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Progress in Medicinal Chemistry
This text is an unbound, binder-ready edition. Visualizing Psychology, Third Edition helps students examine their own personal studying and learning styles with several new pedagogical aids--encouraging students to apply what they are learning to their everyday lives while offering ongoing study tips and psychological techniques for mastering the material. Most importantly, students are provided with numerous opportunities to immediately access their understanding.
On the threshold of an exciting new era for acute stroke diagnosis and treatment, the Third International Symposium on Thrombolytic Therapy in Acute Ischemic Stroke was held in Nara, Japan, in April 1994. The symposium brought together some 200 basic and clinical scientists for presentations and discussions of issues vital to the understanding of thrombolytic therapy. This volume compiles the major presentations of the symposium, with attention to applications of new diagnostic measures such as diffusion and perfusion MRI, contrast-enhanced transcranial Doppler and angioscopy. Other presentations examine the mechanisms of ischemia/reperfusion injury, hemorrhagic transformation, and reocclusion, with reviews of recent developments in thrombolytic agents. The proceedings of the symposium will be of special interest to researchers, physicians, and students in the fields of neurology, neurosurgery, and nuclear medicine, as well as those in pharmacology, critical care medicine, and related fields.
The global energy scenario is undergoing an unprecedented transition. In the wake of enormous challenges—such as increased population, higher energy demands, increasing greenhouse gas emissions, depleting fossil fuel reserves, volatile energy prices, geopolitical concerns, and energy insecurity issues—the energy sector is experiencing a transition in terms of energy resources and their utilization. This modern transition is historically more dynamic and multidimensional compared to the past considering the vast technological advancements, socioeconomic implications and political responses, and ever-evolving global policies and regulations. Energy insecurity in terms of its critical dimen...
Neurology is one of the most fascinating areas of medical science and general biology but it has traditionally been limited to some dedicated aspects only. However, modern neuroscience has embarked on exciting and diverse frontiers related to the causes, diagnosis, and treatment of neurological disease and nowadays, neurology has become multidisciplinary. There are many books available that deal with only one key concept of neurology but a book with a multidisciplinary approach is lacking so far. This book emphasizes all the conventional and applied divisions associated with neurology in reference to medical physiology and general biology and covers all aspects to integrate the topics of int...
Clinical Trials in Neurology comprehensively tackles the methodology and design of clinical trials in neurological disease. A general section deals with the ethical aspects, drug development and regulatory requirements, basic trial designs and the statistics used. A diseases section tackles specific aspects of disorders, focusing on the relevant ethical issues, outcome variables and experience with large multicentre trials.
The declaration of the Republic of China in 1912 signalled an entirely new era. Not only did the revolution of 1911–12 bring about the fall of the Qing dynasty: it also brought an end to the entire series of dynasties that had marked Chinese history for over two millennia. Radical reforms since 1901 had culminated in the ending of the political status quo and the rejection of the very idea of empire. Drawing on the most recent historical research, Xavier Paulès provides a comprehensive account of the crucial but chaotic period that stretched from the founding of the Republic of China in 1912 to the civil war of 1945–9, which ended with the victory of the Chinese Communist Party (CCP) an...
Concurrent Engineering is based on the concept that different phases of a product life cycle should be conducted concurrently and initiated as early as possible within the Product Creation Process (PCP). Its main goal is to increase the efficiency and effectiveness of the PCP and reduce errors in the later stages, and to incorporate considerations for the full lifecycle, through-life operations, and environmental issues of the product. It has become the substantive basic methodology in many industries, and the initial basic concepts have matured and become the foundation of many new ideas, methodologies, initiatives, approaches and tools. This book presents the proceedings of the 24th ISPE I...
Atherosclerosis is the principal underlying cause of cardiovascular and cerebrovascular disease in people of the Western world. Cigarette smoking has been implicated in both the initiation and exacerbation of the atherosclerotic process. Data to support this implication derives primarily from epidemiologic studies where the relationship between the incidence of atherosclerosis in people who smoke cigarettes has been shown to have a strong correlation. There are few well established explanations for this phenomenon, and basic molecular, biochemical, and cellular mechanisms associated with smoking and the development of atherosclerosis remain both undefined and virtually unexplored. Even the e...