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The Influence Of The Infusion Of Ephedrine And Phenylephrine On The Stability Of The Circulation After Subarachnoid Anesthesia In Senior Adults
ABSTRACTBackgroundWe studied the influence of ephedrine or phenylephrine infusion administered immediately after spinal anesthesia (SA) on hemodynamics in elderly orthopedic patients.MethodsA prospective, randomized, double-blind, placebo-controlled study. After a subarachnoid injection of 15 mg of levobupivacaine, the participants received an infusion of either ephedrine 20 mg (E group), phenylephrine 250 mcg (P group) or saline (C group) within 30 minutes. We measured blood pressure, cardiac index (CI) and heart rate (HR) 15 minutes before and 30 minutes after SA.Results70 patients were included in the final analysis. At the end of measurements, mean arterial pressure (MAP) decreased signi...
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