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Genome Data Analysis
This textbook describes recent advances in genomics and bioinformatics and provides numerous examples of genome data analysis that illustrate its relevance to real world problems and will improve the reader’s bioinformatics skills. Basic data preprocessing with normalization and filtering, primary pattern analysis, and machine learning algorithms using R and Python are demonstrated for gene-expression microarrays, genotyping microarrays, next-generation sequencing data, epigenomic data, and biological network and semantic analyses. In addition, detailed attention is devoted to integrative genomic data analysis, including multivariate data projection, gene-metabolic pathway mapping, automat...
Fuzzy Systems and Knowledge Discovery
This book constitutes the refereed proceedings of the Third International Conference on Fuzzy Systems and Knowledge Discovery, FSKD 2006, held in federation with the Second International Conference on Natural Computation ICNC 2006. The book presents 115 revised full papers and 50 revised short papers. Coverage includes neural computation, quantum computation, evolutionary computation, DNA computation, fuzzy computation, granular computation, artificial life, innovative applications to knowledge discovery, finance, operations research, and more.
Case Reports in General Cardiovascular Medicine: 2022
This Research Topic aims to collect all the Case Reports submitted to the General Cardiovascular Medicine section. All the Case Reports submitted to this collection will be personally assessed by the Specialty Chief Editor before the beginning of the peer-review process. Please make sure your article adheres to the following guidelines before submitting it. Case Reports highlight unique cases of patients that present with an unexpected diagnosis, treatment outcome, or clinical course. Only Case Reports that are original and significantly advance the field will be considered: 1) RARE case with TYPICAL features 2) FREQUENT case with ATYPICAL features 3) Cases with a convincing response to new treatments, i.e. single case of off-label use
Advances in Natural Computation
This is volume II of the proceedings of the Second International Conference on Natural Computation, ICNC 2006. After a demanding review process 168 carefully revised full papers and 86 revised short papers were selected from 1915 submissions for presentation in two volumes. The 124 papers in the second volume are organized in topical sections on additional topics in natural computation, natural computation techniques applications, hardware, and cross-disciplinary topics.
Medical Biostatistics for Complex Diseases
A collection of highly valuable statistical and computational approaches designed for developing powerful methods to analyze large-scale high-throughput data derived from studies of complex diseases. Such diseases include cancer and cardiovascular disease, and constitute the major health challenges in industrialized countries. They are characterized by the systems properties of gene networks and their interrelations, instead of individual genes, whose malfunctioning manifests in pathological phenotypes, thus making the analysis of the resulting large data sets particularly challenging. This is why novel approaches are needed to tackle this problem efficiently on a systems level. Written by computational biologists and biostatisticians, this book is an invaluable resource for a large number of researchers working on basic but also applied aspects of biomedical data analysis emphasizing the pathway level.
