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Protein Phosphorylation in Health and Disease
This volume explores some of the most exciting recent advances in basic research on protein phosphorylation in health and disease and how this knowledge is leading to advances in the various fields. Contributions from leading authorities Informs and updates on all the latest developments in the field
The JNK Signaling Pathway
Signal transduction is one of the most exciting research areas in modern biology as it deals with how information flows from the extracellular environment into a living cell to change its metabolism, genotype and phenotype. With the completion of the genomes of human and several other species, it becomes even more important to elucidate the molecul
Human Tumor-Derived p53 Mutants: A Growing Family of Oncoproteins
TP53 gene mutations are present in more than half of all human cancers. The resulting proteins are mostly full-length with a single amino acid change and are abundantly expressed in cancer cells. Some of the mutant p53 proteins gain oncogenic functions (GOF) through which it actively contribute to the aberrant cell proliferation, increased resistance to apoptotic stimuli and ability to metastasize. Gain of function mutant p53 proteins can transcriptionally regulate the expression of a large plethora of target genes. This mainly occurs through the formation of oncogenic transcriptional competent complexes that include mutant p53 protein, known transcription factors, posttranslational modifier...
Japanese Fashion
This book examines the entire sweep of Japanese clothing history, from the sophisticated fashion systems of late-Edo period kimonos to the present day, providing possible theories of how Japan made this fashion journey and linking current theories of fashion to the Japanese example. The book is unique in that it provides the first full history of the last two hundred years of Japanese clothing. It is also the first book to include Asian fashion as part of global fashion as well as fashion theory. It adds a hitherto absent continuity to the understanding of historical and current fashion in Japan, and is pioneering in offering possible theories to account for that entire history. By providing an analysis of how that entire history changes our understanding of the way fashion works this book will be an essential text for all students of fashion and design.
Per Jacobsson Lecture
The future of finance, and in particular saving it from a popular backlash against the global financial crisis and related crisis management policies, has become a matter of great concern. In this brochure, which presents in written form a lecture from the Per Jacobsson Foundation’s lecture series, former Reserve Bank of India Governor Y. V. Reddy explores three interrelated issues of particular concern to central bankers in the search for good finance for the future: how to ensure that the financial sector serves the society better, how to integrate financial sector policies better with national economic policies, and how to ensure that the financial industry functions as a means and not as an end in itself. The question-and-answer session following the lecture is also included in the brochure.
100 Inspiring Rafflesians, 1823-2003
This proceedings volume contains results presented at the Sixth International Workshop on Data Analysis in Astronomy - "Modeling and Simulation in Science" held on April 15-22, 2007, at the Ettore Majorana Foundation and Center for Scientific Culture, Erice, Italy. Recent progress and new trends in the field of simulation and modeling in three branches of science - astrophysics, biology, and climatology - are described in papers presented by outstanding scientists. The impact of new technologies on the design of novel data analysis systems and the interrelation among different fields are foremost in scientists' minds in the modern era. This book therefore focuses primarily on data analysis methodologies and techniques.
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Recent Advances in Computer Science and Information Engineering
CSIE 2011 is an international scientific Congress for distinguished scholars engaged in scientific, engineering and technological research, dedicated to build a platform for exploring and discussing the future of Computer Science and Information Engineering with existing and potential application scenarios. The congress has been held twice, in Los Angeles, USA for the first and in Changchun, China for the second time, each of which attracted a large number of researchers from all over the world. The congress turns out to develop a spirit of cooperation that leads to new friendship for addressing a wide variety of ongoing problems in this vibrant area of technology and fostering more collaboration over the world. The congress, CSIE 2011, received 2483 full paper and abstract submissions from 27 countries and regions over the world. Through a rigorous peer review process, all submissions were refereed based on their quality of content, level of innovation, significance, originality and legibility. 688 papers have been accepted for the international congress proceedings ultimately.
