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Novel Approaches and Strategies for Biologics, Vaccines and Cancer Therapies takes a look at the current strategies, successes and challenges involved with the development of novel formulations of biologics, vaccines and cancer therapy. This thorough reference on the latest trends in the development of diverse modalities will appeal to a broad community of scientists, students and clinicians. Written by leading authors across academia and industry, this book covers important topics such as unique drug delivery devices, non-parenteral delivery trends, novel approaches to the treatment of cancer, immunotherapy and more. It includes real-world cases and examples which highlight formulations wit...
This book provides a detailed account of the most recent developments, challenges and solutions to seamlessly advance and launch a lyophilized biologics or vaccine product, based on diverse modalities, ranging from antibodies (e.g., monoclonal, fused), complex biologics (e.g., antibody drug conjugate, PEGylated proteins), and vaccines (e.g., recombinant-protein based). The authors adeptly guide the reader through all crucial aspects, from biophysical and chemical stability considerations of proteins, analytical methods, advances in controlled ice nucleation and quality-by-design approaches, alternate drying technology, to latest regulatory, packaging and technology transfer considerations to...
In this monograph, Tatyana Naumenko, Doctor of Arts and a professor at Moscow’s Gnessin Russian Academy of Music, looks at modern Russian musicology through the prism of texts representing it. She mentions subjects addressed in musicological studies, names genres of music that scholars preference to explore, and describes modern methods of research and criteria of assessment, largely with the aim of overcoming Soviet-era dogmatism. Special consideration is given to the writing of academic degree dissertations on music in the former Soviet Union and post-Soviet Russia. The Annex lists dissertations approved between 1970 and 2013.
This book presents the opinions of an international panel of specialists that explored the agricultural, commercial, ecological, legal, pharmacological and social future of medicinal and aromatic plants. It represents a wide collection of views, reflecting the diversity of disciplines and interests of the panel members. It highlights the necessity of continued and integrated research on plant sources, conservation, bioactivity, analysis and marketing in examining future scenarios for application and sale of medicinal and aromatic plants. It shows the need for proof of efficacy and safety in drug development and the need to recognize societies contributing plant materials. The development of safe and effective medicinal and aromatic plant products depends upon the collaborative efforts of growers, collectors, conservationists, processors and businesses along with those of educators, sociologists, researchers and investors in developed and developing societies.
Faculties, publications and doctoral theses in departments or divisions of chemistry, chemical engineering, biochemistry and pharmaceutical and/or medicinal chemistry at universities in the United States and Canada.
'If you read only one thriller this year; make it this one' Daily Mail 'Gob-smackingly, heart-stoppingly, breath-holdingly brilliant' Ruth Jones ------------ THREE HOURS TO SAVE THE PEOPLE YOU LOVE In rural Somerset in the middle of a blizzard, the unthinkable happens: a school is under siege. Pupils and teachers barricade themselves into classrooms, the library, the theatre. The headmaster lies wounded in the library, unable to help his trapped students and staff. Outside, a police psychiatrist must identify the gunmen, while parents gather desperate for news. In three intense hours, all must find the courage to stand up to evil and save the people they love. A TOP 10 SUNDAY TIMES BESTSELLE...
This volume is a compendium of research on the Belt Supergroup. It is an outgrowth of Belt Symposium IV, held in Salmon, Idaho, in July, 2003, in conjunction with the Tobacco Root Geological Society annual field conference. Because of the geographic extent and great thickness of the Belt Supergroup, years of work have been required before conclusions are "bona fide". The Mesoproterozoic Belt Supergroup of western Montana and adjacent areas is geologically and economically important, but it has been frustratingly hard to understand. The previous Belt Symposium volumes offer an historical view of the progress of the science of geology in the western United States. The advent of U-Pb geochronology, especially using the ion microprobe (SHRIMP) and laser-ablation ICPMS, has injected geochronometric reality into long-standing arguments about Belt stratigraphy. Several papers in this volume utilize these new tools to provide constraints on age and correlation of Belt strata (Chamberlain et al., Lewis et al., Link et al., and Doherty et al.)
At the time of its first publication, The Human Experience was a historic publishing event, the first of its kind: an anthology published simultaneously in the United States and the Soviet Union that brought together forty brilliant and celebrated contemporary writers--half of them Americans, half of them Russians--in deeply felt stories and poems which provided glimpses of the life, the work, the play, the textures and humors of the two countries, giving us insight into how we differed, what we had in common.