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Identification of Binding Partners of a Novel P Falciparum Exported Protein
Plasmodium falciparum is the causative agent of the most severe form of malaria. This parasite drastically modifies its host cell, the erythrocyte, to create a hospitable environment for its growth and reproduction. In order for these modifications to occur, the parasite secretes proteins into the erythrocyte. While the secretion machinery is still unknown, many secreted proteins have been found to have a hydrophobic signal sequence and a novel host-targeting signal downstream of the hydrophobic sequence. A novel P. falciparum protein has been shown to be secreted from the parasitophorous vacuole, yet it lacks both a hydrophobic signal sequence and a host-targeting signal. It was hypothesized that this protein, Pfl2110c, must interact with other proteins as it migrates into the erythrocyte. Using immunofluorescence assays and co-immunoprecipitation experiments, I found that Pfl2110c interacts with several parasite proteins as well as with the erythrocyte cytoskeleton. Therefore, Pfl2110c was renamed skeleton-binding protein 2 (SBP-2).System requirements: World Wide Web browser, and PDF reader.
Empty Houses
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Self Portrait in Green
'NDiaye is a hypnotic storyteller with an unflinching understanding of the rock-bottom reality of most people's life.' New York Times ' One of France's most exciting prose stylists.' The Guardian. Obsessed by her encounters with the mysterious green women, and haunted by the Garonne River, a nameless narrator seeks them out in La Roele, Paris, Marseille, and Ouagadougou. Each encounter reveals different aspects of the women; real or imagined, dead or alive, seductive or suicidal, driving the narrator deeper into her obsession, in this unsettling exploration of identity, memory and paranoia. Self Portrait in Green is the multi-prize winning, Marie NDiaye's brilliant subversion of the memoir. Written in diary entries, with lyrical prose and dreamlike imagery, we start with and return to the river, which mirrors the narrative by posing more questions than it answers.
Doing Business 2014
Eleventh in a series of annual reports comparing business regulations in 189 economies, Doing Business 2014 measures regulations affecting 11 areas of everyday business activity around the world.
Applied Computer Sciences in Engineering
This volume constitutes the refereed proceedings of the 8th Workshop on Engineering Applications, WEA 2021, held in Medellín, Colombia, in October 2021. Due to the COVID-19 pandemic the conference was held in a hybrid mode. The 33 revised full papers and 11 short papers presented in this volume were carefully reviewed and selected from 127 submissions. The papers are organized in the following topical sections: computational intelligence; bioengineering; Internet of Things (IoT); optimization and operations research; engineering applications.
The IV Latin American Metabolic Profiling Society (LAMPS) symposium 2022
This Research Topic aims to gather the proceedings of the “IV Latin American Metabolic Profiling Society (LAMPS) Symposium”. Since the first Symposium in 2014 in Lima, Perú, the Latin American Metabolic Profiling Society (LAMPS) has periodically gathered researchers from the region to share their work. Though the discipline is still underdeveloped in Latin America, past meetings held in Rosario, Argentina, in 2016, and in Rio de Janeiro, Brazil, in 2018, have showcased presentations in all areas of metabolomics. After a hiatus of two years imposed by the COVID-19 pandemic, the fourth edition of the LAMPS Symposium will be held in Cartagena de Indias, Colombia, this coming November (2nd ...
Illustrators Annual 2020
Illustrators Annual 2020 is the 2020 edition of Chronicle Books' yearly publication celebrating artists featured at the Bologna Children's Book Fair. Selected by the year's jury at the fair, these illustrators represent the most daring, exciting artistic minds working across the world. Celebrating debut and storied talent from around the world--talent poised to engage a whole new generation of book lovers--this glorious compendium can be read cover-to-cover or browsed through at random. * An annual publication that brings groundbreaking art from around the world to the English-speaking market * Inspires readers to marvel at the brilliance of the gifts shared by children's book illustrators *...
Latin American Economic Outlook 2021 Working Together for a Better Recovery
The Latin American Economic Outlook 2021: Working Together for a Better Recovery aims to analyse and provide policy recommendations for a strong, inclusive and environmentally sustainable recovery in the region. The report explores policy actions to improve social protection mechanisms and increase social inclusion, foster regional integration and strengthen industrial strategies, and rethink the social contract to restore trust and empower citizens at all stages of the policy‐making process.
Killing the Water
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