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This book describes in detail the various techniques of minimally invasive thyroidectomy that have emerged in recent years and presents the new supportive equipment, including intraoperative monitoring and energy devices. In addition, the basic preoperative techniques that are a prerequisite to successful thyroidectomy are covered, and individual chapters are devoted to complications, outcomes, and post-thyroidectomy quality of life. Important related topics are also discussed, including guidelines for managing papillary and medullary thyroid cancer and the surgical management of metastatic lymph nodes. Both the editors and the authors are internationally renowned experts, and they include the founders of several of the techniques described. The up-to-date text is supplemented by many color pictures and medical illustrations, making the book very user-friendly and ideal for the busy surgeon or endocrinologist who is interested in the management of thyroid diseases.
Minimally Invasive and Robotic Thyroid and Parathyroid Surgery is the first textbook which includes a comprehensive review of both minimally invasive and robotic thyroid and parathyroid techniques. Over the last several years there has been a rapid expansion in the number of different surgical approaches available to patients undergoing thyroid and parathyroid surgery. This book consolidates these in one source and focuses on both the philosophy and techniques of these procedures. For thyroid surgery, the text covers the full range of minimally invasive procedures and several of the most widely adopted remote access techniques. Several related procedures are also discussed, including minimal...
There hasn’t been a better time to be a drug developer for immune-based therapies than the past couple of decades. We have seen an explosion in immune-based therapies for cancer, autoimmune and infectious diseases, metabolic diseases and diseases and disorders of the nervous system. The modalities of these immune-based therapies span small molecules, biologics, and gene and cell therapeutic approaches. Significant advances have been made in optimizing drug design for its specificity for the target, characterizing the mode of action in in vitro assays, and ensuring safety and manufacturability. However, an area of challenge that remains is identifying animal models for evaluating efficacy and pharmacokinetics/pharmacodynamics relationship that are predictive of drug effects in humans. Discussion on this topic is warranted as examples of failures of translation from animal models to humans provide us an opportunity to learn more about human biology.
The first edition of Robotic Surgery was written only a decade after the introduction of robotic technology. It was the first comprehensive robotic surgery reference and represented the early pioneering look ahead to the future of surgery. Building upon its success, this successor edition serves as a complete multi-specialty sourcebook for robotic surgery. It seeks to explore an in-depth look into surgical robotics and remote technologies leading to the goal of achieving the benefits of traditional surgery with the least disruption to the normal functions of the human body. Written by experts in the field, chapters cover the fundamental principles of robotic surgery and provide clear instruc...
This book provides a comprehensive, state-of-the art review of this field, and will serve as a valuable resource for clinicians and researchers with an interest in the management of thyroid nodules and cancer, including both surgeons and endocrinologists. The book reviews new data about risk factors for nodular disease and cancer, details the management of toxic and non-toxic benign thyroid nodular disease, discusses controversies in the management of indeterminate thyroid nodules and cancer, and reviews the latest data on use of molecular testing for diagnosis and prognosis. Lastly, the book reviews the management of difficult-to-treat thyroid cancers. Management of Thyroid Nodules and Differentiated Thyroid Cancer: A Practical Guide will serve as a useful resource for physicians and researchers dealing with, and interested in thyroid nodular disease and cancer. It will provide a concise yet comprehensive summary of the current status of the field that will help guide patient management and stimulate investigative efforts. All chapters are written by experts in their fields and include the most up to date scientific and clinical information.
This is the first book to present the idea of using Industry 4.0 and smart manufacturing in the microalgae industry for environmental biotechnology. It provides the latest developments on microalgae for use in environmental biotechnology, explains process analysis from an engineering point of view, and discusses the transition to smart manufacturing and how state of the art technologies can be incorporated. It covers applications, technologies, challenges, and future perspectives. • Showcases how Industry 4.0 can be applied in algae industry • Covers new ideas generated from Industry 4.0 for Industrial Internet of Things (IIoT) • Demonstrates new technologies invented to cater to Industry 4.0 in microalgae • Features worked examples related to biological systems Aimed at chemical engineers, bioengineers, and environmental engineers, this is an essential resource for researchers, academics, and industry professionals in the microalgae biotechnology field.
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Part of a four-volume set, this book constitutes the refereed proceedings of the 7th International Conference on Computational Science, ICCS 2007, held in Beijing, China in May 2007. The papers cover a large volume of topics in computational science and related areas, from multiscale physics to wireless networks, and from graph theory to tools for program development.