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Protein Misfolding, Aggregation and Conformational Diseases
The second volume continues to fill the gap in protein review and protocol literature. It does this while summarizing recent achievements in the understanding of the relationships between protein misfoldings, aggregation, and development of protein deposition disorders. The focus of Part B is the molecular basis of differential disorders.
The Forgotten Feminists: Women Who Led Scientific Revolutions
The Forgotten Feminists highlights the incredible women who played pivotal roles in scientific revolutions but whose contributions were overshadowed by their male counterparts. From Ada Lovelace’s groundbreaking work in computer science to Marie Curie’s pioneering research on radioactivity, this book uncovers the stories of women whose achievements have been historically overlooked. It celebrates their intelligence, resilience, and determination in fields that were often hostile to women’s involvement. In addition to telling the stories of these extraordinary women, The Forgotten Feminists explores how their work has shaped modern science and technology. The book also examines the systemic challenges these women faced in their careers, from societal discrimination to the lack of opportunities, and how their perseverance in the face of adversity helped pave the way for future generations of women scientists and innovators.
Stem Cell Battles
This is a one-of-a-kind book: combining easy-to-understand science, in-the-trenches political warfare, and inspirational stories. It aims to give hope to individuals and families who suffer from chronic disease or disability; to point out how ordinary people can make an extraordinary difference in the battle to ease suffering and save lives through supporting medical research; to share in "people talk" some of the amazing progress already achieved in the new field of stem cell research; to show how even such a magnificent success as the California stem cell program is under constant attack from ideological groups; to offer medical research as a force for international cooperation; to suggest...
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Working with Stem Cells
The content covered encompass not only the theoretic and methodological aspects for culturing human pluripotent stem cells, but also the establishment of induced pluripotent stem cells and their differentiation into specific cellular subtypes. This book has the most updated methods and technologies in an accessible and clear language, presenting protocols developed and optimized by researchers that use them every day. Stem cell research is a growing field that offers the potential to comprehend mechanisms of neural development and tissue regeneration and maintenance as well as the development-related human diseases and the establishment of novel therapies. Questions of basic biology can also be exploited by this cutting-edge approach.
Neurogenetics
The rapid identification and characterization of genes of neurological relevance holds great potential for offering insight into the diagnosis, management, and und- standing of the pathophysiologic mechanisms of neurological diseases. This volume in the Methods in Molecular BiologyTM series was conceived to highlight many of the contemporary methodological approaches utilized for the characterization of neu- logically relevant gene mutations and their protein products. Although an emphasis has been placed upon descriptions of methodologies with a defined clinical utility, it is hoped that Neurogenetics: Methods and Protocols will appeal not only to clinical laboratory diagnosticians, but als...
Twas At 20: A History Of The Third World Academy Of Sciences
For the past 20 years, the Third World Academy of Sciences (TWAS) has been at the forefront of efforts to promote science and science-based developments in the developing world. This history of TWAS, the first of its kind, seeks to examine the forces that led to the creation of the Academy and that have sustained its growth and development ever since. This is a history of an organization that has made a difference in the advancement of science in the developing world and one that has been operated largely by and for scientists from the South. It provides a unique perspective on the challenges and opportunities that have driven science in the South over the past two decades and offers a window on the progress that has been made and the enormous amount of work that still needs to be done.
Prions and Brain Diseases in Animals and Humans
Most of the world's experts on prions met for a workshop in Erice in August 1996. The aim of the workshop was to discuss the fundamentals of the science ofprions. It was for tunate that so many could be present given the pressure that they were under because of the data presented in March 1996, indicating that Bovine Spongiform Encephalopathy, BSE or Mad Cow Disease, had penetrated the species barrier and was beginning to cause a new dis ease in humans--the new variant ofCreutzfeldt-Jakob Disease, nvCJD. This important and urgent subject became an additional major topic at the workshop. This is a book containing most of the talks plus the abstracts of those unable to find time to write up th...
