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Compiles current tested and proven approaches to synthesize novel nucleoside analogues Featuring contributions from leading synthetic chemists from around the world, this book brings together and describes tested and proven approaches for the chemical synthesis of common families of nucleoside analogues. Readers will learn to create new nucleoside analogues with desired therapeutic properties by using a variety of methods to chemically modify natural nucleosides, including: Changes to the heterocyclic base Modification of substituents at the sugar ring Replacement of the furanose ring by a different carbo- or heterocyclic ring Introduction of conformational restrictions Synthesis of enantiom...
The authoritative guide for dietetic students and both new and experienced dietitians – endorsed by the British Dietetic Association Now in its sixth edition, the bestselling Manual of Dietetic Practice has been thoroughly revised and updated to include the most recent developments and research on the topic. Published on behalf of the British Dietetic Association, this comprehensive resource covers the entire dietetics curriculum, and is an ideal reference text for healthcare professionals to develop their expertise and specialist skills in the realm of dietetic practice. This important guide includes: The latest developments and scientific evidence in the field New data on nutrition and h...
Despite their variety, the vibration phenomena from many different engineering fields can be classified into a relatively few basic excitation mechanisms. The classification enables engineers to identify all possible sources of excitation in a given system and to assess potential dangers. This graduate-level text presents a synthesis of research results and practical experience from disparate fields in the form of engineering guidelines. It is particularly geared toward assessing the possible sources of excitation in a flow system, in identifying the actual danger spots, and in finding appropriate remedial measures or cures. Flow-induced vibrations are presented in terms of their basic eleme...
Orofacial pain - defined as pain lasting over three months in the mouth or face - is increasing in prevelance, with approximately 7% of the UK population having experienced it. It is currently managed by either dentists or general medical practitioners, both of whom have radically different approaches to treatment. While management of orofacial pain has improved quite dramatically over recent years, it is essential that dentists and general practitioners are aware of these advances and of the differences in their approaches. This concise handbook takes an evidence-based psychosocial approach to the management of patients with pain in the face or mouth and provides basic guidelines to facilitate care quickly in the clinical setting. The book will serve as a useful guide for dental practitioners, specialists in orofacial pain, trainee pain specialists, neurologists with an interest in pain, specialist pain nurses, as well as general medical practitioners.
This text re-evaluates our understanding of salivary gland disease. It attempts to integrate the newer clinical findings with the historical pathological record and to highlight, and where possible resolve, any conflicts between the two.
This book bridges the gap between the theoretical work of the rheologist, and the practical needs of those who have to design and operate the systems in which these materials are handled or processed. It is an established and important reference for senior level mechanical engineers, chemical and process engineers, as well as any engineer or scientist who needs to study or work with these fluids, including pharmaceutical engineers, mineral processing engineers, medical researchers, water and civil engineers. This new edition covers a considerably broader range of topics than its predecessor, including computational fluid dynamics modelling techniques, liquid/solid flows and applications to a...
Basic fluid dynamic theory and applications in a single, authoritative reference The growing capabilities of computational fluid dynamics and the development of laser velocimeters and other new instrumentation have made a thorough understanding of classic fluid theory and laws more critical today than ever before. Fundamentals of Fluid Mechanics is a vital repository of essential information on this crucial subject. It brings together the contributions of recognized experts from around the world to cover all of the concepts of classical fluid mechanics-from the basic properties of liquids through thermodynamics, flow theory, and gas dynamics. With answers for the practicing engineer and real-world insights for the student, it includes applications from the mechanical, civil, aerospace, chemical, and other fields. Whether used as a refresher or for first-time learning, Fundamentals of Fluid Mechanics is an important new asset for engineers and students in many different disciplines.
This volume comprises the communications presented at the ETC 11, the EUROMECH European Turbulence conference held in 2007 in Porto. The scientific committee has chosen the contributions out of the following topics: Acoustics of turbulent flows; Atmospheric turbulence; Control of turbulent flows; Geophysical and astrophysical turbulence; Instability and transition; Intermittency and scaling; Large eddy simulation and related techniques; MHD turbulence; Reacting and compressible turbulence; Transport and mixing; Turbulence in multiphase and non-Newtonian flows; Vortex dynamics and structure formation; Wall bounded flows.
This volume comprises a selection of the best papers presented at the Seventh Interna tional Symposium on Applications of Laser Techniques to Fluid Mechanics held at The Calouste Gulbenkian Foundation in Lisbon, during the period of July 11 to 14,1994. The papers describe Applications to Fluid Mechanics, Applications to Combustion, Instrumentation for Velocity and Size Measurements and Instrumentation for Whole Field Velocity and demonstrate the continuing and healthy interest in the development of understanding of the methodology and implementation in terms of new instru mentation. The prime objective of this Seventh Symposium was to provide a forum for the presen tation of the most advance...