Welcome to our book review site go-pdf.online!
You may have to Search all our reviewed books and magazines, click the sign up button below to create a free account.
Receptor Dynamics in Neural Development
This book provides a comprehensive review of what receptors do in the nervous system, how they do it, the mechanisms by which receptor function is regulated, and the consequences of normal and abnormal receptor function. It contains a series of interrelated chapters describing key neurotransmitter receptors, protein kinases, and protein phosphatases, and details their expression and composition in the development of the central nervous system (CNS).
Glutamate
The volume presents a comprehensive and up-to-date treatise of the glutamatergic synapse and its environment. Particular emphasis is on the localizations of the molecular constituents of the synaptic machinery. Immunogold and other high-resolution methods are used extensively. Each chapter presents new data that have not previously been reviewed. The material presented forms the basis for work directed to understanding the functional properties of excitatory synapses in greater depth, to discover mechanisms of neurological and psychiatric disorders and novel methods for treatment. Chapter 1 deals with the transmitter molecule itself, mechanisms of release and pathways for glutamate synthesis...
Molecular Biology and Brain Ischemia
The latest advances in molecular neurobiology have contributed significantly to understanding the pathophysiology of brain ischemia/hypoxia and have led to more effective measures to protect against ischemic brain damage. An especially important feature of this book is the new insight it provides into the molecular neurobiology of neurotransmission, the functional structures of glutaminergic receptors, the functional proteins of synapses, and synaptic plasticity. Recent progress is reported in elucidating the pathophysiological roles of NO, free radicals, and intracellular pH and calcium ions in brain ischemia/hypoxia, and a unique approach for protective and therapeutic measures against this condition is described. Molecular Neurobiology and Brain Ischemia will be of special interest to researchers and practitioners in neurobiology and related fields, including neurosurgeons.
Ionotropic Glutamate Receptors in the CNS
With contributions by numerous experts
Cortical Development
This book reviews recent progress in cortical development research, focusing on the mechanisms of neural stem cell regulation, neuronal diversity and connectivity formation, and neocortical organization. Development of the cerebral cortex, the center for higher brain functions such as cognition, memory, and decision making, is one of the major targets of current research. The cerebral cortex is divided into many areas, including motor, sensory, and visual cortices, each of which consists of six layers containing a variety of neurons with different activities and connections. As this book explains, such diversity in neuronal types and connections is generated at various levels. First, neural stem cells change their competency over time, giving sequential rise to distinct types of neurons and glial cells: initially deep layer neurons, then superficial layer neurons, and lastly astrocytes. The activities and connections of neurons are further modulated via interactions with other brain regions, such as the thalamocortical circuit, and via input from the environment. This book on cortical development is essential reading for students, postdocs, and neurobiologists.
Progress in Drug Research
S. Ren and E.J. Lien: CaCo-2 cell permeability vs human gastrointestinal absorption: QSPR analysis.- J.C.G. Halford and J.E. Blundell: Pharmacology of appetite suppression.- B. Olivier, W. Soudijn and I. van Wijngaarden: Serotonin, dopamine and norepinephrine transporters in the central nervous system and their inhibitors.- D. Poyner, H. Cox, M. Bushfield, J.M. Treherne and M.K. Demetrikopoulos: Neuropeptides in drug research.- M. Kumari and M.K. Ticku: Regulation of NMDA receptors by ethanol.- H. Horikoshi, T. Hashimoto and T. Fujiwara: Troglitazone and emerging glitazones: new avenues for potential therapeutic benefits beyond glycemic control.- Rosamund C. Smith and Simon J. Rhodes: Applications of developmental biology to medicine and animal agriculture.
The olivo-cerebellar system
During the last decades, investigations on the olivo-cerebellar system have attained a high level of sophistication, which led to redefinitions of several structural and functional properties of neurons, synapses, connections and circuits. Research has expanded and deepened in so many directions and so many theories and models have been proposed that an ensemble review of the matter is now needed. Yet, hot topics remain open and scientific discussion is very lively at several fronts. One major question, here as well as in other major brain circuits, is how single neurons and synaptic properties emerge at the network level and contribute to behavioural regulation via neuronal plasticity. Othe...
Physiology Or Medicine, 1991-1995
During the period 1991 ? 1995, important areas of physiological/medical research being recognized were ion channels in cells, protein phosphorylation, split genes, G-proteins and genetic control of embryonic development. The following is a list of the Nobel laureates for those years, with a description of the works that won them their prizes: (1991) E NEHER & B SAKMANN ? for their discoveries concerning the function of single ion channels in cells; (1992) E H FISCHER & E G KREBS ? for their discoveries concerning reversible protein phosphorylation as a biological regulatory mechanism; (1993) R J ROBERTS & P A SHARP ? for their discoveries of split genes; (1994) A G GILMAN & M RODBELL ? for their discovery of G-proteins and the role of these proteins in signal transduction in cells; (1995) E B LEWIS, C NSSLEIN-VOLHARD & E F WIESCHAUS ? for their discoveries concerning the genetic control of early embryonic development.
The NMDA Receptors
This volume provides a history of and an update on the functional status of the NMDA receptors. The NMDA receptors are essential for neuronal development, synaptic plasticity, learning, and cell survival. It covers molecular, cellular, anatomical, biochemical, and behavioral aspects, to highlight their distinctive regulatory properties, their functional significance, and their therapeutic potential in a number of diseases. A group of international experts discuss the development of NMDA receptors, their basic functions, and how they are implicated in a wide range of diseases including depression, psychosis, and pain.
