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Parkinsonism and the Environment
“The book is comprised of individual reviews with the common goal of providing up-to-date state of the knowledge information on the role the environment plays in the pathogenesis of parkinsonism. The reviews focus on recent advances in the quest of deciphering the molecular and cellular mechanisms of parkinsonian dysfunction, highlight specific emerging dopaminergic toxicants and an alternative experimental model to study the link between environmental exposures and parkinsonism, and provide an update from epidemiological and experimental points of view related to the pesticide exposures and parkinsonism/Parkinson’s Disease association. Foremost experts in their respective fields are the senior authors on each chapter and the book fills a critical void that now exists as a book of similar nature has not been published in the last 15 years. Researchers and clinicians with an interest in Parkinson's Disease and related disorders, as well as toxicologists, graduate students, and the general public who are interested in the contribution of environmental factors to neurological dysfunction are among the readership for this book.”
Oxidative Stress and Redox Signalling in Parkinson’s Disease
Parkinson's Disease is the second most common neurodegenerative disorder affecting millions of people worldwide. In order to find neuroprotective strategies, a clear understanding of the mechanisms involved in the dopaminergic death of cells that progresses the disease is needed. Oxidative stress can be defined as an imbalance between the production of reactive species and the ability to detoxify them and their intermediates or by-products. Oxidative damage to lipids, proteins, and DNA has been detected in autopsies from individuals with Parkinson’s Disease and so links can be made between oxidative stress and Parkinson’s Disease pathogenesis. This book provides a thorough review of the ...
Enzymology and Molecular Biology of Carbonyl Metabolism 13
The continuation of an annual series, Enzymology and Molecular Biology of Carbonyl Metabolism is the largest collection of articles on the three major gene families. The scope of the chapters, contributed by leading international scientists, is wide and covers gene regulation to enzyme mechanisms and protein structure. This is the only publication dealing in such depth with just three gene families. It is an important reference for researchers in toxicology and molecular biology.
Directory of Graduate Research
Faculties, publications and doctoral theses in departments or divisions of chemistry, chemical engineering, biochemistry and pharmaceutical and/or medicinal chemistry at universities in the United States and Canada.
Working in the Context of Austerity
Austerity was presented as the antidote to sluggish economies, but it has had far-reaching effects on jobs and employment conditions. With an international team of editors and authors from Europe, North America and Australia, this illuminating collection goes beyond a sole focus on public sector work and uniquely covers the impact of austerity on work across the private, public and voluntary spheres. Drawing on a range of perspectives, the book engages with the major debates surrounding austerity and neoliberalism, providing grounded analysis of the everyday experience of work and employment.
British Politics
The nature of politics in Britain is being questioned as never before, with Brexit throwing both party and national politics into turmoil. Here, Tony Wright provides the essential context for current debates about the state of British politics, identifying key characteristics of its history and ideas which influence the current political landscape.
Encyclopedia of Chromatography
Thoroughly revised and expanded, this third edition offers illustrative tables and figures to clarify technical points in the articles and provides a valuable, reader-friendly reference for all those who employ chromatographic methods for analysis of complex mixtures of substances. An authoritative source of information, this introductory guide to specific chromatographic techniques and theory discusses the relevant science and technology, offering key references for analyzing specific chemicals and applications in industry and focusing on emerging technologies and uses.
Systems Biology
Systems biology utilises new computational tools to analyse biological processes on an extraordinary scale. We can now study complex biological phenomena within their natural contexts, applying a holistic, systems-based approach. This book explores what this interdisciplinary field is about, and how it will affect our understanding of life.
