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Since publication of the first edition in 1995, there have been significant advances and understanding of chromatin structure and its relation to gene expression. These include a high-resolution structure of the nucleosome core, discovery of the enzymes and complexes that mediate histone acetylation and deacetylation, discovery of novel ATP-dependent chromatin remodeling complexes, new insights into nuclear organization and epigenetic silencing mechanisms. In light of these advances, Chromatin Structure and Gene Expression (2ed.) includes updated chapters and additional material that introduce new concepts in the process of gene regulation in chromatin.
Epigenetics pertains to the development of an organism from an undifferential cell, resulting in the successive formation and development of organs and parts that did not pre-exist in the fertilized egg. An exciting and stimulating volume which used the extensive knowledge of basic transcriptional control as a foundation to explore the more complex and interesting level at which genes can be regulated.
Discusses staphylococcus aureus bacteria and the infections they can cause, their diagnosis, treatment, and more.
How should we understand the fear and fascination elicited by the accounts of communicable disease outbreaks that proliferated, following the emergence of HIV, in scientific publications and the mainstream media? The repetition of particular characters, images, and story lines—of Patients Zero and superspreaders, hot zones and tenacious microbes—produced a formulaic narrative as they circulated through the media and were amplified in popular fiction and film. The “outbreak narrative” begins with the identification of an emerging infection, follows it through the global networks of contact and contagion, and ends with the epidemiological work that contains it. Priscilla Wald argues th...
Virtual English examines English language communication on the World Wide Web, focusing on Internet practices crafted by underserved communities in the US and overlooked participants in several Asian Diaspora communities. Jillana Enteen locates instances where subjects use electronic media to resist popular understandings of cyberspace, computer-mediated communication, nation and community, presenting unexpected responses to the forces of globalization and predominate US value systems. The populations studied here contribute websites, conversations and artifacts that employ English strategically, broadening and splintering the language to express their concerns in the manner they perceive as...
Witch Fulfillment: Adaptation Dramaturgy and Casting the Witch for Stage and Screen addresses the Witch as a theatrical type on twenty-first-century-North American stages and screens, seen through the lenses of casting, design, and adaptation, with attention paid to why these patterns persist, and what wishes they fulfil. Witch Fulfillment examines the Witch in performance, considering how actors embody iconic roles designated as witches (casting), and how dramaturgical choices (adaptation) heighten their witchy power. Through analysis of Witch characters ranging from Elphaba to Medea, classic plays such as The Crucible and Macbeth, feminist adaptations - including Sycorax, Obeah Opera, and Jen Silverman’s Witch - and popular culture offerings, like the Scarlet Witch and Jinkx Monsoon, this book examines the dramaturgical meanings of adapting and embodying witchy roles in the twenty-first century. This book contends that the Witch represents a crucial category of analysis for inclusive theatre and performance and will be of interest to theatre practitioners and designers, along with theatre, witchcraft, and occult studies scholars.
More than 90 authors and a handful of dedicated readers, have offered up their favorite recipes for this publication. Proceeds from the sale of the book will go toward care packages sent to U.S. troops.