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With the recent increase in the scope of drug and alcohol problems has come an awareness of the need for solutions. In this context, federal support for research on drug problems increased tremendously during the last 10 to 15 years with the establishment of the National Institute on Drug Abuse (NIDA) and the National Institute on Alcohol Abuse and Alcoholism (NIAAA). Funding from these and other sources has led to a substantial increase in the quantity and quality ofpublished work related to substance abuse. As data accumulate, it is becoming more apparent that substance abuse problems are extremely complex and are influenced by a variety ofbiological psychological, and environmental variab...
The purpose of this book is to review our state of knowledge about the neurobehavioral and psychosocial processes involved in behavioral inhibitory processes and to provide an insight into how these basic research findings may be translated into the practice of drug abuse prevention interventions. Over the last decade, there has been a wealth of information indicating that substance use disorders do not simply reflect an exaggeration of reward seeking behavior, but that they also represent a dysfunction of behavioral inhibitory processes that are critical in exercising self-control. A number of studies have determined that individuals with substance use disorders have poor inhibitory control...
This wide-ranging handbook brings together experts in the sociology of drug abuse prevention. Providing a comprehensive overview of the accumulated knowledge on prevention theory, intervention design, and development and prevention research methodology, this work also promotes prevention science as an evolving field in the practice and policy of drug abuse prevention.
Integrating scientific knowledge with today's most effective treatment options, Addiction Medicine: Science and Practice, 2nd Edition, provides a wealth of information on addictions to substances and behavioral addictions. It discusses the concrete research on how the brain and body are affected by addictions, improving your understanding of how patients develop addictions and how best to personalize treatment and improve outcomes. This essential text is ideal for anyone who deals with patients with addictions in clinical practice, including psychiatrists, health psychologists, pharmacologists, social workers, drug counselors, trainees, and general physicians/family practitioners. - Clearly ...
More and more scientists are applying the concepts of motivation and related constructs to modify the behavior of drug-addicted and dependent people. Here, authors discuss effective ‘translational’ strategies for decreasing and preventing tobacco use.
Nonclinical Assessment of Abuse Potential for New Pharmaceuticals offers a complete reference on the current international regulatory guidelines and details best practice methodology for the three standard animal models used to evaluate abuse potential: physical dependence, self-administration and drug discrimination. This book also includes chapters on alternative models and examples of when you should use these alternatives. Case histories are provided at the end of the book to show how the data generated from the animal models play a pivitol role in the submission package for a new drug. By incorporating all of this information into one book, Nonclinical Assessment of Abuse Potential for New Pharmaceuticals is your single resource for everything you need to know to understand and implement the assessment of abuse liability. Provides a consolidated overview of the complex regulatory landscape Offers best practice methodology for conducting animal studies, including selection of doses and positive control agents that will help you improve your own abuse potential studies Includes real-life examples to illustrate how nonclinical data fit into the submission strategy
Zuckerman received his Ph.D. in psychology from New York University, Graduate School of Arts and Science in 1954 with a specialization in clinical psychology. After graduation, he worked for three years as a clinical psychologist in state hospitals in Norwich, Connecticut and Indianapolis, Indiana. While in the latter position the Institute for Psychiatric Research was opened in the same medical center where he was working as a clinical psychologist. He obtained a position there with a joint appointment in the department of psychiatry. This was his first interdisciplinary experience with other researchers in psychiatry, biochemistry, psychopharmacology, and psychology. His first research are...
The spectrum of addiction disorders presents practitioners with numerous challenges—among them the widening gap between a growing evidence base and the translation of this knowledge into treatment outcomes. Addiction Medicine addresses this disconnect, clearly explaining the role of brain function in drug taking and other habit-forming behaviors, and applying this biobehavioral framework to the delivery of evidence-based treatment. Its state-of-the-art coverage provides clinically relevant details on not only traditional sources of addiction such as cocaine, opiates, and alcohol, but also more recently recognized substances of abuse (e.g., steroids, inhalants) as well as behavioral addicti...
Addiction focuses on the emergence, nature, and persistence of addictive behavior, as well as the efforts of addicts to overcome their condition. Do addicts act of their own free will, or are they driven by forces beyond their control? Do structured treatment programs offer more hope for recovery? What causes relapses to occur? Recent scholarship has focused attention on the voluntary aspects of addiction, particularly the role played by choice. Addiction draws upon this new research and the investigations of economists, psychiatrists, philosophers, neuropharmacologists, historians, and sociologists to offer an important new approach to our understanding of addictive behavior. The notion tha...
The papers in these proceedings of the September 2003 conference examine this key period in life and its associated behavioral and emotional problems. General paper topics include risk taking and novelty seeking, brain and cognitive development, the interrelationships between hormones and behavior, nicotine and alcohol use, sleep and arousal, and the regulation of behavior and emotion. The volume includes short papers on human and animal studies. Papers include their own references. Annotation ©2004 Book News, Inc., Portland, OR (booknews.com).