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Approximately 3000 middle and late Cenozoic nearshore marine molluscan taxa from western California are assigned to six time periods, spanning ~25 m.y. In this interdisciplinary study, western California is palinspastically restored for each of the time periods by backsliding and back-rotating large fault blocks or crustal units. Marine fossil assemblages are assigned to nearshore paleoclimatic regions or water masses within palinspastically restored California. In addition, this volume reveals positive feedback mechanisms between paleolatitudinal changes in sea-surface paleotemperature gradients and changes in the diversity of marine mollusks along the California coast through time; defines "equable" based effective temperatures; and analyzes extinction rates among macroinvertebrate marine taxa from coastal California and the possible causes of these extinctions. The late Paleogene to Neogene faunas reflect an increase in faunal diversity related to strengthened temperature gradients, greater extremes in sea-surface temperatures, reduction in temperateness, and the development of an embayed California coastline.
The Upper Paleolithic fossils of the Mladec caves, South Moravia, excavated at the end of the 19th century, hold a key position in the current discussion on modern human emergence within Europe and the fate of the Neanderthals. Although undoubtedly early modern humans - recently radio carbon dated to 31.000 years BP - their morphological variability and the presence of archaic features are indicative to some degree of regional Neanderthal ancestry. The beautifully illustrated monograph addresses - for the first time - the complete assemblage of the finds, including the human cranial, post cranial, teeth and jaw fragments of several individuals (most of them stored at the Natural History Museum Vienna) as well as the faunal remains and the archaeological objects. Leading scientists present their results, obtained with innovative techniques such as DNA analysis, 3D-morphometry and isotope analysis, which are of great importance for further discussions on both human evolution and archaeological issues.
Oxygen-Ozone therapy is a complementary approach less known than homeopathy and acupuncture because it has come of age only three decades ago. This book clarifies that, in the often nebulous field of natural medicine, the biological bases of ozone therapy are totally in line with classical biochemistry, physiological and pharmacological knowledge. Ozone is an oxidizing molecule, a sort of super active oxygen, which, by reacting with blood components generates a number of chemical messengers responsible for activating crucial biological functions such as oxygen delivery, immune activation, release of hormones and induction of antioxidant enzymes, which is an exceptional property for correctin...
Oxygen-ozone therapy is a complementary approach less known than homeopathy and acupuncture because it has come of age only three decades ago. This book clarifies that, in the often nebulous field of natural medicine, the biological bases of ozone therapy are totally in line with classic biochemical, physiological and pharmacological knowledge. Ozone is an oxidising molecule, a sort of superactive oxygen, which, by reacting with blood components, generates a number of chemical messengers responsible for activating crucial biological functions such as oxygen delivery, immune activation, release of hormones and induction of antioxidant enzymes, which is an exceptional property for correcting t...
Intensive Care Medicine compiles the most recent developments in experimental and clinical research and practice in one comprehensive reference book. The chapters are written by well recognized experts in the field of intensive care and emergency medicine. It is addressed to everyone involved in internal medicine, anesthesia, surgery, pediatrics, intensive care and emergency medicine.
This volume addresses neuronal pain mechanisms at the peripheral, spinal and supraspinal level which are thought to significantly contribute to pain and which may be the basis for the development of new treatment principles. Chapters on nociceptive mechanisms in the peripheral nociceptive system address the concept of hyperalgesic priming, the role of voltage-gated sodium channels in different inflammatory and neuropathic pain states, the hyperalgesic effects of NGF in different tissues and in inflammatory and neuropathic pain states, and the contribution of proteinase activated receptors (PAR) to the development of pain in several chronic pain conditions. Chapters on nociceptive mechanisms in the spinal cord address the particular role of NO and of glial cell activation in the generation and maintenance of inflammatory and neuropathic pain and it discusses the potential role of local inhibitory interneurons, of the endogenous endocannabinoid system and the importance of non-neuronal immune mechanisms in opioid signaling in the control of pain. Furthermore, it is presented how spinal mechanisms contribute to the expression of peripheral inflammation.
In prehistoric societies children comprised 40–65% of the population, yet by default, our ancestral landscapes are peopled by adults who hunt, gather, fish, knap tools, and make art. But these adults were also parents, grandparents, aunts, and uncles who had to make space physically, emotionally, intellectually, and cognitively for the infants, children, and adolescents around them. Growing Up in the Ice Age is a timely and evidence-based look at the lived lives of Paleolithic children and the communities of which they were a part. By rendering these ‘invisible’ children visible, readers will gain a new understanding of the Paleolithic period as a whole, and in doing so will learn how children have contributed to the biological and cultural entities we are today.