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Primary Immunodeficiency Disorders: A Historic and Scientific Perspective provides a complete historical context that is crucial for students and researchers concerned with primary immunodeficiency. When researchers have a poor understanding of the way we arrived where we are in research, they can miss important points about a disease, or miss out on how to approach new diseases. This historical knowledge of research can assist greatly by showing how it was done in the past, demonstrating the successes and failures, so that it can be done better in the future. This book provides an understanding of the process going from clinical problem to lab and back to the clinic, based on historical exp...
Sleep was taking over Anna’s life. Despite multiple alarm clocks and powerful stimulants, the young Atlanta lawyer could sleep for thirty or even fifty hours at a stretch. She stopped working and began losing weight because she couldn’t stay awake long enough to eat. Anna’s doctors didn't know how to help her until they tried an oddball drug, connected with a hunch that something produced by her body was putting her to sleep. The Woman Who Couldn’t Wake Up tells Anna’s story—and the broader story of her diagnosis, idiopathic hypersomnia (IH), a shadowy sibling of narcolepsy that has emerged as a focus of sleep research and patient advocacy. Quinn Eastman explores the science arou...
This book covers the history of the World Federation of Neurology (WFN), the international society for the clinical neurosciences, from its founding in Brussels in 1957 to the present day.
Cílem této knihy je podat informace k lepšímu pochopení fenoménu laterality i jeho diagnostiky. Veškeré informace jsou předkládány s ohledem na validizaci nových diagnostických metod určujících motorické projevy laterality u adolescentů a dospělých ve věku od 18 do 60 let a dětí od 8 do 10 let. Kromě toho je v této monografii také navržen nový možný přístup k určení laterality horní končetiny pomocí vztahu mezi mozečkovou dominancí a výkonností ruky.
This is a comprehensive rehabilitation textbook emphasizing functional approach based on the aspects of the Prague School of Rehabilitation (www.rehabps.com), which was developed by Professors Vojta, Janda, Lewit and others. The publication is divided into general and special sections. The diagnostic section describes in detail clinical evaluation approaches for the musculoskeletal system, testing and assessment of a motor and sensory involvement and limitations in the activities of daily living. The text also includes psychological assessment in rehabilitation of painful conditions, functional laboratory assessments and functional assessment using imaging methods. In the general section of ...
This book provides extensive data on the more common and many of the more rare congenital and hereditary syndromes that manifest in the nervous system and skin. Though often complex and multi-systemic, these disorders can frequently be diagnosed using a combination of simple visual inspection and sound clinical expertise. Drawing on fully referenced information from thousands of articles, the international editorial team has prepared a comprehensive overview that includes historical perspectives, clinical features, the pathogenesis, and diagnostic and therapeutic strategies. In addition, it addresses the biochemical, molecular, and genetic basis of the disorders. The book is divided into fou...
Parkinsonism of various types has long been a debilitating and cruel affliction for significant numbers of people, and even today the cure remains elusive. The present volume explores the colorful and sometimes alarming history of the attempts to provide at least some relief from the symptoms of this disorder, commencing with interesting reports from ancient India and medieval Europe and continuing until the present time. Especial attention is devoted to L-DOPA therapy, still the leading pharmacological approach to the disorder more than forty years after its first application, and its place in the development of neurochemistry. But the employment of solanaceous plant alkaloid-based therapie...
A Historical Perspective on Evidence-Based Immunology focuses on the results of hypothesis-driven, controlled scientific experiments that have led to the current understanding of immunological principles. The text helps beginning students in biomedical disciplines understand the basis of immunologic knowledge, while also helping more advanced students gain further insights. The book serves as a crucial reference for researchers studying the evolution of ideas and scientific methods, including fundamental insights on immunologic tolerance, interactions of lymphocytes with antigen TCR and BCR, the generation of diversity and mechanism of tolerance of T cells and B cells, the first cytokines, t...
Includes section, "Recent book acquisitions" (varies: Recent United States publications) formerly published separately by the U.S. Army Medical Library.