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Research centering on blood flow in the heart continues to hold an important position, especially since a better understanding of the subject may help reduce the incidence of coronary arterial disease and heart attacks. This book summarizes recent advances in the field; it is the product of fruitful cooperation among international scientists who met in Japan in May, 1990 to discuss the regulation of coronary blood flow.
For two decades, Swine in the Laboratory: Surgery, Anesthesia, and Experimental Techniques has been the most respected practical technical guide for medical and veterinary researchers using swine as experimental animals. Extensively updated and expanded since the publication of the second edition in 2007 and now sponsored by the American College of Laboratory Animal Medicine (ACLAM), it continues to be the most authoritative source of scientific and technical information on the use of domestic and miniature swine in research. Additions to the Third Edition Include: New chapters on toxicology, transgenics, cancer models, and necropsy techniques An overview of porcine models that were not incl...
The coronary circulation is unique in that it is responsible for maintaining adequate oxygen and substrate delivery to the organ that generates the pressure needed to drive blood throughout the entire circulatory system. In the simplest terms, coronary blood flow is directly proportional to the arterial pressure gradient across the coronary vasculature and inversely proportional to coronary vascular resistance. However, myocardial perfusion is collectively regulated by a complex variety of mechanisms which include: (1) extravascular compressive forces; (2) diastolic time fraction; (3) coronary perfusion pressure; (4) myocardial metabolism (local metabolic factors); (5) endothelial-derived su...
Just one of a series of volumes on differing aspects of hypoxia, this authoritative text focuses on cutting-edge research at the interface of hypoxia and biomedicine. Hypoxia – or lack of oxygen – is a constant threat to the human body and its vital organs, one that can take its toll in a number of situations. There are many situations in which the threat is heightened in health and disease, but mechanisms have evolved to lessen its detrimental effects. The International Hypoxia Symposia was founded to enable scientists, clinicians, physiologists, immunologists, mountaineers and other interested individuals to share their experiences of the situations associated with the lack of oxygen and the adaptations that allow us to survive.
Flipped learning—in which students view recorded lectures outside of the classroom and then utilize class time to develop a broad range of knowledge and skills—is a relatively new phenomenon. This timely volume examines and organizes the emerging research on flipped learning in higher education. It identifies the types of courses, material, and learning objectives that are most effectively flipped, with specialized advice for faculty in STEM fields, the social sciences, and humanities. The book also provides evidence-based guidance on how to create and disseminate engaging recorded lectures; develop and implement in-class exercises and projects that help students meet learning objectives; orient students to the flipped classroom; and assess the effectiveness of flipped learning.
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This book offers a multifaceted approach to education in the 21st century. It focuses not only on the problems schools have to face nowadays, but also on the numerous challenges that emerge and can be used as opportunities for reflection and renewal in education. The aim of the book is to holistically approach educational reality as shaped by the latest social, political and economic developments. The ultimate goal is not limited to a description of the current situation. Given its range and topicality, this book expands the discussion and examines the role of education in modern society, highlights the challenges and prospects for the schools of the future, enriches the relevant research, provides documented data for action planning in terms of educational policies, and presents examples of good educational practices which will be useful to teachers and everyone who works in education.