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This comprehensive encyclopedia supplies the reader with concise information on the molecular pathophysiology of disease. Entries include defined diseases (such as Parkinson's disease) as well as pathophysiological entities (such as tremor). The 1,200 essays are brilliantly structured to allow rapid retrieval of the desired information. For more detailed reading, each entry is followed by up to five references. Individual entries are written by leading experts in the respective area of research to ensure state-of-the-art descriptions of the mechanisms involved. It is an invaluable companion for clinicians and scientists in all medical disciplines.
This volume highlights major contributions that identify new developments and directions in the field over the past decade, as well as challenges for the foreseeable future. An integration of information from laboratory and epidemiological studies, male reproduction and teratology can be found throughout the volume. The range of topics include parental legacies and genomics, lifestyle, occupational and therapeutic paternal exposures and effects; effects on the gamete-packaging of human sperm; role of DNA repair and germ cell apoptosis; stem cells, epigenetics and closing; model systems and implications to clinicians and general counselors.
Infertility affects approximately 15% of couples of reproductive age. High live birth rates rely on many advanced technologies in infertility treatment, including more accurate clinical diagnosis and patient management as well as state-of-the-art in vitro fertilization (IVF) technologies. This book discusses infertility and infertility treatments such as embryo implantation, non-invasive preimplantation genetic diagnosis (PGT), oocyte cryopreservation, cryopreservation of small numbers of sperm, and embryo culture technologies. It delivers new information and data valuable to clinicians, embryologists, and others in infertility treatment.
Vitamins and Hormones serial highlights new advances in the field with this new volume presenting interesting chapters. Each chapter is written by an international board of authors. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in Vitamins and Hormones series Updated release includes the latest information on the Adrenal Gland
Cheryl S. Watson University o/Texas Medical Branch Cellular steroid action has been thoroughly studied in the nuclear compartment. However, nuclear steroid receptor mechanisms have been unable to explain some of the rapid activities of steroids, partiCUlarly those which occur in a time frame of seconds to minutes [reviewed in (1;2)]. Based on these and other considerations, an alternative membrane-associated receptor form was long ago proposed to exist (3). Others interpret the location of the steroid receptors mediating these rapid effects as peri membrane or cytoplasmic. New experimental tools have been brought to bear on the topic of receptors for steroids which mediate non-genomic actions, and thus investigative activity and focus regarding this type of steroid receptor has recently increased significantly. However, there may be multiple answers to the question "how do steroids mediate rapid nongenomic effects?" Steroid actions initiated at the cell membrane can impinge on important phases in the lifespan of a cell: proliferation, migration, differentiation, and release of hormones or neurotransmitters functioning as signals to other cells.
Antioxidants, Volume 121 in the Vitamins and Hormones series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Vitamins and Hormones series Updated release includes the latest information on Antioxidants