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Rheumatic Diseases
A wide-ranging account of the immunological mechanisms that underlie many rheumatic diseases, such as rheumatoid arthritis, ankylosing spondylitis and SLE, and the development of effective and rational new therapies.
The Alcohol Hangover
The seeds and fruits (or their parts) of Iberoamerican crops have high nutritional and functional properties which could be utilized in a wide range of foods. The crops included in this book are amaranth (Amaranthus spp.), quinoa (Chenopodium quinoa), kañiwa (Chenopodium pallidicaule), chia (Salvia hispanica L.), Andean maize (Zea mays L.), moringa (Moringa oleifera), yvapuru (Plinia peruviana), kurugua (Sicana odorifera), sacha inchi (Plukenetia huayllabambana), camu camu (Myrciaria dubia), mango (Mangifera indica), tarwi (Lupinus mutabilis), peanut (Arachis hypogaea L.) and taro (Colocasia esculenta), all of them still underutilized. Their cultivation is low; nevertheless, in recent years...
Biologic and Gene Therapy of Autoimmune Disease
The clinical management of autoimmune diseases has proven to be extremely difficult. Current therapies focus on trying to alleviate symptoms, but fail to correct the fundamental immune defects that lead to pathology. To achieve this goal, it is necessary to understand much of the biology of antigen presentation, lymphocyte activation and the effects of cytokines. The articles in this book provide an up-to-date review of current innovative therapies using both biologic and gene therapy for the treatment of selected autoimmune diseases. Therapeutical approaches discussed include oral tolerance, the use of anti-CD4 monoclonal antibodies, IL-10 and anti-TNFa antibodies, DNA vaccination, and gene therapy applied to organ-specific autoimmune disease. Although some of these techniques are still in their infancy, their potential efficacy has been demonstrated in several animal models of autoimmune disease, holding great promise for the future development of treatments. Written by recognized experts in the field, the chapters in this book illustrate the concept of technology transfer from bench to bedside and provide a valuable update for clinicians and scientists in clinical immunology.
The Family and the Nation
Until recently, migration policies primarily targeted labour migrants and asylum seekers. Family migration was taken for granted. But now, many nations are restricting family migration, particularly from poorer countries. The Netherlands have even gone so far as to require family migrants to pass an integration test before being allowed to enter the country. How can this shift in policies be explained? Does it, as some suggest, indicate a new trend towards racist exclusion? This book places family migration policies in the broader perspective of changing family norms. In doing so, it shows the added value of studying immigration law not as an isolated field, but in connection with other fiel...
Index Medicus
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Ever Yours
In addition to his many remarkable paintings and drawings, Vincent van Gogh (1853-1890) left behind a fascinating and voluminous body of correspondence. This highly accessible book includes a broad selection of 265 letters, from a total of 820 in existence, that focus on Van Gogh’s relentless quest to find his destiny, a search that led him to become an artist; the close bond with his brother Theo; his fraught relationship with his father; his innate yearning for recognition; and his great love of art and literature. The correspondence not only offers detailed insights into Van Gogh’s complex inner life, but also re-creates the world in which he lived and the artistic avant-garde that was taking hold in Paris. The letters are accompanied by a general introduction, historic family photographs, and reproductions of 87 actual pages of letters that contain sketches by Van Gogh. Selected from the critically acclaimed 6-volume set of letters published by the Van Gogh Museum in 2009, Ever Yours is the essential book on Van Gogh’s letters, which every art and literature lover needs to own.
Extracellular Vesicles in Cardiovascular and Metabolic Diseases
This book provides the latest research progress on Extracellular vesicles (EVs) in cardiovascular and metabolic diseases. EVs are small bilayer lipid membrane vesicles released by cells and function for intercellular communication. Increasing evidence has shown that EVs play crucial roles in cardiovascular and metabolic diseases, which seriously threaten human health worldwide. The book contains four sections: 1) Extraction Methods; 2) EVs in Cardiovascular Diseases; 3) EVs in Metabolic Diseases; and 4) Therapeutic Implications. This book is useful for biologists, cardiologists, cardiovascular surgeons, endocrinologists, internists, nurses, undergraduate and graduate students in medicine and cell biology, and others interested in cardiovascular and metabolic medicine.
Guy Debord, the Situationist International, and the Revolutionary Spirit
Winner of the 2020 Choice Outstanding Academic Title Award Guy Debord, the Situationist International, and the Revolutionary Spirit presents a history of the two avant-garde groups that French filmmaker and subversive strategist Guy Debord founded and led: the Lettrist International (1952–1957) and the Situationist International (1957–1972). Debord is popularly known for his classic book The Society of the Spectacle (1967), but his masterwork is the Situationist International (SI), which he fashioned into an international revolutionary avant-garde group that orchestrated student protests at the University of Strasbourg in 1966, contributed to student unrest at the University of Nanterre ...
Assessing and Stimulating a Dialogical Self in Groups, Teams, Cultures, and Organizations
This book presents 9 theory-based and practice-oriented methods for assessing and stimulating a multi-voiced dialogical self in the context of groups, teams, cultures, and organizations. All of these methods are based on Dialogical Self Theory. The book deals with the practical implications of this theory as applied in the areas of coaching, training, and counselling. A number of chapters focus on the process of positioning and dialogue on the level of the self, while other chapters combine self-processes with group work, and still others find their applications in leadership development and team-work in organizations. For each of the nine methods, the chapters present theory, method, case-s...
