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This book describes Carmeli's cosmological general and special relativity theory, along with Einstein's general and special relativity. These theories are discussed in the context of Moshe Carmeli's original research, in which velocity is introduced as an additional independent dimension. Four- and five-dimensional spaces are considered, and the five-dimensional braneworld theory is presented. The Tully-Fisher law is obtained directly from the theory, and thus it is found that there is no necessity to assume the existence of dark matter in the halo of galaxies, nor in galaxy clusters.The book gives the derivation of the Lorentz transformation, which is used in both Einstein's special relativ...
This book addresses the recent trends and clinical research being reported in last 5 to 10 years in the field of nasal drug delivery systems. In recent years, interest in using nasal passage as drug absorption site has received increased attention from formulation scientists. Nasal passages, even though a small surface area of the body as compared to other absorption passage such as Gastrointestinal tract or skin, show significant possibility for drug absorption at a quicker rate. There is also a possibility of delivering drugs to the brain using this passage and targeting drugs through the nasal passage. The book has 19 chapters addressing various aspects of nasal drug delivery systems such...
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
The text covers a wide range of topics such as mathematical modeling of crop pest control management, water resources management, impact of anthropogenic activities on atmospheric carbon dioxide concentrations, impact of climate changes on melting of glaciers and polar bear populations, dynamics of slow–fast predator-prey system and spread and control of HIV epidemic. It emphasizes the use of mathematical modeling to investigate the fluid flow problems including the breaking of viscoelastic jet, instability arising in nanofiber, flow in an annulus channel, and thermal instability in nano-fluids in a comprehensive manner. This book will be a readily accessible source of information for the ...
Focused on central nervous system (CNS) drug discovery efforts, this book educates drug researchers about the blood-brain barrier (BBB) so they can affect important improvements in one of the most significant – and most challenging – areas of drug discovery. • Written by world experts to provide practical solutions to increase brain penetration or minimize CNS side-effects • Reviews state-of-the-art in silico, in vitro, and in vivo tools to assess brain penetration and advanced CNS drug delivery strategies • Covers BBB physiology, medicinal chemistry design principles, free drug hypothesis for the BBB, and transport mechanisms including passive diffusion, uptake/efflux transporters, and receptor-mediated processes • Highlights the advances in modelling BBB pharmacokinetics and dynamics relationships (PK/PD) and physiologically-based pharmacokinetics (PBPK) • Discusses case studies of successful CNS and non-CNS drugs, lessons learned and paths to the market
With the rapid advancements in polymer research, polymers are finding newer applications such as scaffolds for tissue engineering, wound healing, flexible displays, and energy devices. In the same spirit, this book covers the key features of recent advancements in polymeric materials and their specialty applications. Divided into two sections – Polymeric Biomaterials and Polymers from Sustainable Resources, and Polymers for Energy and Specialty Applications – this book covers biopolymers, polymer-based biomaterials, polymer-based nanohybrids, polymer nanocomposites, polymer-supported regenerative medicines, and advanced polymer device fabrication techniques. FEATURES Provides a comprehen...