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Realtime Analysis of Large-Scale Data
In photon science more and more data are taken. It is not possible anymore to store and process all data offline. In this book, we explore strategies for handling this large amount of data. A neural network as well as techniques from image processing are used to efficiently categorize and select useful data. We also indicate why many sophisticated algorithms cannot be used in this context. In addition, a prototype for data selection is presented, discussed, and benchmarked.
X-Ray Free-Electron Laser
This book is a printed edition of the Special Issue "X-Ray Free-Electron Laser" that was published in Applied Sciences
Vem är hon
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Current Topics in Microbiology and Immunology
The expression of many bacterial genes adapts itself in an almost in stantaneous and reversible way to specific environmental changes. More specifically, the concentration of a number of metabolites, a function of the amounts of enzymes involved in their synthesis or degradation, in turn retroacts on the rate of synthesis of these enzymes. The genetic bases for this regulation were established by JACOB and MONOD (1961). These authors also showed how the known elements of these regulatory mechanisms could be connected into a wide variety of circuits endowed with any desired degree of stability, in order to account for essentially irreversible processes like differentiation (MONOD and JACOB, 1...
Combat Crew
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Neuroimaging I
Until recent advents in neuroimaging, the brain had been inaccessible to in vivo visualization, short of neurosurgical procedures or some unfortunate traumatic exposure. It is a tribute to the early contributors to clinical neuroscience that through what, by today's standards, would be deemed extremely crude measure ments, advancements in understanding brain function were made. For example, the theories of higher cortical functions of the brain by Aleksandr Luria or Hans-Lukas Teuber in the 1950s were essentially based on military subjects who sustained traumatic head wounds during World War II. These researchers could inspect the patient and determine where penetrating entrance and exit wou...
Base Excision Repair Pathway, The: Molecular Mechanisms And Role In Disease Development And Therapeutic Design
This book will serve as the preeminent text book on the topic of 'base excision repair', a key DNA repair pathway that protects cells from most spontaneous forms of DNA damage, including oxidative lesions that arise both in the nuclear and mitochondrial genomes. The book, which includes contributions from many of the world leaders in the field, provides a detailed description of the molecular mechanisms of base excision repair, as well as its emerging relationship to epigenetic regulation, the aging process and human disease, such as cancer susceptibility, immunological defects and neurological disorders. The book will also cover the state-of-the-art technologies being developed to assess base excision repair capacity among individuals in the population, in addition to the strategies being employed to target base excision repair as part of therapeutic paradigms to eradicate disease, namely cancer.This book represents one of the most extensive efforts to date to cover the topic of 'base excision repair'. It includes chapters by many of the most established investigators in the field, from all over the world.
