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Neuro-inflammation in Neuronal Death and Repair
Neuroinflammation has been implicated recently in the pathogenesis of many neurodegenerative diseases. The cross-talk between neurons and non-neuronal cells seems to be a critical step in the progression of neurodegeneration and molecules that have a beneficial role may turn into harmful players. Thus, matrix metalloproteinases (MMPs), which are involved in axonal growth and regeneration as well as synaptic plasticity, may also have detrimental effects. Recent evidence has linked MMPs to conditions like ischemia, multiple sclerosis, Alzheimer's disease and suggested that, together with their role in the degradation of extracellular macromolecules, MMPs could work as important signalling mole...
Handbook on Migration and Security
This Handbook provides a state-of-the-art analysis of the critically important links between migration and security in a globalising world, and presents original contributions suggesting innovative and emerging frontiers in the study of the securitization of migration. Experts from different fields reflect on their respective conceptualisations of the migration-security nexus, and consider how an interdisciplinary and multifaceted dialogue can stimulate and enrich our understanding of the securitisation of migration in the contemporary world.
Extraterritorial Immigration Control
This work analyses the legal challenges posed by contemporary practices of extraterritorial immigration control: visas, pre-embarkation checks and the interception of irregular migrants. It examines the international law framework, and provides case-studies from Europe, Australia and the United States.
Meaning Making in International Criminal Law
This book explores the normative dimensions of the acts that constitute international crimes. The book conceptualises the normative dimensions of these acts as processes of construction and meaning making. Developing a novel methodological approach, it identifies the narratives and discourses that emerge in practice as central for understanding the normative meanings of these acts. Using the crimes of attacks on cultural property, pillage, sexual violence and reproductive violence as case studies, the book offers a historical, conceptual, and discursive analysis of these crimes to develop a dynamic, pluralist and socially constructed account of wrong in international criminal law.
Domesticating International Criminal Law
This book provides an essential and critical overview of the most significant issues concerning the domestication of international criminal law, in particular with regard to the implementation of the ICC Statute. It discusses the most recent proposals for reform of the German Code of Crimes under International Law, the "Völkerstrafgesetzbuch", 20 years after its entering into force and introduces the project for an Italian code of international crimes drafted by the Committee of experts established in 2022 by the Ministry of Justice. Following the adoption of the ICC Statute, many States, including Germany with the "Völkerstrafgesetzbuch", introduced specific legislation to incorporate int...
Defining the Limits of Outer Space for Regulatory Purposes
With different countries ascribing to different theories of air space and outer space law, Dr. Bittencourt Neto proposes in this Brief a reassessment of the international law related to the extension of state territories vertically. Taking into consideration the vast number of proposals offered by scholars and diplomatic delegations on this subject matter, as well as the principles of comparative law, a compromise to allow for peaceful development is the only way forward. The author argues for setting the delimitation of the frontier between air space and outer space at 100 km above mean sea level through an international treaty. This would also regulate passage rights for space objects duri...
The Barbarians of Ancient Europe
Deals with the reality of the indigenous peoples of Europe - Thracians, Scythians, Celts, Germans, Etruscans, and other peoples of Italy, the Alps, and beyond.
Comparative Visions in Space Law
Dopo decenni di grande sviluppo del settore digitale, assistiamo a una rinnovata attenzione per lo spazio di soggetti pubblici e privati, con la simultanea presenza di interessi nazionali strategici di difesa e geopolitici e interessi commerciali rivolti al profitto. Il diritto dello spazio si caratterizza per un nocciolo internazionalistico, ma, oggi, non può più essere semplicemente definito come una branca del diritto internazionale. Vi sono problemi e complicazioni dovuti alla presenza di interessi differenti e di culture giuridiche differenti che richiedono uno sforzo significativo di compromesso e apertura mentale per essere riconciliati con comune soddisfazione, per ottenere la coop...
Individual Criminal Responsibility for Autonomous Weapons Systems in International Criminal Law
In this book Barry de Vries addresses the issue of autonomous weapons in international criminal law. The development of autonomous weapon systems is progressing. While the technology advances, attempts to regulate these weapons are not keeping pace. It is therefore likely that these weapons will be developed before a new legal framework is established. Many legal questions still remain and one of the most important ones among them is how individual responsibility will be approached. Barry de Vries therefore considers this issue from a doctrinal international criminal law perspective to determine how the current international criminal law framework will address this topic.
New Insights to Neuroimmune Biology
New Insights to Neuroimmune Biology investigates the mechanisms that and functions of the Neuroimmune Regulatory Supersystem. Covering molecular regulation of cytokines in brain astrocytes, immunoregulation by the sympathetic nervous system, circadian regulation of immune reactions, antigen recognition by the CNS, the modulation of the immune response by head injury, neurogenic inflammation, the role of tachykinins in asthma and allergic disease, defence and defeat reactions, cytokines, behavior and affective disorders, increased activity of type 1 helper T cell functions after reward stimulation.This book has relevance to the entire scientific community in Biology, Medicine and Veterinary medicine as it discusses molecular, cellular, organic and systemic aspects as well as the physological, pathophysiological and behavioral mechnisms which are involved in Neuroimmiune Biology.
