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Index Medicus
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Adenosine Receptors in Health and Disease
Since their discovery approximately 25 years ago, adenosine receptors have now emerged as important novel molecular targets in disease and drug discovery. These proteins play important roles in the entire spectrum of disease from inflammation to immune suppression. Because of their expression on a number of different cell types and in a number of different organ systems they play important roles in specific diseases, including asthma, rheumatoid arthritis, Parkinson’s disease, multiple sclerosis, Alzheimer’s disease, heart disease, stroke, cancer, sepsis, and obesity. As a result of intense investigations into understanding the molecular structures and pharmacology of these proteins, new molecules have been synthesized that have high specificity for these proteins and are now entering clinical trials. These molecules will define the next new classes of drugs for a number of diseases with unmet medical needs.
Proceedings of the 4th International Conference on Performance Based Design in Earthquake Geotechnical Engineering (Beijing 2022)
The 4th International Conference on Performance-based Design in Earthquake Geotechnical Engineering (PBD-IV) is held in Beijing, China. The PBD-IV Conference is organized under the auspices of the International Society of Soil Mechanics and Geotechnical Engineering - Technical Committee TC203 on Earthquake Geotechnical Engineering and Associated Problems (ISSMGE-TC203). The PBD-I, PBD-II, and PBD-III events in Japan (2009), Italy (2012), and Canada (2017) respectively, were highly successful events for the international earthquake geotechnical engineering community. The PBD events have been excellent companions to the International Conference on Earthquake Geotechnical Engineering (ICEGE) series that TC203 has held in Japan (1995), Portugal (1999), USA (2004), Greece (2007), Chile (2011), New Zealand (2015), and Italy (2019). The goal of PBD-IV is to provide an open forum for delegates to interact with their international colleagues and advance performance-based design research and practices for earthquake geotechnical engineering.
Microplastics in the Environment
Authoritative reference addressing the characteristics, technologies, and solutions surrounding the most concerning environmental pollutant Microplastics in the Environment delivers a systematic and in-depth overview of microplastics generation mechanisms, risk prevention, and control solutions. Written by a highly qualified academic with significant research experience in microplastic pollution treatment, green polymer material functionalization, and recycling of solid waste, Microplastics in the Environment explores sample topics including: Characteristics of microplastics, such as their large specific surface area and small size, resulting in the formation of composite contamination New m...
CRC Handbook of Organic Analytical Reagents
The Handbook of Organic Analytical Reagents, 2nd Edition, is an indispensable source book of physico-chemical properties, preparation, and analytical applications of the most commonly used organic reagents. Updated from the 1st Edition, this volume includes data on 40 new reagents (such as ultra-high sensitive azo dyes, fluorescent calcium indicators, and chromogenic crown ethers and porphyrin reagents), a new Reagent Index listing reagents according to the elements to be assayed, and completely updated references. Each entry contains information on synonyms, sources and methods of synthesis, analytical applications, complexation reactions and the properties of complexes, purification and purity of the reagent, and other regeants with a related structure. The Handbook of Organic Analytical Reagents, 2nd Edition, is an invaluable bench-side reference for professional analytical chemists and graduate students.
Protein Reviews
The aim of the Protein Reviews is to serve as a publication vehicle for review articles that focus on crucial current vigorous aspects of protein structure, function, evolution and genetics. The volumes will appear online before they are published in a printed book. Articles are selected according to their importance to the understanding of biological systems, their relevance to the unravelling of issues associated with health and disease or their impact on scientific or technological advances and developments. The chapters in volume 18 are authored by experts in the field. They deal with aspects of structure and/or biological activity of selected proteins. The chapters review current resear...
Yearbook of Intensive Care and Emergency Medicine
The Yearbook compiles the most recent, widespread developments of experimental and clinical research and practice in one comprehensive reference book. The chapters are written by well recognized experts in the field of intensive care and emergency medicine. It is addressed to everyone involved in internal medicine, anesthesia, surgery, pediatrics, intensive care and emergency medicine.
Purinergic Signalling and the Nervous System
In the first 20 years that followed the purinergic signalling hypothesis in 1972, most scientists were sceptical about its validity, largely because ATP was so well established as an intracellular molecule involved in cell biochemistry and it seemed unlikely that such a ubiquitous molecule would act as an extracellular signalling molecule. However, after the receptors for ATP and adenosine were cloned and characterized in the early 1990s and ATP was established as a synaptic transmitter in the brain and sympathetic ganglia, the tide turned. More recently it has become clear that ATP is involved in long-term (trophic) signalling in cell proliferation, differentiation and death, in development...
