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This volume reviews a broad range of recent developments in geriatric psychiatry. It includes chapters on health care services for the elderly, recognition of mental illness in older primary care patients, early diagnosis and treatment of Alzheimer's disease, the issue of competency, treatment of depression and agitation in dementia, electroconvulsive therapy for elderly patients, and the diagnosis and treatment of psychosis. The authors highlight important new developments in the clinical practice of geriatric psychiatry, making this volume a valuable addition to the literature on mental health care. This is the 76th issue of the quarterly journal New Directions for Mental Health Services.
The era of therapeutic nihilism in dementia has ended, with the emergence of agents for symptomatic treatment, those that delay the course of the disease or prevent the onset of dementia, and new methods to manage symptoms. With the expansion of therapies, there is a clear danger of being overwhelmed by the volume of data. This book is designed to collect this information, distil what is relevant and reliable, and present it in a format that is useful to clinicians who manage and treat people with dementia. The book is designed to bring together the latest, best and practical evidence on all aspects of management, from diagnosis and therapy to social and ethical considerations. The editors are all dynamic clinicians involved in the care of patients with dementia and the evaluation of therapies. Two of the editors are the leaders of the Cochrane Collaboration for the examination of therapies for dementia. There are no other books that take such a practical and problem-oriented or approach to the diagnosis and management of dementia. Furthermore none but this can be described as truely evidence-based.
What are the special considerations that apply to the diagnosis and treatment of depression in late life? The NIH Consensus Development Conference set out to address this topic in detail; Diagnosis and Treatment of Depression in Late Life presents their findings. Compiled by experts in the field, Diagnosis and Treatment of Depression in Late Life provides comprehensive studies on early-life depression versus late-life depression, the prevalence of depression in elderly people and the risk factors involved, issues regarding safe and effective treatment, the patterns for health service use, and the consequences of unrecognized or inadequately treated depression.
How current biomarkers are modernizing the diagnosis of Alzheimer's disease Expanding knowledge on genetic and epigenetic risk factors is rapidly enhancing our understanding of the complex molecular interactions and systems involved in the pathogenesis of Alzheimer's disease. In this publication, leading experts discuss emerging novel conceptual models of the disease along with advances in the development of surrogate markers that will not only improve the accuracy of diagnostic technologies but also improve the prospects of developing disease-modifying interventions. The novel framework of the disease presented here highlights research on biological markers as well as efforts to validate technologies for early and accurate detection. It also introduces notion of a complex systems dysfunction that extends beyond prevailing ideas derived from the amyloid' or tau' hypotheses. This outstanding publication provides researchers, clinicians, students and other professionals interested in neurodegenerative disorders with a comprehensive update on current trends and future directions in therapy development, with special focus on advances in clinical trial designs.
Alzheimer's disease and dementia—which can begin in the 30s—are on the increase, and may soon overwhelm our health-care systems. Yet individuals can do much to educate themselves and learn how to minimize their risks. A prudent diet, lifestyle modifications, nutritional supplements, exercise and activities to stimulate the brain are some of the best ways to prevent or delay Alzheimer's disease. Use your brain or lose it! That's all easy to say, but how scientific are these admonitions and how do we change our habits, anyway? Vitamins, minerals and food supplements are discussed in relation to memory and other functions, as well as an overview of medications, the effects of wine, and the ...
Presents an overview of the cellular and molecular mechanisms underlying the development of cognitive impairment. This book integrates discoveries concerning dementia, such as mild cognitive impairment and Alzheimer's disease associated dementia, retardation syndromes, and psychiatric and neurological disorders related cognitive impairments.