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Introduction to Computational Biology
Biology is in the midst of a era yielding many significant discoveries and promising many more. Unique to this era is the exponential growth in the size of information-packed databases. Inspired by a pressing need to analyze that data, Introduction to Computational Biology explores a new area of expertise that emerged from this fertile field- the combination of biological and information sciences. This introduction describes the mathematical structure of biological data, especially from sequences and chromosomes. After a brief survey of molecular biology, it studies restriction maps of DNA, rough landmark maps of the underlying sequences, and clones and clone maps. It examines problems assoc...
Computational Genome Analysis
This book presents the foundations of key problems in computational molecular biology and bioinformatics. It focuses on computational and statistical principles applied to genomes, and introduces the mathematics and statistics that are crucial for understanding these applications. The book features a free download of the R software statistics package and the text provides great crossover material that is interesting and accessible to students in biology, mathematics, statistics and computer science. More than 100 illustrations and diagrams reinforce concepts and present key results from the primary literature. Exercises are given at the end of chapters.
Getting Outside
This is a memoir of a childhood spent on an isolated livestock ranch on the southern coast of Oregon in the mid-twentieth century. The author's family kept heading west until they reached the Pacific Ocean and then stalled for a hundred years. While much of the United States by 1950 was already urbanized, on Four Mile Creek horses were being replaced by tractors, axes by power saws, and coal-oil lamps by electric lights. The contrasts between the myths of the American West and reality are described: living off the land, freedom from all outside authority, cowboys, loggers, wilderness and the conflicted roles of men and women.
Prentice Hall Chemistry
Prentice Hall Chemistrymeets the needs of students with a range of abilites, diversities, and learning styles by providing real-world connections to chemical concepts and processes. The first nine chapters introduce students to the conceptual nature of chemistry before they encounter the more rigorous mathematical models and concepts in later chapters. The technology backbone of the program is the widely praised Interactive Textbook with ChemASAP!, which provides frequent opportunities to practice and reinforce key concepts with tutorials that bring chemistry to students through: Animations, Simulations, Assessment, and Problem-solving tutorials.
A Leader's Call
In our present society, it is increasingly rare to ¬find a leader in any area of life who is known to have noble character and great integrity. The examples of current leadership in all areas leave a lot to be desired. If we are not careful, we are prone to follow in the steps of those wicked leaders mentioned above. King David was known as a man after the heart of God. His was a life worthy of examination and study. He was the greatest king in the history of Israel. Looking at this man's life will challenge all, it will force leaders in all areas to do one thing: to deal with their hearts. To the reader this will be, 'A Leader's Call'.
Combinatorial Pattern Matching
This book constitutes the refereed proceedings of the 11th Annual Symposium on Combinatorial Pattern Matching, CPM 2000, held in Montreal, Canada, in June 2000.The 29 revised full papers presented together with 3 invited contributions and 2 tutorial lectures were carefully reviewed and selected from 44 submissions. The papers are devoted to current theoretical and algorithmic issues of searching and matching strings and more complicated patterns such as trees, regular expression graphs, point sets and arrays as well as to advanced applications of CPM in areas such as Internet, computational biology, multimedia systems, information retrieval, data compression, and pattern recognition.
Collecting Experiments
Databases have revolutionized nearly every aspect of our lives. Information of all sorts is being collected on a massive scale, from Google to Facebook and well beyond. But as the amount of information in databases explodes, we are forced to reassess our ideas about what knowledge is, how it is produced, to whom it belongs, and who can be credited for producing it. Every scientist working today draws on databases to produce scientific knowledge. Databases have become more common than microscopes, voltmeters, and test tubes, and the increasing amount of data has led to major changes in research practices and profound reflections on the proper professional roles of data producers, collectors, ...
Large-scale Genome Sequence Processing
Efficient computer programs have made it possible to elucidate and analyze large-scale genomic sequences. Fundamental tasks, such as the assembly of numerous whole-genome shotgun fragments, the alignment of complementary DNA sequences with a long genome, and the design of gene-specific primers or oligomers, require efficient algorithms and state-of-the-art implementation techniques. This textbook emphasizes basic software implementation techniques for processing large-scale genome sequences and provides executable sample programs. Book jacket.
Bioinformatics: From Nucleic Acids and Proteins to Cell Metabolism
Bioinformatics, in this context the application of computer science to biological problems, has become an indispensable part of any research in the biosciences. Rapid developments in gene sequencing, structure determination as well as rational protein engineering and design have made it necessary for biologists, chemists, and computer scientists to channel their expertise into large scale collaborative projects. This GBF Monograph gives a general overview of the latest versatile activities in bioinformatics: * Biological Data Bases * DNA and RNA * Protein Sequences and Structures * From Molecules to Cell Metabolism The articles have been selected from contributions to a conference on Bioinformatics/Computer Application in the Biosciences, held in October 1995 in Braunschweig at the German National Research Center for Biotechnology.
Sequences
This volume contains all of the papers presented at the "Advanced In ternational Workshop on Sequences: Combinatorics, Compression, Se curity, and Transmission" held Monday June 6 through Saturday June 11, 1988 at the Palazzo Serra di Cassano in Naples and at the Hotel Covo dei Saraceni in Positano, Italy. The event was organized by the Departimento di Informatica ed Ap plicazioni of the University of Salerno in cooperation with the Istituto Italiano per gli Studi Filosofici of Naples and the National Research Council of Italy (C.N.R.). I wish to express my warmest thanks to the members of the Program Committee: Professor B. Bose, Professor S. Even, Professor Z. Galil, Professor A. Lempel, Professor A. Restivo; and to my collaborators: Professor F. De Santis and Professor U. Vaccaro; for their effective, ceaseless help both during the organization of the workshop and dur ing the preparation ofthis volume. Finally, I would like to express my sincere gratitude to all the participants in the Workshop."
