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Severe asthma is a form of asthma that responds poorly to currently available medication, and its patients represent those with greatest unmet needs. In the last 10 years, substantial progress has been made in terms of understanding some of the mechanisms that drive severe asthma; there have also been concomitant advances in the recognition of specific molecular phenotypes. This ERS Monograph covers all aspects of severe asthma – epidemiology, diagnosis, mechanisms, treatment and management – but has a particular focus on recent understanding of mechanistic heterogeneity based on an analytic approach using various ‘omics platforms applied to clinically well-defined asthma cohorts. How these advances have led to improved management targets is also emphasised. This book brings together the clinical and scientific expertise of those from around the world who are collaborating to solve the problem of severe asthma.
This atlas, in which a wealth of illustrations are supported by clear explanatory text, offers an up-to-date and comprehensive overview of the immediate restoration of teeth and immediate functional loading when using different implant systems and surfaces in patients with single tooth loss or partial or complete edentulism. It provides guidance on all aspects of technique, including procedures for impression and measurement taking, and describes the surgical and prosthetic protocols applicable in various settings. The coverage encompasses the more advanced techniques used for immediate loading of implants placed in conjunction with grafting/augmentation procedures or in fresh extraction sockets, as well as immediate implant loading for mandibular and maxillary full-arch rehabilitation. This atlas will help dental students and practitioners to gain a sound understanding of immediate loading techniques, including their indications and limitations, and to apply them optimally in their practice. The atlas also shows and explains how to integrate a full digital workflow from the intraoral scanner to solve complex cases in a simple way.
An authoritative work that provides a detailed review of the current status of cancer prevention and control practice and research. This volume is an essential reference guide and tool for primary care physicians, the research community and students. Written as a collaborative work by the faculty of the nationally renowned Cancer Prevention and Control Program at the Arizona Cancer Center, this book brings together the expertise of specialists in the field of cancer prevention and control to provide the medical and research community that does not specialize in this field with insight to the disciplines of cancer prevention and control.
This book presents the most current trends in the field of finance and accounting from an international perspective. Featuring contributions presented at the 17th Annual Conference on Finance and Accounting at the University of Economics in Prague, this title provides a mix of research methods used to uncover the hidden consequences of accounting convergence in the private (IFRS) and public sectors (IPSAS). Topics covered include international taxation (from both the micro- and macroeconomic level), international investment, monetary economics, risk management, management accounting, auditing, investment capital, corporate finance and banking, among others. The global business environment sh...
This ground-breaking textbook is the first to cover the new and rapidly developing field of occupational health psychology. Provides a thorough introduction to occupational health psychology and an accessible overview of the key themes in research and practice Each chapter relates to an aspect of the core education curriculum delineated by the European Academy of Occupational Health Psychology Written by internationally recognized experts in the field Examines a host of contemporary workplace health issues, including work-related stress; the psychosocial work environment; positive psychology and employee well-being; psychosocial risk management; workspace design; organizational research methods; and corporate culture and health
The Second Edition of Asthma and COPD: Basic Mechanisms and Clinical Management continues to provide a unique and authoritative comparison of asthma and COPD. Written and edited by the world's leading experts, it continues to be a comprehensive review of the most recent understanding of the basic mechanisms of both conditions, specifically comparing their etiology, pathogenesis, and treatments. * Each chapter considers Asthma and COPD in side-by-side contrast and comparison – not in isolation - in the context of mechanism, triggers, assessments, therapies, and clinical management * Presents the latest and most comprehensive understandings of the mechanisms of inflammation in both Asthma and COPD * Most extensive reference to primary literature on both Asthma and COPD in one source. * Easy-to-read summaries of the latest advances alongside clear illustrations
Pentcheva demonstrates that a fundamental shift in the Byzantine cult from relics to icons, took place during the late tenth century. Centered upon fundamental questions of art, religion, and politics, Icons and Power makes a vital contribution to the entire field of medieval studies.
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