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India’s Founding Moment
An Economist Best Book of the Year How India’s Constitution came into being and instituted democracy after independence from British rule. Britain’s justification for colonial rule in India stressed the impossibility of Indian self-government. And the empire did its best to ensure this was the case, impoverishing Indian subjects and doing little to improve their socioeconomic reality. So when independence came, the cultivation of democratic citizenship was a foremost challenge. Madhav Khosla explores the means India’s founders used to foster a democratic ethos. They knew the people would need to learn ways of citizenship, but the path to education did not lie in rule by a superior clas...
High Noon
In 1982, a little upstart named Sun was making waves in the high-tech industry with its groundbreaking workstation technology, even as early competitors dismissed the company as not worth losing sleep over. Since then, Sun Microsystems has become a formidable presence in the industry, making its own rules and taking no prisoners, and is currently poised to reach the highest point of its ascendancy--the challenge of Microsoft's dominance over the future of computing. The driving force behind this once fledgling company is a man who has been described as brash, unconventional, ambitious, forward-looking, and sometimes even his own worst enemy. Scott McNealy turned Sun into the multibillion-dol...
Comprehensive Natural Products II
This work presents a definitive interpretation of the current status of and future trends in natural products—a dynamic field at the intersection of chemistry and biology concerned with isolation, identification, structure elucidation, and chemical characteristics of naturally occurring compounds such as pheromones, carbohydrates, nucleic acids, and enzymes. With more than 1,800 color figures, Comprehensive Natural Products II features 100% new material and complements rather than replaces the original work (©1999). Reviews the accumulated efforts of chemical and biological research to understand living organisms and their distinctive effects on health and medicine Stimulates new ideas am...
The Holy Grail of Investing
#1 NEW YORK TIMES BESTSELLER Tony Robbins returns with the final book in his financial freedom trilogy by unveiling the power of alternative investments. Robbins, and renowned investor Christopher Zook, take you on a journey to interview a dozen of the world’s most successful investors in private equity, private credit, private real estate, and venture capital. They share their favorite strategies and insights in this practical guidebook. For decades, trillions of dollars in “smart money” has been making outsized returns using private equity, private credit, venture capital and other alternative investments. Robbins teams up with renowned private equity investor Christopher Zook, found...
Exploiting Chemical Diversity for Drug Discovery
Conceptual and technological advances in chemistry and biology have transformed the drug discovery process. Evolutionary pressure among the diverse scientific and engineering disciplines that contribute to the identification of biologically active compounds has resulted in synergistic improvements at every step in the process. Exploiting Chemical Diversity for Drug Discovery encompasses the many components of this transformation and presents the current state-of-the-art of this critical endeavour. From the theoretical and operational considerations in generating a collection of compounds to screen, to the design and implementation of high-capacity and high-quality assays that provide the mos...
Indianizing India
This book presents a comprehensive portrait of how Indians conceived of the idea of India. It highlights the diverse traditions and intellectual threads that contributed to the making of vibrant democracy. The book: • Examines the different ideas of India through 14 eminent Indian thinkers: Mahatma Gandhi, Rabindranath Tagore, Dayanand Saraswati, VD Savarkar, Savitribai Phule, Pandita Ramabai, Maulana Azad, Jawaharlal Nehru, BR Ambedkar, Subhash Chandra Bose, Aurobindo Ghosh, Sarala Devi Chaudhurani and MA Jinnah; • Highlights how ancient and modern intellectual discourses coalesced with the aspirations of ordinary Indians under the yoke of colonialism; • Challenges colonial constructs and linear approaches to studying India. Accessibly written, this book is essential reading for students and researchers of Indian political thought, modern history, political science, and South Asian studies.
Drug Discovery from Nature
This book is unique in covering the present status and future potential of natural products in drug discovery. It provides readers with recent information regarding the impact on drug discovery, development and strategies, technical and automation aspects, and methods based on biochemistry as well as molecular biology, highlighting compounds from natural sources. Special emphasis is placed on the various strategies to gain access to natural compounds and combinatorial approaches by making use of both synthetic and biological methods.
Biosynthesis
This book is the second of two volumes that deal with discovery of chemical pathways of biosynthesis of natural products (secondary metabolites). The first volume covered the use of isotopes in biosynthetic research and the formation of enzyme cofactors and reduced polyketides. This second volume describes biosynthesis of aromatic (unreduced) polyketides, enzymes responsible for cyclization of terpenoids (isoprenoids), and biochemical generation of selected classes of alkaloids (prenylated tryptophan, tropane, pyrrolizidine). Knowledge of the pathways and the techniques to elucidate them opens the door to combinatorial biosynthesis as well as to the production of targeted pharmaceutical agents utilizing a combination of chemistry, molecular biology and protein biochemistry.
Handbook of Chiral Chemicals
As pharmaceutical companies look to develop single enantiomers as drug candidates, chemists are increasingly faced with the problems associated with this subclass of organic synthesis. "The Handbook of Chiral Chemicals, Second Edition" highlights the problems associated with the production of chiral compounds on a commercial scale. The handbook fir
