. Contains sections on the genome, development, neural networks and behavior, and life history and evolution. Appendices offer genetic nomenclature, a list of laboratory strain and allele designations, skeleton genetic maps, a list of characterized genes, a table of neurotransmitter assignments for specific neurons, and information on codon usage. Includes bandw photos. For researchers in worm studies, as well as the wider community of researchers in cell and molecular biology. Annotation copyrighted by Book News, Inc., Portland, OR
Big Questions in Science
What is life about? How are men and women different? How did the universe begin? We all ponder these questions from time to time but some scientists spend their lives investigating them. Are they anywhere near finding answers? In this exciting new book, leading scientific thinkers address twenty of the really big questions that people have been asking for hundreds of years. The contributors include: John Sulston, who led the British side of the Human Genome Project and who offers his views on whether we can ever end disease; Susan Greenfield, Oxford University professor of pharmacology, who describes what she thinks is a thought; John Barrow, Cambridge professor of mathematical sciences, who...
A Guide to Contemporary Portraits
This is an introductory guide to contemporary portraiture through the prism of the National Portrait Gallery, London. The gallery's director and contemporary curator discuss key works from the collection and invite readers to consider recent developments in portraiture.
