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Fungal Infections, An Issue of Infectious Disease Clinics of North America
There have been major advances in new therapies, diagnostic tools, and strategies for treatment and prevention of fungal infections. Despite these encouraging developments, large numbers of patients are at risk for infectious diseases, and the epidemiology of invasive mycoses continues to emerge. The diagnosis of these infections remains difficult, and treatment outcomes in highly immunosuppressed patients remain poor. Thus, this issue is devoted to state-of-the-art updates on fungal infections by internationally recognized authorities in this field. Some topics covered are Antifungal agents; State-of-the-art culture, identification, and resistance testing of fungal pathogens; Non-culture diagnostics in fungal disease; Contemporary strategies in the prevention and management of fungal infections; Invasive candidiasis; Invasive aspergillosis; Mucormycoses; and Cryptococcosis to name a few.
Fungal Infections, An Issue of Infectious Disease Clinics of North America, E-Book
Fungal Infections, An Issue of Infectious Disease Clinics of North America, E-Book
Candida and Candidiasis
The underlying mechanisms of Candida and candidiasis and promising new directions in drug discovery and treatment. • Reviews all aspects of this common fungal pathogen and its impact on human health, from the basic biology of Candida albicans to the clinical management of candidiasis. • Reviews the latest basic and clinical research, focusing on findings in genome variability, host-pathogen interactions, antifungal resistance and drug discovery, and diagnostics to foster better understanding and treatment of candidiasis. • Examines recent discoveries that have shed light on morphogenesis and the cell cycle, including how new findings on host responses may have applications for the diagnosis of blood-borne candidiasis.
Meningitis and Encephalitis
Meningitis and Encephalitis are associated with high rates of mortality and neurological sequelae. The differential diagnosis includes a wide spectrum of infectious and non-infectious etiologies, some requiring urgent therapy for survival. The current management challenges in patients with meningitis and encephalitis include a low sensitivity of meningeal signs, overutilization of unnecessary screening cranial imaging, delays in diagnosis of urgent treatable causes, a large proportion of unknown etiologies, low sensitivity of current microbiological techniques especially in the setting of previous antibiotic therapy, underutilization of available molecular diagnostic tests, and empiric antib...
Infectious Diseases in Solid-Organ Transplant Recipients
This book describes a practical approach to the diagnosis, management, and prevention of infectious complications in solid-organ transplant (SOT) candidates and recipients, based on both up-to-date clinical evidence and state of the art expert opinion from world-renowned experts in the field. The book is divided into three parts, the first of which explains risk assessment and the general approach to infectious diseases in the pre-, peri-, and early and late post-transplant periods. The remaining two sections address the prevention and treatment of infection with particular pathogens and the management of specific syndromes, such as pneumonia, CNS infections, UTIs, and skin infections. Infec...
Hospital Epidemiology and Infection Control
Thoroughly revised and updated for its Fourth Edition, this highly acclaimed volume is the most comprehensive reference on hospital epidemiology and infection control. Written by over 150 leading experts, this new edition examines every type of hospital-acquired (nosocomial) infection and addresses every issue relating to surveillance, prevention, and control of these infections in patients and in healthcare workers. This new edition features new or significantly increased coverage of emerging infectious diseases, avian influenza, governmental regulation of infection control and payment practices related to hospital-acquired infections, molecular epidemiology, the increasing prevalence of community-acquired MRSA in healthcare facilities, system-wide infection control provisions for healthcare systems, hospital infection control issues following natural disasters, and antimicrobial stewardship in reducing the development of antimicrobial-resistant organisms.
Diagnosis and Treatment of Fungal Infections
Diagnosis and Treatment of Fungal Infections, 3rd Edition contains the latest research and clinical evidence on fungal infections in humans. Updated again by globally recognized experts, this concise text is divided into sections dedicated to the patient approach, laboratory and radiological diagnosis, systemic antifungal agents, mycoses, and instructive cases. It is a concise but comprehensive resource for use in conjunction with patient care duties and in teaching. It is the perfect guide for hospital-based primary care physicians, oncologists, critical care specialists, and infectious disease fellows with limited training or experience in the identification and management of fungal infections.
Managing Infections in Patients With Hematological Malignancies
Managing infections that complicate care of neutropenic patients with leukemia and hematopoietic stem cell recipients has become a distinct specialty. In Managing Infections in Patients with Hematological Malignancies, the authors and editor draw on their extensive expertise while providing a roadmap for hematologists to efficiently manage the complex infections within their patients. The first section of the text reviews viral, bacterial, and fungal pathogens, and provides brief descriptions of the microbes and diseases they cause in patients with hematological malignancies. The second section is devoted to management of infections in patients with the different underlying hematological malignancies, while the third addresses several important topics that are often ignored in most books about infections and hematological malignancies. Managing Infections in Hematological Malignancies is a useful tool for all clinicians and practicing hematologists who treat individual patients and aspire to build stronger infectious diseases programs within their respective cancer centers.
Complex Infectious Disease Issues in the Intensive Care Unit, An Issue of Infectious Disease Clinics of North America
The Guest Editors, coming from the Critical Care Medicine Department in the NIH, are the top thought leaders in the area of infections in critical care. Their topic selections in this issue reflect the most clinically relevant and current information. The issue specifically covers the following topics: Catheter-related bloodstream infections: special considerations in diagnosis in the ICU; Sepsis-How does the new definition help clinicians; Therapeutic drug monitoring of antibiotics; High containment pathogen preparation; Multidrug resistant gram negative infections and enterococcus; Strategies to prevent transmission of resistant organisms; Antibiotic Stewardship: What the intensivist should know; C. Difficile infection in the ICU; Immunocompromised critically ill; Rapid diagnostics: The use of procalcitonin; Respiratory viruses in the ICU: Significance of rhino/rsv updates/adenovirus metapneumovirus; Management of invasive fungal disease in the ICU; Inhaled/Nebulized antibiotics. Infectious disease physicians and intensivists will be armed with the information they need to diagnose and treat patients with infections in the ICU.
