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Acute Megakaryoblastic Leukaemia Shows High Frequency of Chromosome 1q Aberrations and Dismal Outcome
Abstract: Acute megakaryoblastic leukaemia (AMKL) is associated with poor prognosis. Limited information is available on its cytogenetics, molecular genetics and clinical outcome. We performed genetic analyses, evaluated prognostic factors and the value of allogeneic haematopoietic stem cell transplantation (allo-HSCT) in a homogenous adult AMKL patient cohort. We retrospectively analysed 38 adult patients with AMKL (median age: 58 years, range: 21-80). Most received intensive treatment in AML Cooperative Group (AMLCG) trials between 2001 and 2016. Cytogenetic data showed an accumulation of adverse risk markers according to ELN 2017 and an unexpected high frequency of structural aberrations ...
Management of Hematologic Malignancies
Hematologic malignancies were the first human cancers to be studied in depth at the molecular level, and recent years have seen important advances in treatment. This comprehensive reference book covers the full range of hematologic malignancies, including all subtypes of leukemias, lymphomas, and plasma cell dyscrasias. Authored by internationally known experts, each chapter emphasizes diagnostic work-up, staging, and therapeutic approaches. Up-to-date hematopathology, treatment, and outcomes data are presented in a way which is directly applicable to patient care. Highly illustrated with color images, graphs, flowcharts and treatment algorithms, the book is perfect for quick clinical reference as well as providing detailed reference lists for further study. With its authoritative and practical focus and visually stimulating presentation, this is a key text for hematology and oncology fellows, physicians, oncology nurses, physician assistants and other healthcare workers in the field of oncology.
British Poetry Magazines, 1914-2000
Records the world of the Little Magazine: A world where famous authors are first found as unknowns. This title includes entries, which give details of the editors involved, publication date and other information, including lists of libraries where each can be found.
Contemporary Human Resource Management
Providing critical and pragmatic coverage of contemporary ideas in human resource management, this text looks at some of the key issues and topics in the field.
Gifts
BpNichol's The Martyrology is a long poem begun in 1967 and continuing until Nichol's death in 1988. It includes Books 1 & 2 (1972), Book(s) 7 & (1990), and Ad Sanctos: Book 9 (1992). The text in this volume is a facsimile, with minor corrections, of the 1990 edition of Gifts. --Coach House Books.
Diagnostic Imaging of Exotic Pets
Jetzt auch in englischer Sprache! Dieser Atlas ist eine bislang einmalige Zusammenstellung aller bildgebenden Verfahren für die drei großen „Heimtierklassen" Vögel, Kleinsäuger und Reptilien. Separate Sektionen des Buches behandeln die drei Tierklassen, was ein schnelles und spezifisches Nachschlagen von Informationen und Bildreferenzen ermöglicht. Jede Sektion beginnt mit der anatomischen Darstellung der Körperregionen in den einzelnen Diagnostikverfahren. In einem zweiten Teil werden die häufigsten pathologischen Befunde nach den Organsystemen dargestellt und im Vergleich besprochen. Die vergleichende Darstellung ermöglicht die schnelle und richtige Diagnose mit dem adäquaten Diagnostikverfahren. Alle Röntgen-, Ultraschall-, CT- und MRT-Bilder sind eindeutig beschriftet. Mit rund 1500 Abbildungen ist dieser Atlas ein konkurrenzloses diagnostisches Archiv für die Heimtierpraxis.
The Diamond Noodle
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The Governor's Dilemma
The Governor's Dilemma develops a general theory of indirect governance based on the tradeoff between governor control and intermediary competence; the empirical chapters apply that theory to a diverse range of cases encompassing both international relations and comparative politics. The theoretical framework paper starts from the observation that virtually all governance is indirect, carried out through intermediaries. But governors in indirect governance relationships face a dilemma: competent intermediaries gain power from the competencies they contribute, making them difficult to control, while efforts to control intermediary behavor limit important intermediary competencies, including e...
Public Accounts
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Toxoplasma Gondii
This 2e of Toxoplasma gondii reflects the significant advances in the field in the last 5 years, including new information on the genomics, epigenomics and proteomics of T. gondii as well as a new understanding of the population biology and genetic diversity of this organism. T. gondii remains the best model system for studying the entire Apicomplexa group of protozoans, which includes Malaria, making this new edition essential for a broad group of researchers and scientists. Toxoplasmosis is caused by a one-celled protozoan parasite known as T. gondii. The infection produces a wide range of clinical syndromes in humans, land and sea mammals, and various bird species. Most humans contract to...
