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This innovative study charts the beginnings, history and fate of Interferon - one of modern medicine's most famous and infamous drugs. Interferon is part of the medical profession's armoury against viral infection, cancer and MS. The story of its development and use is one of survival in the face of remarkable cycles of promise and disappointment as a miracle drug. By telling this story, Toine Pieters' book provides insight into the research, manufacture, and marketing of new bio-molecules that mark modern medical science. Pieters' closely argued book adopts a multi-disciplinary approach in seeking to trace the extraordinary voyage of interferon. Through the lens of interferon's voyage, the ...
After Fidel Castro came to power in 1959, his second declaration, after socialism, was that Cuba would become a leader in international science. In biotechnology he would be proven right and, today, Cuba counts a meningitis B vaccine and cutting-edge cancer therapies to its name. But how did this politically and geographically isolated country make such impressive advances? Drawing on a unique ethnography, and blending the insights of anthropology, sociology, and geography, The Cuban Cure shows how Cuba came to compete with U. S. pharmaceutical giants—despite a trade embargo and crippling national debt. In uncovering what is distinct about Cuban biomedical science, S. M. Reid-Henry examine...
The main purpose of the volume Psychiatry and Biological Factors is to provide a comprehensive, state-of-the-art overview of the current research linked essentially to virus infections, immunity functions, and mental diseases. In recent years substantial advances have been registered in the physiopathol ogy of mental and neurological disorders. As a result, partial control of certain psychoses, anxiety syndromes, epilepsy, and Parkinson's disease is now possible. However, despite progress in biomedical research, numerous mental and neuro logical disorders afflict up to 15% of all individuals and little is known about the causes, prevention, and treatment of these diseases. Several epidemiolo...
The extraordinary account of the Cuban people’s struggle for survival in a post-Soviet world In the aftermath of the fall of the Soviet Union, Cuba faced the start of a crisis that decimated its economy. Helen Yaffe examines the astonishing developments that took place during and beyond this period. Drawing on archival research and interviews with Cuban leaders, thinkers, and activists, this book tells for the first time the remarkable story of how Cuba survived while the rest of the Soviet bloc crumbled. Yaffe shows how Cuba has been gradually introducing select market reforms. While the government claims that these are necessary to sustain its socialist system, many others believe they herald a return to capitalism. Examining key domestic initiatives including the creation of one of the world’s leading biotechnological industries, its energy revolution, and medical internationalism alongside recent economic reforms, Yaffe shows why the revolution will continue post-Castro. This is a fresh, compelling account of Cuba’s socialist revolution and the challenges it faces today.
The series of volumes entitled Biological Responses in Cancer: Progress toward Potential Applications provides information on approaches through which the interaction between neoplastic and normal cells may be modified. Each annual volume contains contributions in areas where significant prog ress has been made. Topics to be dealt with include immunologic and host defense systems, control mechanisms of cell and population growth, cell differentiation, and cell transformation. The regulatory mechanisms controlling the interactions between normal and tumor cells may be immunologic in nature or they may relate to diverse biological characteristics of tumor and normal cells and their response to...
Advances in Virus Research
Cancer is a broad group of diseases involving unregulated cell growth with elevated death rates as more people live in old age with mass lifestyle changes occurring in the world. The causes of cancer are diverse, complex, and still only partially understood. The chances of surviving the disease vary remarkably by the type and location of the malignancy and the extent of disease at the start of treatment. Early cancer detection is proving to be a valid approach. Cancer can be detected in a number of ways, including the presence of certain signs and symptoms, screening tests, or medical imaging. Cancer therapy is dynamically changing and revision and change in patient management is constant as...
Recombinant protein drugs are intimately associated with the impressive success story of the Biotech Industry during the past thirty years, some of them belonging to the most successful pharmaceutical products. More than thirty different proteins are available for a variety of clinical applications, over 300 proteins are presently being evaluated in clinical trials. In this new volume of the MDT series, historical, technical and clinical aspects of recombinant protein drug discovery and development are presented, covering past, present and future highlights. Leading scientists and co-founders of early Biotech companies describe technical breakthroughs and the fascinating story of pioneering discoveries, as well as the long way of translating them into products and business. Therefore, this book represents an exciting documentation of the beginning of a new era in the pharmaceutical industry. In addition, scientists from basic research, clinic and industry actively involved in new developments discuss...
"Combining the molecular, clinical, and historical aspects of virology, Understanding Viruses is a textbook for the modern undergraduate virology course. The text provides an introduction to human viral diseases. Additional chapters on viral diseases of animals; the history of clinical trials, gene therapy, and xenotransplantation; prions and viroids; plant viruses; and bacteriophages add to the coverage."--Jacket.