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Fundamentos da Organização do Trabalho Pedagógico dos professores de Educação Física da Rede Municipal de Castanhal-PA
Esta obra é uma adaptação da minha dissertação de mestrado em formato de livro que teve como objeto de estudo os fundamentos pedagógicos na Organização do Trabalho Pedagógico (OTP) dos professores de Educação Física nas séries finais do ensino fundamental na Rede Municipal de Castanhal-PA. Neste sentido, o livro analisa os fundamentos presentes na OTP dos professores de Educação Física das séries finais do ensino fundamental na Rede Municipal de Castanhal-PA. No que se refere à formação, a investigação mostrou que a maioria dos professores do Município de Castanhal possui pós-graduação em áreas fora do âmbito educacional e trabalha em outras localidades, acumuland...
Reinforcement Learning, second edition
The significantly expanded and updated new edition of a widely used text on reinforcement learning, one of the most active research areas in artificial intelligence. Reinforcement learning, one of the most active research areas in artificial intelligence, is a computational approach to learning whereby an agent tries to maximize the total amount of reward it receives while interacting with a complex, uncertain environment. In Reinforcement Learning, Richard Sutton and Andrew Barto provide a clear and simple account of the field's key ideas and algorithms. This second edition has been significantly expanded and updated, presenting new topics and updating coverage of other topics. Like the fir...
The VR Book
This is a strong foundation of human-centric virtual reality design for anyone and everyone involved in creating VR experiences. Without a clear understanding of the human side of virtual reality (VR), the experience will always fail. The VR Book bridges this gap by focusing on human-centered design. Creating compelling VR applications is an incredibly complex challenge. When done well, these experiences can be brilliant and pleasurable, but when done badly, they can result in frustration and sickness. Whereas limitations of technology can cause bad VR execution, problems are oftentimes caused by a lack of understanding human perception, interaction, design principles, and real users. This b...
mTOR in Human Diseases
The mechanistic target of rapamycin (mTOR) is a major signaling intermediary that coordinates favorable environmental conditions with cell growth. Indeed, as part of two functionally distinct protein complexes, named mTORC1 and mTORC2, mTOR regulates a variety of cellular processes, including protein, lipid, and nucleotide synthesis, as well as autophagy. Over the last two decades, major molecular advances have been made in mTOR signaling and have revealed the complexity of the events implicated in mTOR function and regulation. In parallel, the role of mTOR in diverse pathological conditions has also been identified, including in cancer, hamartoma, neurological, and metabolic diseases. Through a series of articles, this book focuses on the role played by mTOR in cellular processes, metabolism in particular, and highlights a panel of human diseases for which mTOR inhibition provides or might provide benefits. It also addresses future studies needed to further characterize the role of mTOR in selected disorders, which will help design novel therapeutic approaches. It is therefore intended for everyone who has an interest in mTOR biology and its application in human pathologies.
Diplomatic List
Directory of foreign diplomatic officers in Washington.
Food Safety Culture
Food safety awareness is at an all time high, new and emerging threats to the food supply are being recognized, and consumers are eating more and more meals prepared outside of the home. Accordingly, retail and foodservice establishments, as well as food producers at all levels of the food production chain, have a growing responsibility to ensure that proper food safety and sanitation practices are followed, thereby, safeguarding the health of their guests and customers. Achieving food safety success in this changing environment requires going beyond traditional training, testing, and inspectional approaches to managing risks. It requires a better understanding of organizational culture and ...
2004 IUCN Red List of Threatened Species
Applies Red List data to calculate a Red List Index.
Mitochondria and Cancer
Nearly a century of scientific research has revealed that mitochondrial dysfunction is one of the most common and consistent phenotypes of cancer cells. A number of notable differences in the mitochondria of normal and cancer cells have been described. These include differences in mitochondrial metabolic activity, molecular composition of mitochondria and mtDNA sequence, as well as in alteration of nuclear genes encoding mitochondrial proteins. This book, Mitochondria and Cancer, edited by Keshav K. Singh and Leslie C. Costello, presents thorough analyses of mitochondrial dysfunction as one of the hallmarks of cancer, discusses the clinical implications of mitochondrial defects in cancer, and as unique cellular targets for novel and selective anti-cancer therapy.
Microbial Approaches for Insect Pest Management
This book brings together specialized information on modern aspects of applied microbiology in pest management. In the last few decades, the humans have witnessed major advancements in Life Sciences, as a result several new and powerful tools and techniques have evolved. This has led to great advancements in microbial nutrition, genetics and their application in different fields. In modern era of biotechnology, the microbes have provided solutions to many of the human problems and necessities and thus serve as human and farmers’ friends. The microbes have proved to be successful tools for the pest management. Similarly, there has been much advancement in the field of molecular biology, whe...
