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This book reviews the important new field of PET/CT-guided biopsy, which is of potential value in optimizing the diagnostic yield of biopsies. The role of this technology is examined in a range of malignancies, including lymphoma, pancreatic, breast cancer and CNS malignancies. True positive and false positive cases are presented and discussed, and many aspects of PET and pathology are addressed. The book describes many case presentations illustrated with mostly 18F-FDG PET/CT images, but also other PET radiopharmaceuticals such as 18F-FLT. The three editors are expert nuclear medicine physicians from Europe and North and South America, and the range of experiences gained in using PET/CT across the globe is reflected in the book.
This book presents up-to-date information on one of the hottest topics in prostate cancer, namely bone metastases. The most recent developments with respect to biology, pathology, diagnosis, and treatment are described, providing readers with an excellent understanding of the mechanisms of metastasis formation, the characteristics of metastases, their aggressiveness, and prognostic factors for treatment response. The coverage includes discussion of all of the best available options (laboratory, radiology, and nuclear medicine) for achieving early diagnosis and both established and novel therapeutic approaches. Detailed information is provided on hormonal manipulations, bone-targeted agents, vaccines, taxanes, and other treatments that are enriching the therapeutic armamentarium. The editors can be considered leaders in the field, with great experience in diagnostic and clinical oncology and research, and the authors are experts in diverse specialties. This ensures a multidisciplinary approach, mirroring the current situation in which treatment in patients with bone metastases is undertaken by a team of specialists and health professionals in a variety of fields.
Nuclear medicine is a medical imaging specialty involving the use of radioactive compounds for diagnostic and therapeutic purposes. As a medical branch, it is considered part of Diagnostic Imaging, but differs substantially from Radiology with respect to the source of the radiation made visible by the diagnostic devices. Nuclear medicine adopts also some types of radioactive emissions for therapeutic purposes, allowing the employment of the metabolic properties of the radiopharmaceuticals for the cure of certain clinical conditions and malignant diseases. Nuclear medicine is a relatively recent discipline and owes its origins to the discovery of natural radioactivity and the development of t...
Nuclear Oncology a contemporary narrative of the role of nuclear medicine in oncology with an emphasis on SPECT/CT and PET/CT with additional comments when appropriate on the potential application of PET/MR and to a lesser degree, targeted radionuclide therapy. This book focuses on the use of radionuclides in the diagnosis and treatment of malignant diseases. It describes relevant approved and investigational clinical applications, instrumentation & technology, chemistry and practical clinical issues in nuclear oncology. The basic science and current research topics of nuclear oncology are addressed in separate chapters. Nuclear medicine has become an essential component to all phases of the...
Dr. Samir Taneja is serving as the Guest Editor for this issue that provides updated and technical content on imaging techniques in urology. Top experts provide clinical reviews on the following topics: Dual-Energy Computed Tomography in Genitourinary Imaging; Diffusion-Weighted Genitourinary Imaging; Upper and Lower Tract Urothelial Imaging Using Computed Tomography Urography; Imaging of Solid Renal Masses; Imaging of Cystic Renal Masses; Image-Guided Renal Interventions; Practical Approach to Adrenal Imaging; Technique of Multi-parametric MRI of the prostate; Multi-parametric MRI- Interpretation Including PIRADS v2; Prostate MRI for Staging; Prostate MRI for Post-Treatment Evaluation and Recurrence; Imaging of Prostate Cancer Using 11C-Choline PET/Computed Tomography; Imaging of Prostate Cancer Using Fluciclovine; and Gallium-68 Prostate-Specific Membrane Antigen PET Imaging. Readers will come away with a clearer understanding of how the latest imaging modalities are utilized for disease diagnosis and management.
This issue provides a complete update on PET imaging of lymphoma, starting with a clinical assessment of lymphoma and the role of medical imaging. The role of structural imaging in lymphoma is then discussed. From a Nuclear Medicine perspective, FDG-PET in lymphoma is reviewed, as is the role of FDG-PET in pediatric lymphoma. Next, the role of non-FDG tracers in lymphoma is reviewed. Other articles cover the role of fMRI and optical imaging in lymphoma, the role of diffusion-weighted MRI in lymphoma, FDG-PET in personalization of therapy in patients with lymphoma, and PET and radiation oncology in lymphoma.
This issue of PET Clinics focuses on Prostate Cancer Imaging and Therapy, and is edited by Drs. Cristina Nanni and Richard P. Baum. Articles will include: Clinicians Need for Imaging of Prostate Cancer; Imaging of Prostate Cancer using 11C-Choline; Imaging of Prostate Cancer using FACBC; Imaging of Prostate Cancer using Ga-Bombesin; Imaging of Prostate Cancer using 18F-Choline; Imaging of Prostate Cancer using Cu-64 Prostate-specific membrane antigen; From bench to bed: New Gastrin releasing peptide receptor-directed radioligands and their use in prostate cancer; Imaging of Prostate Cancer using Ga-68 Prostate-specific membrane antigen; Imaging of Prostate Cancer using F-18 Prostate-specific membrane antigen; Imaging of Prostate Cancer using uPAR-PET; PET/CT for radiation therapy planning of Prostate Cancer; and more!
This book discusses the most significant recent advances in oncological molecular imaging, covering the full spectrum from basic and preclinical research to clinical practice. The content is divided into five sections, the first of which is devoted to standardized and emerging technologies and probe designs for different modalities, such as PET, SPECT, optical and optoacoustic imaging, ultrasound, CT, and MRI. The second section focuses on multiscale preclinical applications ranging from advanced microscopy and mass spectroscopy to whole-body imaging. In the third section, various clinical applications are presented, including image-guided surgery and the radiomic analysis of multiple imaging features. The final two sections are dedicated to the emerging, crucial role that molecular imaging can play in the planning and monitoring of external and internal radiotherapy, and to future challenges and prospects in multimodality imaging. Given its scope, the handbook will benefit all readers who are interested in the revolution in diagnostic and therapeutic oncology that is now being brought about by molecular imaging.