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In this volume, the contributing authors from top labs involved in stem cell theranostics share the latest advances in the field of stem cell research. The book covers many aspects of stem cell-based therapy and the progress made toward stem cell therapy for liver, ocular, and cardiovascular diseases as well as cancer. This volume serves as a continuation of Prof. Khawaja Husnain Haider’s previously edited books pertaining to stem cells-based therapnostics. This is an ideal book for researchers involved in drug development as well as regenerative medicine and stem cell-based therapy. The secondary audience includes graduate and postgraduate medical students, doctors, cellular pharmacology, drug industry, and researchers involved in using stem cells as ex-vivo disease models for drug development.
This book is a continuum of the first two books published in the STEM CELLS series entitled "Stem Cells: From Drug to Drug Discovery" and "Stem Cells: From Hype to Real Hope" which were published in 2017 and 2019, respectively. The scope of the book encompasses a wide range of topics with a latitude from adult stem cells to pluripotent stem cells in regenerative medicine either alone or as part of the combinatorial therapeutic intervention approach as "drug" besides their application as tools (disease model) during drug development process. Written by a leading group of researchers, the book encompasses experimental to clinical aspects of stem/progenitors cells, their biology, and characteristics.
Stem cell based therapy is a 21st century approach of therapeutic intervention which epitomizes a shift from conventional symptomatic treatment strategy to addressing the root cause of the disease process. This book is a compilation of the experience of experts involved in the cutting edge area of research, describing the use of stem cells both as therapeutic interventions and as disease model during drug development.
The handbook comprehensively reviews the therapeutic potential of stem cells and stem cell secretome-based cell-free strategies in regenerative medicine. The chapters in section I and section II respectively discuss the diverse applications of mesenchymal stem cells and non- mesenchymal stem cells, including skeletal myoblasts, endothelial progenitor cells, adipose tissue-derived stem cells, induced pluripotent stem cells, and neuronal stem cells in myocardial repair, inflammatory bowel disease, cognitive deficits, wound healing, retinal disorders, and COVID-19. The subsequent chapters in section IIIprimarily focused on the fast-emerging cell-free therapy approach in regenerative medicine fo...
The book highlights the therapeutic applications of various stem cells, and introduces readers to thymus stem cells and their applications in the reconstitution of thymic structure and function. It also discusses the significant role of mesenchymal stem cells (MSCs) in the treatment of autoimmune diseases and the use of MSC-derived exosomes in cell-free therapy. Moreover, it explores the application of hematopoietic stem cells in the vasculoprotection of the ischemially injured heart. Further topics include the regenerative potential of ovarian germline stem cells and the significance of endometrial stem cells in the pathogenesis of female reproductive tract diseases. Lastly, the book addresses stem cells from perinatal tissues and their immunoregulatory and differentiation potentials, and summarizes new strategies for targeting cancer stem cells to treat tumors.
This book highlights the therapeutic potential of cell-free and cell-based therapies, including extracellular vesicles (EVs) and mesenchymal stem cell-derived exosomes across regenerative medicine. It explores their applications in liquid biopsies and tissue engineering. It is a useful resource for researchers of regenerative medicine.
This book is a compilation of the bench experience of leading experts from various research labs involved in the cutting edge area of research. The authors describe the use of stem cells both as part of the combinatorial therapeutic intervention approach and as tools (disease model) during drug development, highlighting the shift from a conventional symptomatic treatment strategy to addressing the root cause of the disease process. The book is a continuum of the previously published book entitled "Stem Cells: from Drug to Drug Discovery" which was published in 2017.
The present book Cardiac Functioning, Disorders, Challenges and Therapies is aimed to create a combined collection of study material for medical professionals, researchers and students to understand outcome of recent cardiac researchers at a glance. The chapters have been written by the renowned and internationally established cardiologists. The book covers many topics of current interest to cardiologists and physiologists ranging from cardiac conducting system to recent therapeutic approaches and researches made in the area of heart treatment therapies.
This book is an impressive compilation of contributions on the hot topic of cardiac stem cell therapy from leading groups all over the world. In the assembly of chapters, a structured approach is adopted; starting from the clinician's perspective, all developments in both the experimental and clinical research areas are covered. This journey will take the reader from the bench-top to the bedside, with all chapters written by leading authorities in their respective fields, including data still in press with medical journals. So, beyond being excellent as an overall update for scientists in the field of cardiac stem cell therapy, this book will likely prove an indispensable tool for every budding scientist considering a research project within this field.