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Vitiligo
Since the first edition of this book was published, new knowledge has been gained on Vitiligo. This widely revised and updated second edition, written by worldwide experts in the field, fully reflects this progress. The apparently, simple and poorly symptomatic presentation of the disease has been a strong disadvantage to its study, as compared to other common chronic skin disorders such as psoriasis and atopic dermatitis. A good skin-based angle of attack is also lacking because generalized Vitiligo is clearly epitomizing the view of skin diseases as simple targets of a systemic unknown dysregulation (diathesis). This view has mostly restricted Vitiligo to the manifestation of an auto-immun...
Adverse Cutaneous Drug Eruptions
An indispensable tool for understanding, diagnosing and managing this common clinical problem The skin is one of the most frequently involved organs in adverse drug reactions. Occurring with an incidence of 1-5% for certain types of drugs, cutaneous drug eruptions are mostly benign in nature, and comprise the maculopapular type of eruption and urticaria. However, about one third of them require hospital treatment, leading to a considerable burden for the health care system. In this book, a selected group of experts provide an up-to-date, condensed and clinically relevant overview of the field of cutaneous drug eruptions, ranging from epidemiology and genetic predisposition to available therapeutic measures, including rapid drug desensitization. Reflecting the great progress made in recent years in this field, this publication will be a useful tool for a better understanding, diagnosis and management of cutaneous drug eruptions, not only for general physicians, dermatologists and clinical allergologists, but also for nurses and scientists.
Dermatology - E-Book
**Selected for Doody's Core Titles® 2024 in Dermatology**For dermatology residents and trainees, as well as those in clinical practice, Dermatology is the leading reference for understanding, diagnosing, and treating the full spectrum of skin disease—and is the key resource that residents rely on throughout their training and certification. Widely recognized for its easy-in, easy-out approach, this revised 5th Edition turns complex information into user-friendly visual content through the use of clear, templated chapters, digestible artwork, and easy-to-follow algorithms and tables. This two-volume masterwork provides complete, authoritative coverage of basic science, clinical practice of...
Drug Eruptions
Cutaneous adverse drug reactions are common and range from the benign to those which are life-threatening. The clinical presentation of these dermatoses is varied and many may mimic common skin conditions. Consequently, diagnosis in drug-induced skin disease is challenging and the treatment considerations are complex. This book aims to bridge the divide between dermatology and allergy by providing a comprehensive review on the pathomechanisms and clinical features of cutaneous adverse drug reactions. Broken up into three distinct sections: General Considerations, Reaction Patterns, and Special Drug Categories, these chapters cover the common and rare adverse skin reactions and provide information on recent advances - particularly immunopathology and pharmacogenetics - as well as highlighting new adverse drug signals and novel therapies. Drug Eruptions is a must-have resource for dermatologists, allergists, internal physicians and general practitioners.
Impact of the Innate and Adaptive Immune System in Driving Type 1 Inflammatory Skin Disease
Inflammatory skin diseases are frequent in number and often lead to a decreased quality of life in the affected patients. These diseases result from a complex interplay between the innate and adaptive immune systems. Type 1 inflammation is an immune response driven primarily by Th1 cells, which secrete pro-inflammatory cytokines, notably Interferon-gamma. The initiation of Type 1 inflammation is typically triggered by the recognition of antigens associated with intracellular pathogens. Dendritic cells present these antigens to naive T-cells, leading to the differentiation of predominantly Th1 cells, which in turn activate other immune cells, including macrophages and cytotoxic T-cells. In chronic inflammation, the infiltration of T cells drives the perpetuating cycle of inflammation at the epidermal barrier. Th1-induced inflammation can synergize with recruitment and heightened activity of other T cell subsets such as Th17 cells. Typical type 1 inflammatory skin diseases include psoriasis, lichen planus, acne, hidradenitis suppurativa, pityriasis rubra pilaris, adverse cutaneous drug eruptions, and autoimmune disorders such as vitiligo and lupus erythematodes.
Vitiligo, An Issue of Dermatologic Clinics
This issue of Dermatologic Clinics, guest edited by John E. Harris, MD, PhD, is devoted to Vitiligo. Articles in this timely issue include: History of Vitiligo Management; Quality of Life/Burden of Disease; Comorbidities/Systemic Effects; Skin Cancer Risk (NMSC/Melanoma); Presentations, Signs of Activity, Differential Diagnosis; Segmental Vitiligo; Chemical-Induced Vitiligo; Medical Therapy and Maintenance of Vitiligo; Phototherapy and Combination Therapies for Vitiligo; Surgical Therapy; Depigmentation Therapy; Special Considerations in Children with Vitiligo; Role of Diet and Supplements in Vitiligo Management; Genetics; Pathogenesis and Emerging Treatments; and Repigmentation/Melanocyte Regeneration in Vitiligo.
Skin Tissue Models
Skin Tissue Models provides a translational link for biomedical researchers on the interdisciplinary approaches to skin regeneration. As the skin is the largest organ in the body, engineered substitutes have critical medical application to patients with disease and injury – from burn wounds and surgical scars, to vitiligo, psoriasis and even plastic surgery. This volume offers readers preliminary description of the normal structure and function of mammalian skin, exposure to clinical problems and disease, coverage of potential therapeutic molecules and testing, skin substitutes, models as study platforms of skin biology and emerging technologies. The editors have created a table of content...
Harper's Textbook of Pediatric Dermatology
A consummate classic with a fresh approach to pediatric dermatology Children ́s skin is different. Maturation affects the epidermal barrier, the cutaneous microbiome, adnexal structures, vasculature, and transcutaneous absorption of drugs. The immature skin is more susceptible to pathogens and environmental disruption. Many genetic disorders are either present at birth or manifest early in childhood. Skin diseases thus present differently in children than in adults. Pediatric dermatology has seen significant advances over the last decade, particularly in the field of molecular genetics research, which has furthered our understanding of the pathogenesis of many skin diseases and the developm...
Revue de Gascogne; Bulletin de la Société historique de Gascogne
Réimpression inchangée de l'édition originale de 1898. La maison d'édition Anatiposi publie des livres historiques en réimpression. En raison de leur âge, ces livres peuvent présenter des pages manquantes ou une qualité moindre. Notre objectif est de préserver ces livres et de les rendre accessibles au public afin qu'ils ne se perdent pas.
