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Modeling Methods for Medical Systems Biology
This book contributes to better understand how lifestyle modulations can effectively halt the emergence and progression of human diseases. The book will allow the reader to gain a better understanding of the mechanisms by which the environment interferes with the bio-molecular regulatory processes underlying the emergence and progression of complex diseases, such as cancer. Focusing on key and early cellular bio-molecular events giving rise to the emergence of degenerative chronic disease, it builds on previous experience on the development of multi-cellular organisms, to propose a mathematical and computer based framework that allows the reader to analyze the complex interplay between bio-molecular processes and the (micro)-environment from an integrative, mechanistic, quantitative and dynamical perspective. Taking the wealth of empirical evidence that exists it will show how to build and analyze models of core regulatory networks involved in the emergence and progression of chronic degenerative diseases, using a bottom-up approach.
Modeling Methods for Medical Systems Biology
This book contributes to better understand how lifestyle modulations can effectively halt the emergence and progression of human diseases. The book will allow the reader to gain a better understanding of the mechanisms by which the environment interferes with the bio-molecular regulatory processes underlying the emergence and progression of complex diseases, such as cancer. Focusing on key and early cellular bio-molecular events giving rise to the emergence of degenerative chronic disease, it builds on previous experience on the development of multi-cellular organisms, to propose a mathematical and computer based framework that allows the reader to analyze the complex interplay between bio-molecular processes and the (micro)-environment from an integrative, mechanistic, quantitative and dynamical perspective. Taking the wealth of empirical evidence that exists it will show how to build and analyze models of core regulatory networks involved in the emergence and progression of chronic degenerative diseases, using a bottom-up approach.
The Massacre at El Mozote
In December 1981 soldiers of the Salvadoran Army's select, American-trained Atlacatl Battalion entered the village of El Mozote, where they murdered hundreds of men, women, and children, often by decapitation. Although reports of the massacre -- and photographs of its victims -- appeared in the United States, the Reagan administration quickly dismissed them as propaganda. In the end, El Mozote was forgotten. The war in El Salvador continued, with American funding. When Mark Danner's reconstruction of these events first appeared in The New Yorker, it sent shock waves through the news media and the American foreign-policy establishment. Now Danner has expanded his report into a brilliant book, adding new material as well as the actual sources. He has produced a masterpiece of scrupulous investigative journalism that is also a testament to the forgotten victims of a neglected theater of the cold war.
Campus de la Diagonal
Aquest llibre presenta una reflexió acadèmica i professional al Campus de la Diagonal amb un ampli ventall d’idees urbanístiques que permeten establir un nou escenari universitari i millorar la relació amb la ciutat..Durant els anys seixanta i setanta del segle passat es varen realitzar diversos projectes d’edificis i recintes universitaris de gran interès (de Carlo, Candilis, Sert). També es varen publicar notables estudis sobre la relació entre la ciutat i la universitat..Feia, però, força anys que aquestes qüestions no semblaven ocupar l’agenda d’arquitectes, urbanistes i responsables universitaris. Per això sembla tan oportú l’esforç de recollir en aquestes poc més de dues-centes planes tot un seguit de riques reflexions i de projectes, tant aquells que responen a encàrrecs concrets de la UB i de la UPC, com aquells que han realitzat un conjunt d’estudiants per recosir i fer ciutat d’una munió d’edificis, sovint de caràcter abstret i poc permeable, tallats per una avinguda de grans dimensions i disposats sense cap visió de conjunt.
Physics Of Emergence And Organization
This book is a state-of-the-art review on the Physics of Emergence. The challenge of complexity is to focus on the description levels of the observer in context-dependent situations. Emergence is not only an heuristic approach to complexity, but it also urges us to face a much deeper question — what do we think is fundamental in the physical world?This volume provides significant and pioneering contributions based on rigorous physical and mathematical approaches — with particular reference to the syntax of Quantum Physics and Quantum Field Theory — dealing with the bridge-laws and their limitations between Physics and Biology, without failing to discuss the involved epistemological features.Physics of Emergence and Organization is an interdisciplinary source of reference for students and experts whose interests cross over to complexity issues.
Rammed Earth Conservation
Includes a free CD containing the full contents of the book. The rammed earth technique, in all its variants, is widespread all over the world. This enormously prevalent building technique harbours an important richness of varieties both in application and in materials used. Interventions on historical rammed earth buildings have also been carried out in all the geographical areas where these structures are found. This historical heritage has undergone diverse forms of reconstruction, conservation, repair, substitution and/or structural consolidation. The different criteria applied require different techniques, materials or forms of intervention. The results of the interventions have also been manifold, both in terms of the impact on the building and the technical and material durability. With a view to these issues, this book deals with rammed earth architecture and its restoration, and, in a more general sense, with the construction techniques and restoration of all earthen structures. Rammed Earth Conservation will be a valuable source of information for academics and professionals in the fields of Civil Engineering, Construction and Building Engineering and Architecture.
