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Polymicrobial Diseases
Polymicrobial diseases, those involving more than one etiologic agent, are more common than is generally realized and include respiratory diseases, gastroenteritis, conjunctivitis, keratitis, hepatitis, periodontal diseases, multiple sclerosis, genital infections, intra -- abdominal infections, and pertussis.
Human Oral Mucosa
Human Oral Mucosa: Development, Structure and Function is a new text that reflects the considerable increase in knowledge of oral mucosa that has occurred in recent years. Our understanding of the structure of oral mucosa is now established at a molecular rather than a tissue or cellular level. This in turn has revealed a level of function that was previously not suspected, including a sophisticated barrier to the penetration of exogenous materials, and the synthesis of specific antimicrobial compounds, representing components of the innate immune system. There is also a growing realization of commonality in structure and function between regions of oral mucosa and the mucosae of the esophag...
Emerging Concepts in Bacterial Biofilms
The ability to form biofilms is a universal attribute of bacteria. Bacteria are able to grow on almost every surface, forming these architecturally complex communities. In biofilms, the cells grow in multicellular aggregates, encased in an extracellular matrix produced by the bacteria themselves. They impact humans in many ways, and can form in natural, medical and industrial settings. For example, the formation of biofilms on medical devices such as catheters or implants often results in difficult-to-treat chronic infections. This book focuses on emerging concepts in bacterial biofilm research, such as the different mechanisms of biofilm formation in Gram negative and Gram positive bacteria, and the burden of biofilm associated infections. It also highlights the various anti-biofilm strategies that can be translated to curb biofilm-associated infections and the escalation of antimicrobial resistance determinants.
Mammalian Host Defense Peptides
Cationic antimicrobial peptides are multifunctional peptides of the innate immune system, which not only act directly against microorganisms, but also signal between early and late immune responses and modulate inflammatory reposnes. The significance of these host defence peptides in combating infection and in host-microbe homeostasis has become increasingly clear, through advances made by microbiologists, biochemists, biophysicists, immunologists, molecular biologists, and a range of medical and pharmaceutical researchers. This book, drawing together contributions from leading scientists, reviews significant recent advances in our knowledge of mammalian antimicrobial peptides. In addition to providing up-to-date overviews of their structure, expression and biology, their multiple activities and interactions with microbial populations as well as their potential application as novel therapeutic agents are summarized. Chapters describing developments using animal models and investigations of the roles of these host defence peptides in microbial infections are complemented by chapters addressing their mechanisms of action and of microbial resistance.
TEXTBOOK OF BIOCHEMISTRY, BIOTECHNOLOGY, ALLIED AND MOLECULAR MEDICINE
The Fourth Edition of the compendium pools together the knowledge and experience of experts from all over the world, who are engaged in teaching and research in the field of biochemistry, medical sciences and allied disciplines. Comprising 20 sections, the present edition of the book has been substantially revised incorporating the latest research and achievements in the field. Beginning appropriately with chemical architecture of the living systems, role and significance of biochemical reactions, organization of specialised tissues, and importance of food and nutrition, the book explores beyond traditional boundaries of biochemistry. The knowledge of various organ systems has been expanded ...
Lipids and Essential Oils as Antimicrobial Agents
Lipids and essential oils have strong antimicrobial properties — they kill or inhibit the growth of microbes such as bacteria, fungi, or viruses. They are being studied for use in the prevention and treatment of infections, as potential disinfectants, and for their preservative and antimicrobial properties when formulated as pharmaceuticals, in food products, and in cosmetics. Lipids and Essential Oils as Antimicrobial Agents is a comprehensive review of the scientific knowledge in this field. International experts provide summaries on: the chemical and biological properties of lipids and essential oils use of lipids and essential oils in pharmaceuticals, cosmetics and health foods antimic...
Ultrastructural Pathology
Ultrastructural Pathology
