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The art of transforming a circuit idea into a chip has changed permanently. Formerly, the electrical, physical and geometrical tasks were predominant. Later, mainly net lists of gates had to be constructed. Nowadays, hardware description languages (HDL) similar to programming languages are central to digital circuit design. HDL-based design is the main subject of this book. After emphasizing the economic importance of chip design as a key technology, the book deals with VLSI design (Very Large Scale Integration), the design of modern RISC processors, the hardware description language VERILOG, and typical modeling techniques. Numerous examples as well as a VERILOG training simulator are included on a disk.
This textbook is a practical guide to the use of small animal imaging in preclinical research that will assist in the choice of imaging modality and contrast agent and in study design, experimental setup, and data evaluation. All established imaging modalities are discussed in detail, with the assistance of numerous informative illustrations. While the focus of the new edition remains on practical basics, it has been updated to encompass a variety of emerging imaging modalities, methods, and applications. Additional useful hints are also supplied on the installation of a small animal unit, study planning, animal handling, and cost-effective performance of small animal imaging. Cross-calibration methods and data postprocessing are considered in depth. This new edition of Small Animal Imaging will be an invaluable aid for researchers, students, and technicians involved in research into and applications of small animal imaging.
The study is the result of a theological research and is based on current discussions on digitalization in Christian Social Ethics. The book answers questions such as: How can the Church use digitalization to advance her mission in the modern world? Since digitalization has redefined the landscape of evangelization and is now very much favoured by young people, how can the Church use digitalization to engage the young people in her mandate to evangelize the world? This work also examines how digitalization could be used to combat corruption, especially in the Nigerian public and private sectors. It suggests various measures by which internet fraud and corruption could be reduced, using digital tools. It stresses, however, that these measures can only have a positive outcome, if the government and its institutions are sincere and resolute in their determination to curb such corruption.
The diagnostic and therapeutic achievements in radiopharmaceuticals and nuclear medicine instrumentation - PET, SPECT, MR, CT and their hypbrids PET-CT and SPECT-CT - are the result of the interdisciplinary research efforts of cell-biologists, chemists, pharmacologists, physicists, computer-scientists, engineers, nuclear medicine physicians, a
The 5th International Workshop on Medical Imaging and Augmented Reality, MIAR 2010, was held at the China National Convention Center (CNCC), B- jing, China on September 19–20, 2010. MIAR has remained a truly international meeting, bringing together - searchers from all ?elds related to medical image analysis, visualization and targeted intervention.In recent years,technical advances in therapeutic delivery andagrowingdemandforpatient-speci?ctreatmenthaveacceleratedtheclinical applications of MIAR-related techniques. Imaging plays an increasingly imp- tant role in targeted therapy, with interventions such as drug or gene therapy relying on more accurate delivery tailored to individual patients. Rapid progress in surgical methodologies, such as those with robot assistance, demands p- cise guidance from both preoperative and intraoperative imaging. The volume of data available from existing and emerging imaging modalities leads to a - sire for more automated analysis for diagnosis, segmentation and registration. Research in this rapidly developing area is highly multi-disciplinary, integrating research in life sciences, physical sciences, engineering, and medicine.
Written by an interdisciplinary team of medical doctors, computer scientists, physicists, engineers, and mathematicians, Correction Techniques in Emission Tomography presents various correction methods used in emission tomography to generate and enhance images. It discusses the techniques from a computer science, mathematics, and physics viewpoint. The book gives a comprehensive overview of correction techniques at different levels of the data processing workflow. It covers nuclear medicine imaging, hybrid emission tomography (PET-CT, SPECT-CT, PET-MRI, PET-ultrasound), and optical imaging (fluorescence molecular tomography). It illustrates basic principles as well as recent advances, such a...
This book explains in detail the potential value of the hybrid modalities, SPECT-CT and PET-CT, in the imaging of cardiac innervation in a wide range of conditions and diseases, including ischemic heart disease, diabetes mellitus, heart failure, amyloidosis, heart transplantation, and ventricular arrhythmias. Imaging of the brain-heart axis in neurodegenerative disease and stress and of cardiotoxicity is also discussed. The roles of the various available tracers are fully considered, and individual chapters address radiopharmaceutical development under GMP, imaging physics, and kinetic modeling software. Highly relevant background information is included on the autonomic nervous system of the heart and its pathophysiology, and in addition future perspectives are discussed. Awareness of the importance of autonomic innervation of the heart for the optimal management of cardiac patients is growing, and there is an evident need for objective measurement techniques or imaging modalities. In this context, Autonomic Innervation of the Heart will be of wide interest to clinicians, researchers, and industry.
This volume discusses recent research advances in cancer biology, focusing on the role of the tumor microenvironment. Taken alongside its companion volumes, Tumor Microenvironment: Recent Advances covers the latest research on various aspects of the tumor microenvironment, as well as future directions. Useful for introducing the newer generation of researchers to the history of how scientists studied the tumor microenvironment as well as how this knowledge is currently applied for cancer treatments, it will be essential reading for advanced cell biology and cancer biology students, as well as researchers seeking an update on research on the tumor microenvironment.
The here presented book covers different areas of clinical and scientific interest, reaching from donor evaluation to newest methods in immunological diagnostics. But also aspects of daily care of transplant recipients can be found in the carefully selected chapters. Everything driven by the aim to improve the care for all of our transplanted patients.