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Neurobiology of Disease is aimed at any basic scientist or clinician scientist teaching a course or conducting research on the basic science underlying the major neurological diseases. It provides an excellent overview of cutting-edge research on the fundamental disorders of the nervous system, including physiological and molecular aspects of dysfunction. The major categories of neurological disease are covered, and the chapters provide specific information about particular diseases exemplifying each of these categories. Sufficient clinical information is included to put into perspective the basic mechanisms discussed. The book assembles a world-class team of section editors and chapters written by acknowledged experts in their respective fields. - Provides cutting edge information about fundamental mechanisms underlying neurological diseases - Amply supplied with tables, illustrations and references - Includes supporting clinical information putting the mechanisms of disease into perspective
The behavioral neuroscience of thirst and sodium appetite are research ventures that have expanded dramatically in recent years. Work done in the mid-1950s and early 1960s made it clear that drinking behavior could be affected by direct manipulations of the brain, especially by brain damage and by pharmacological treat ments. Since that. time experimental approaches have diversified and the research enterprise has attracted the interest of a broad international community of scientists. Many aspects of both thirst and sodium appetite are being studied. The most prominent of these are: 1) phylogenetic and ontogenetic aspects of the phenomena of drink ing behavior, 2) the mechanisms of a variet...
First multi-year cumulation covers six years: 1965-70.
One landmark in the long history of biological studies on the "slime mold" Physarum polycephalum was the introduction of chemi cally defined growth conditions for the plasmodial phase of this organism in the laboratory of Harold P. Rusch in Wisconsin in the 1950s. A number of investigators began working with Physarum in that era, then dispersed over the world. In the 1950s to 1960s, the regular meetings of Physarum workers in North America were commonly held in Wisconsin. Strong new scientific initiatives in Physarum have grown up independently, from the disciplines of genetics, cytology, photo biology, and biophysics, in countries scattered over the world from Japan to Poland, Germany, France, the Netherlands, Norway, Spain, Turkey, and Great Britain. Infusion of the technical power of contemporary molecular biology--in particular, gene cloning and monoclonal antibodies--has brought these dispersed investigators into mutual communication. It was therefore timely and appropriate to assemble the Physarum community again in Wisconsin after a hiatus of 20 years, at a conference in the Friedrick Conference Center at the University of Wisconsin, Madison, from July 8 to 13, 1985.
This book explains how the computer programs work and why and when they can be applied to problems in toxicology. It discusses the statistical models used and their applications in a general fashion. The book overviews the problems that can arise from the blind use of the statistical models.
Reference to the design of new insecticides nontoxic to the environment and the public emphasizing optimal food production with greater safety. Some 30 international experts examine topics including new types of active molecules among natural products and animal toxins; insect metabolic and organ sy
This volume summarises the lecture and poster sessions of a NATO advanced workshop held in Edinburgh, July 15th-19th, 1985. The workshop was held to bring together plant scientists of many different disciplines but who share a common interest in the regulatory role of calcium in plant development. Although this volume covers the formal proceedings, an equal length of time was devoted to discussion both in large and small groups. A little of the flavour of the directions and character of the discussions will be found in the final article by David Clarkson which was written to cover this other wise uncovered area of the workshop. The volume reflects much of the current excitement in the field of plant calcium research. Many of the participants are pioneers in their res pective areas and the extent to which the last five years has seen a drama tic unfolding, a complete inversion of the role of calcium from simple macro nutrient to major metabolic and developmental controller is recounted here. The material is new and much of it unpublished. In plant physiology, the eighties may yet be designated the decade of calcium.