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Esta obra, organizada pelo Grupo de pesquisa Multimundos – Estudos das Tensões Contemporâneas, é o 4° Volume da coleção Cadernos Multimundos. Reúne textos de pesquisadores do Brasil, México, Portugal e Espanha, conferencistas no Seminário Internacional Comunicar Ciência: Democracia, Cultura e Audiovisual, em 2022. As discussões envolvem negacionismo, ataques à ciência e à democracia e a emergência da produção de conhecimento a partir da comunicação multimodal, como a experiência do Ensaio Audiovisual Científico.
Lucas' "The Art of Public Speaking" is the leading public speaking textbook in the field. Whether a novice or an experienced speaker when beginning the course, every student will learn how to be a better public speaker through Lucas' clear explanations. Creative activities, vivid examples, annotated speech samples, and foundation of classic and contemporary rhetoric provide students a strong understanding of public speaking. When instructors teach from this textbook, they benefit from Lucas' Integrated Teaching Package. The Annotated Instructor's Edition and Instructor's Manual, both written by Steve Lucas, provide teaching tips and give outlines on how to use the various supplements. As a result, instructors are able to see various teaching examples, how to integrate technology, and analyses and discussion questions for video clips in class. The Annotated Instructor's Edition, Instructor's Manual, Test Bank, CDs, videos, and other supplements provide instructors the tools needed to create a dynamic classroom. This edition has a supplement to meet the needs of online classes, Teaching Public Speaking Online with The Art of Public Speaking.
Fragment-based drug discovery is a rapidly evolving area of research, which has recently seen new applications in areas such as epigenetics, GPCRs and the identification of novel allosteric binding pockets. The first fragment-derived drug was recently approved for the treatment of melanoma. It is hoped that this approval is just the beginning of the many drugs yet to be discovered using this fascinating technique. This book is written from a Chemist's perspective and comprehensively assesses the impact of fragment-based drug discovery on a wide variety of areas of medicinal chemistry. It will prove to be an invaluable resource for medicinal chemists working in academia and industry, as well as anyone interested in novel drug discovery techniques.
This book comprehensively covers the mechanisms of action and inhibitor design for HIV-1 integrase. It serves as a resource for scientists facing challenging drug design issues and researchers in antiviral drug discovery. Despite numerous review articles and isolated book chapters dealing with HIV-1 integrase, there has not been a single source for those working to devise anti-AIDS drugs against this promising target. But this book fills that gap and offers a valuable introduction to the field for the interdisciplinary scientists who will need to work together to design drugs that target HIV-1 integrase.
A study of the civilization of the Zuni Indians, the native of Dubu, and the Kawakiutl Indians.
This book is a printed edition of the Special Issue "Translocator Protein (TSPO)" that was published in IJMS
This book does not aim to document comprehensively the extraordinarily rich activity in New York City in the early 1960's. Instead, the author focuses on one year, 1963. This was the most productive year of the period 1958-64, the transition between the Fifties and Sixties. The author also focuses on one other place---Greenwich Village in lower Manhattan. For it was primarily here, in a place already historically and culturally mythologized as avant-garde terrain, that the emerging generation of vanguard artists lived, worked, socialized, and remade the history of the avant-garde. - from the Introduction.
This first book specifically dedicated to ectoparasite drug discovery is unique in providing insights from the veterinary as well as the medical perspective, covering research from both industry and academia while paving the way for new synergies between the two research communities. Edited by a team combining 80 years of experience in academic research and industrial antiparasitic drug discovery, this volume of Drug Discovery in Infectious Diseases summarizes current knowledge in this rapidly expanding field. Comprehensive yet concise, this ready reference blends solid background information on ectoparasite biology with the very latest methods in ectoparasite drug discovery. Three major parts cover current ectoparasite control strategies and the threat of drug resistance, screening and drug evaluation, and the new isoxazoline class of ectoparasiticides. The future potential of mechanism-based approaches for repellents and parasiticides is thoroughly discussed, as are strategies for vaccines against ectoparasites, making the book ideal for parasitologists in academia as well as researchers working in the pharmaceutical industry.