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Biomarkers: Precision Nutrition in Chronic Diseases
Chronic diseases such as obesity, diabetes, and cardiovascular disease are major causes of morbidity and mortality worldwide with increasing prevalence in all age groups, genders, and ethnicities. Emerging evidence suggests that precision nutrition plays a pivotal role in the prevention and management of chronic diseases and has been recognized as a key focus for the next ten years of health research. Currently, one of the major challenges in precision nutrition is the valid and reliable assessment of foods and nutrients intake, especially whole foods (e.g., fermented foods) and macromolecules (e.g., polysaccharides), as well as their impact on host health and disease. Strong evidence has su...
Annual Report
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Current Status of Natural Products Targeting Alzheimer’s Disease
Despite more than fifty years of intensive research on Alzheimer’s disease (AD) drug discovery, up till now only four medicines are approved by FDA for its treatment; among which three are acetylcholinesterase (AChE) inhibitors (donepezil, galantamine, and rivastigmine) and one is N-Methyl-D-aspartate (NMDA) antagonist memantine. These medications were launched during the initial research for AD but were not able to provide satisfactory results because of their limited efficacy and numerous side effects. The high-profile failure of late-stage clinical trials by prominent pharma firms for biomolecules that showed promising results in experimental models has added to the dissatisfaction of d...
Handbook of Microbiome and Gut-Brain-Axis in Alzheimer’s Disease
Despite being confined to the gastrointestinal tract, the gut microbiome has a wide impact on human physiology, supplementing its host’s biochemistry in a complex symbiotic relationship. Research in the field has evolved rapidly in the last decade, and we are now developing a better understanding of how our gut microbiome can influence our immune systems, metabolism, neurological signaling, and perhaps most unexpectedly, our brains; a phenomenon described as the gut-brain-axis. This book, ‘Handbook of Microbiome and Gut-Brain-Axis in Alzheimer’s Disease’, sets out to explore the complex role of the microbiome with regard to Alzheimer’s disease (AD). The microbiome is a critical and...
Type Noun Constructions in Slavic, Germanic and Romance Languages
This volume is the first dedicated to the comprehensive, in-depth analysis of constructions with nouns like ‘type’ and ‘sort’. It focuses on type noun constructions in Romance, Germanic and Slavic languages, integrating the different descriptive traditions that had been developed for each language family. As a result, a greater variety of type noun constructions is revealed than in the hitherto more fragmented literature. But attention is also drawn to the cross-linguistic similarity of the new pragmatic meanings, such as ad hoc and approximative categorization, hedging, focus and filler uses, and the new grammatical functions in NPs (e.g. phoric uses), clauses (e.g. adverbial uses) ...
Mexican Political Biographies, 1884–1934
Here is an authoritative reference work that makes biographies of prominent Mexican national politicians from the period 1884–1934 available in English. Like the author's biographical directory for the years 1935–2009, it draws on many years of research in Mexico and the United States and seeks not only to provide accurate biographical information about each entry but also, where possible and appropriate, to connect these politicians to more recent leadership generations. Thus, Mexican Political Biographies, 1884-1934 not only is a useful historical source but also provides additional information on the family backgrounds of many contemporary figures. The work includes those figures who ...
Thanks to Life
Chilean musician and artist Violeta Parra (1917–1967) is an inspiration to generations of artists and activists across the globe. Her music is synonymous with resistance, and it animated both the Chilean folk revival and the protest music movement Nueva Canción (New Song). Her renowned song “Gracias a la vida” has been covered countless times, including by Joan Baez, Mercedes Sosa, and Kacey Musgraves. A self-taught visual artist, Parra was the first Latin American to have a solo exhibition at the Museum of Decorative Arts in the Louvre. In this remarkable biography, Ericka Verba traces Parra’s radical life and multifaceted artistic trajectory across Latin America and Europe and on ...
Golf in the Tropics
This guide to the world-renowned golf courses of Colombia showcases courses by the seashore, in the mountains, and on the plains in a country where golf can be played every day of the year.
