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Endometrial Cancer: From Biological to Clinical Approaches
In developed countries, cancer of the endometrium (EC) is the most common cancer of the female reproductive organs, affecting mainly postmenopausal women. The highest incidence of EC is in Northern America and Europe, but its incidence is growing around the world. Several factors influence the risk of developing EC, including: impaired hormone levels, obesity, physical activity, family history, and having been diagnosed with breast or ovarian cancer in the past. For EC, a standard screening test does not exist. It is often diagnosed at stage I/II due to frequent vaginal bleeding, while invasive EC (stage III/IV) is mainly diagnosed in its advanced stage. Despite the different clinical improv...
Calcium Signaling
This volume contains a unique selection of chapters covering a wealth of contemporary topics in this ubiquitous and diverse system of cell signaling. It offers much more than the accessibility and authority of a primary text book, exploring topics ranging from the fundamental aspects of calcium signaling to its varied clinical implications. It presents comprehensive discussion of cutting-edge research alongside detailed analysis of critical issues, at the same time as setting out testable hypotheses that point the way to future scientific endeavors. The contributions feature material on theoretical and methodological topics as well as related subjects including mathematical modeling and simulations. They examine calcium signaling in a host of contexts, from mammalian cells to bacteria, fruit fly and zebrafish. With much of interest to newcomers to the field as well as seasoned experts, this new publication is both wide-ranging and authoritative. The chapter “Calcium Signaling: From Basic to Bedside” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Targeting the PD-1/PD-L1 Cancer Immune Evasion Axis: Challenges and Emerging Strategies
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Targeted Immunotherapy for Cancer
Topic Editor, William Williams, is the president and CEO of BriaCell, which is developing a targeted immunotherapy for breast cancer. This includes raising money to support research and clinical programs and applying for grants. All other Topic Editors declare no competing interests with regards to the Research Topic subject.
CNS and Neurological Disorders
Frontiers in Clinical Drug Research - CNS and Neurological Disorders is an eBook series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system (CNS) and other nerve disorders. The scope of the eBook series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of contemporary molecular targets involved in neurological and CNS disorders. Reviews presented in the series are mainly focused on clinical and therapeutic aspects of novel drugs intended for these targets. Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a valuable...
Me, Myself & My Multiple Myeloma
Me, Myself & My Multiple Myeloma is a cancer-patient memoir written by Ray Hartjen, a multiple myeloma patient diagnosed in March 2019. In this intimate and inspiring account, Ray reflects on every step of his relentless battle with cancer, from working toward a final diagnosis, through an initial induction treatment and an autologous stem cell transplant, and on to maintenance and continuing active treatment. Through it all, Ray shares personal insights into his fight, tending to his systemic physical, mental, emotional and spiritual needs. Fighting cancer or any serious health issue, particularly a chronic condition, can be a daunting quest. Me, Myself & My Multiple Myeloma shows the importance of being mission-forward. Mission, of course, is unique to each individual, and based on values, roles, and the accountabilities associated with each that matter most. Written for cancer patients, their caregivers, and their friends and family, Me, Myself & My Multiple Myeloma is a personal story of proactive accountability, stubborn perseverance, evolving perceptions, growing maturity, and, ultimately, hope.
The Strange Order Of Things
'Damasio undertakes nothing less than a reconstruction of the natural history of the universe ... [A] brave and honest book' The New York Times Book Review The Strange Order of Things is a pathbreaking investigation into homeostasis, the condition of that regulates human physiology within the range that makes possible not only survival but also the flourishing of life. Antonio Damasio makes clear that we descend biologically, psychologically and even socially from a long lineage that begins with single living cells; that our minds and cultures are linked by an invisible thread to the ways and means of ancient unicellular existence and other primitive life-forms; and that inherent in our very chemistry is a powerful force, a striving toward life maintenance that governs life in all its guises, including the development of genes that help regulate and transmit life. The Strange Order of Things is a landmark reflection that spans the biological and social sciences, offering a new way of understanding the origins of life, feeling and culture.
Ancient Remedies for Modern Life
The Secrets to Healing, Resilience and Immunity With the Most Powerful Natural Medicine in History From the bestselling author of Keto Diet Long before the first pharmaceutical companies opened their doors in the 1850s, doctors treated people, not symptoms. And although we've become used to popping pills, patients have finally had it with the dangerous side effects, addiction and over-prescribing - and they're desperate for an alternative. Here's the good news: that alternative has been here all along in the form of ancient treatments used for eons in traditional Chinese, Ayurvedic and Greek medicine. Ancient Remedies for Modern Life is the first comprehensive layman's guide that will bring ...
